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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 44.5
Min nTPM: 18.9
Std nTPM: 5.0
Median nTPM:
414_1
84 years, female
44.5
217_1
76 years, male
42.8
413_1
59 years, female
40.3
163_1
78 years, male
38.6
447_1
81 years, male
37.8
389_1
86 years, female
37.6
307_1
66 years, female
37.0
308_1
70 years, female
37.0
375_1
74 years, female
36.7
503_1
68 years, male
36.7
315_1
62 years, female
36.0
499_1
55 years, female
36.0
518_1
75 years, female
36.0
172_1
72 years, female
35.6
246_1
77 years, male
35.6
292_1
71 years, male
35.1
264_1
73 years, female
34.9
321_1
62 years, female
34.6
425_1
59 years, female
34.5
117_1
61 years, male
33.9
32_1
67 years, male
33.6
379_1
60 years, male
33.6
316_1
62 years, male
32.9
347_1
72 years, male
32.7
517_1
88 years, male
32.7
319_1
81 years, male
32.4
466_1
57 years, female
32.2
142_1
61 years, female
32.1
317_1
60 years, male
32.1
490_1
67 years, female
32.1
415_1
77 years, female
32.0
41_1
94 years, female
31.8
288_1
66 years, female
31.8
189_1
76 years, male
31.7
318_1
68 years, male
31.5
396_1
62 years, male
31.2
115_1
83 years, male
31.1
386_1
76 years, male
31.0
18_1
88 years, male
30.9
405_1
91 years, male
30.9
237_1
82 years, male
30.5
295_1
61 years, female
30.3
322_1
76 years, male
30.2
468_1
89 years, male
30.1
173_1
67 years, male
30.0
177_1
74 years, male
30.0
265_1
87 years, male
30.0
394_1
75 years, female
30.0
324_1
76 years, male
29.9
384_1
83 years, male
29.8
229_1
69 years, female
29.4
153_1
70 years, female
29.3
162_1
79 years, female
29.3
218_1
71 years, female
29.2
254_1
77 years, female
29.0
351_1
91 years, male
29.0
81_1
67 years, male
28.8
291_1
76 years, male
28.8
35_1
74 years, female
28.5
354_1
81 years, female
28.5
251_1
78 years, male
28.3
353_1
82 years, female
28.2
355_1
70 years, female
28.2
89_1
63 years, male
28.1
139_1
64 years, female
28.1
350_1
84 years, female
28.1
404_1
82 years, female
27.9
149_1
88 years, male
27.8
406_1
79 years, male
27.7
243_1
75 years, male
27.2
335_1
73 years, female
27.2
286_1
68 years, female
27.1
314_1
67 years, male
27.1
348_1
84 years, male
26.6
376_1
75 years, female
26.6
349_1
83 years, male
26.4
526_1
61 years, male
26.3
126_1
63 years, male
26.2
137_1
83 years, male
26.2
145_1
84 years, male
26.1
266_1
85 years, male
25.7
352_1
62 years, male
25.7
320_1
89 years, female
25.6
495_1
57 years, female
24.9
9_1
66 years, female
24.8
293_1
68 years, female
24.3
4_1
88 years, female
24.2
313_1
79 years, female
24.2
501_1
88 years, male
24.2
452_1
88 years, female
24.1
43_1
64 years, female
23.8
120_1
70 years, female
23.6
356_1
87 years, female
23.6
6_1
73 years, female
23.0
109_1
81 years, female
23.0
311_1
78 years, male
22.9
2_1
77 years, female
22.5
491_1
89 years, female
22.4
119_1
70 years, female
21.7
480_1
63 years, male
21.5
377_1
82 years, female
21.2
506_1
65 years, male
19.8
17_1
71 years, male
19.2
99_1
64 years, male
19.2
42_1
85 years, male
18.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
