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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 245.4
Min nTPM: 67.2
Std nTPM: 32.9
Median nTPM:
415_1
77 years, female
245.4
246_1
77 years, male
214.1
414_1
84 years, female
197.2
466_1
57 years, female
184.8
490_1
67 years, female
182.0
142_1
61 years, female
181.9
379_1
60 years, male
174.3
162_1
79 years, female
171.1
153_1
70 years, female
169.3
266_1
85 years, male
164.8
413_1
59 years, female
162.5
375_1
74 years, female
159.4
81_1
67 years, male
155.3
137_1
83 years, male
154.0
43_1
64 years, female
152.3
89_1
63 years, male
151.2
119_1
70 years, female
148.4
526_1
61 years, male
148.3
503_1
68 years, male
147.5
491_1
89 years, female
146.2
149_1
88 years, male
145.8
32_1
67 years, male
145.7
42_1
85 years, male
143.3
308_1
70 years, female
142.4
468_1
89 years, male
139.2
254_1
77 years, female
137.4
217_1
76 years, male
137.2
229_1
69 years, female
136.1
265_1
87 years, male
135.7
315_1
62 years, female
133.4
126_1
63 years, male
132.5
394_1
75 years, female
131.4
307_1
66 years, female
128.7
35_1
74 years, female
126.7
313_1
79 years, female
126.6
499_1
55 years, female
126.1
389_1
86 years, female
125.2
314_1
67 years, male
124.8
17_1
71 years, male
124.1
6_1
73 years, female
123.0
352_1
62 years, male
121.8
355_1
70 years, female
121.5
120_1
70 years, female
120.2
425_1
59 years, female
119.7
117_1
61 years, male
119.3
18_1
88 years, male
119.1
311_1
78 years, male
119.1
404_1
82 years, female
115.3
115_1
83 years, male
113.6
324_1
76 years, male
111.8
288_1
66 years, female
109.8
139_1
64 years, female
108.0
237_1
82 years, male
107.7
243_1
75 years, male
107.5
335_1
73 years, female
107.5
377_1
82 years, female
107.3
189_1
76 years, male
106.6
9_1
66 years, female
106.0
354_1
81 years, female
105.8
286_1
68 years, female
104.8
2_1
77 years, female
104.4
396_1
62 years, male
104.0
447_1
81 years, male
103.7
264_1
73 years, female
103.3
347_1
72 years, male
102.8
386_1
76 years, male
102.8
350_1
84 years, female
102.5
251_1
78 years, male
101.6
145_1
84 years, male
101.2
172_1
72 years, female
100.8
109_1
81 years, female
100.3
517_1
88 years, male
97.3
99_1
64 years, male
97.2
501_1
88 years, male
95.6
173_1
67 years, male
95.3
495_1
57 years, female
94.9
348_1
84 years, male
94.2
317_1
60 years, male
93.9
292_1
71 years, male
93.1
4_1
88 years, female
91.8
321_1
62 years, female
91.6
518_1
75 years, female
91.6
452_1
88 years, female
91.5
405_1
91 years, male
90.1
291_1
76 years, male
89.7
349_1
83 years, male
89.4
376_1
75 years, female
88.7
295_1
61 years, female
88.0
356_1
87 years, female
87.6
318_1
68 years, male
85.2
177_1
74 years, male
84.8
293_1
68 years, female
84.0
319_1
81 years, male
83.3
322_1
76 years, male
81.8
384_1
83 years, male
81.7
41_1
94 years, female
81.1
163_1
78 years, male
80.8
480_1
63 years, male
80.6
406_1
79 years, male
80.3
351_1
91 years, male
78.9
218_1
71 years, female
78.0
316_1
62 years, male
72.8
506_1
65 years, male
72.8
353_1
82 years, female
71.2
320_1
89 years, female
67.2
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
