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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:130.9 nTPM
HPA:130.9 nTPM
GTEx:112.1 nTPM
FANTOM5:60.7 Scaled Tags Per Million
Pig:31.9 nTPM
Mouse:190.0 nTPM
Allen mouse:9.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 130.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 125.3
2019 Male, age 18, unknown 138.1
2586 Male, age 75, left hemisphere 133.4
1833 Male, age 53, unknown 125.9
1827 Male, age 72, unknown 125.0
2828 Female, age 72, unknown 123.1
1870 Female, age 42, unknown 122.9
1830 Male, age 51, unknown 122.8
2411 Female, age 72, unknown 122.8
2219 Male, age 76, both hemispheres 120.5
2666 Male, age 74, left hemisphere 118.4
Dorsal raphe nucleus
nTPM: 124.2
1828 Male, age 53, unknown 127.3
2298 Female, age 72, unknown 125.8
2047 Male, age 72, unknown 124.3
2750 Male, age 76, both hemispheres 122.9
2016 Female, age 72, unknown 120.4
Inferior colliculus
nTPM: 130.9
1848 Female, age 42, unknown 131.8
1890 Male, age 53, unknown 131.2
2097 Female, age 72, unknown 130.6
2849 Male, age 72, unknown 129.9
Median raphe nucleus
nTPM: 122.3
2220 Male, age 76, midline 122.3
Pedunculopontine tegmental nucleus
nTPM: 122.3
1921 Female, age 85, both hemispheres 123.2
2338 Male, age 61, both hemispheres 122.0
2334 Male, age 80, both hemispheres 121.7
Periaquaductal grey, anterior
nTPM: 118.6
2502 Female, age 75, unknown 122.8
1795 Male, age 51, unknown 116.9
1947 Male, age 18, unknown 116.0
Periaquaductal grey, dorsal
nTPM: 119.2
2464 Female, age 72, unknown 121.4
2850 Male, age 76, both hemispheres 119.8
1840 Male, age 53, unknown 119.1
1831 Male, age 72, unknown 116.7
Periaquaductal grey, lateral
nTPM: 117.0
2272 Male, age 74, both hemispheres 117.6
2140 Male, age 76, both hemispheres 117.1
2053 Male, age 18, unknown 116.4
Pretectal area
nTPM: 126.7
2007 Male, age 72, unknown 138.0
1817 Female, age 42, unknown 136.5
1944 Female, age 72, unknown 134.0
2667 Female, age 75, unknown 130.5
2407 Male, age 75, both hemispheres 130.2
1816 Male, age 51, unknown 129.6
1815 Male, age 53, unknown 126.2
2316 Male, age 76, right hemisphere 117.6
2825 Male, age 18, unknown 117.6
2273 Male, age 74, both hemispheres 117.5
2224 Female, age 72, unknown 116.2
Red nucleus
nTPM: 124.8
2785 Male, age 18, unknown 134.4
1821 Female, age 72, unknown 130.2
2769 Male, age 72, unknown 126.5
2227 Male, age 72, unknown 125.3
2584 Male, age 75, left hemisphere 124.7
2588 Male, age 74, left hemisphere 123.4
1954 Female, age 42, unknown 123.1
2823 Male, age 76, right hemisphere 122.8
1865 Male, age 51, unknown 122.6
1904 Male, age 53, unknown 122.3
2725 Female, age 75, unknown 121.5
2503 Female, age 72, unknown 120.7
Substantia nigra
nTPM: 126.6
1889 Female, age 72, unknown 132.9
1941 Male, age 53, unknown 132.6
1916 Female, age 42, unknown 131.7
1851 Male, age 51, unknown 128.6
2665 Male, age 74, both hemispheres 128.5
2583 Male, age 75, right hemisphere 127.6
2699 Male, age 18, unknown 125.4
2241 Male, age 72, unknown 121.1
2409 Female, age 72, unknown 118.7
2590 Female, age 75, unknown 118.5
Superior colliculus
nTPM: 124.4
2087 Female, age 72, unknown 130.5
1895 Male, age 76, right hemisphere 129.0
2664 Male, age 75, both hemispheres 128.5
2668 Female, age 75, unknown 126.4
1839 Male, age 51, unknown 125.4
1796 Male, age 53, unknown 123.7
2587 Male, age 74, left hemisphere 120.9
1995 Male, age 72, unknown 120.5
1913 Female, age 42, unknown 120.4
2261 Male, age 18, unknown 118.8
Ventral tegmental area
nTPM: 121.3
1915 Female, age 42, unknown 127.4
2410 Female, age 72, unknown 126.4
2218 Male, age 76, both hemispheres 122.1
1942 Male, age 51, unknown 120.2
2223 Female, age 72, unknown 116.7
2021 Male, age 53, unknown 115.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 112.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 112.1
Samples: 139

Max nTPM: 268.2
Min nTPM: 56.2
Std nTPM: 28.5
Median nTPM: 105.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 268.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 202.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 195.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 173.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 170.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 169.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 168.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 167.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 164.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 155.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 153.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 152.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 151.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 148.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 148.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 148.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 146.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 144.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 142.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 141.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 138.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 138.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 136.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 135.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 134.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 134.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 129.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 128.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 127.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 125.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 121.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 121.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 121.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 120.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 120.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 120.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 119.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 119.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 119.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 119.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 118.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 118.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 117.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 116.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 115.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 115.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 114.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 114.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 114.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 113.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 112.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 112.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 112.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 112.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 111.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 110.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 110.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 109.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 109.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 109.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 109.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 109.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 108.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 108.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 107.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 106.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 106.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 106.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 106.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 105.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 105.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 105.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 105.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 104.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 104.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 104.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 104.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 103.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 103.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 103.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 102.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 102.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 102.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 101.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 101.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 101.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 100.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 100.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 100.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 99.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 99.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 99.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 99.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 99.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 98.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 98.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 98.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 97.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 97.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 97.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 97.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 96.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 96.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 95.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 94.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 94.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 93.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 92.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 92.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 92.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 92.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 91.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 91.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 90.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 90.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 90.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 89.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 88.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 88.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 87.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 87.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 87.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 86.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 85.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 83.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 82.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 81.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 80.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 78.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 78.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 77.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 76.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 76.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 74.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 70.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 60.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 56.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 60.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 60.7
FF:10158-103A5 76 years, female 60.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 31.9
Pig sample Sample description nTPM
Midbrain
nTPM: 24.5
Samples: 4

Max nTPM: 29.5
Min nTPM: 19.3
Sample A Female 20.2
Sample B Female 19.3
Sample C Male 29.5
Sample D Male 28.9
Periaqueductal gray
nTPM: 20.3
Samples: 3

Max nTPM: 21.8
Min nTPM: 19.0
Sample B Female 20.2
Sample C Male 21.8
Sample D Male 19.0
Substantia nigra
nTPM: 19.3
Samples: 4

Max nTPM: 23.0
Min nTPM: 15.6
Sample A Female 23.0
Sample B Female 15.6
Sample C Male 21.0
Sample D Male 17.6
Superior colliculi
nTPM: 31.9
Samples: 4

Max nTPM: 41.5
Min nTPM: 17.6
Sample A Female 34.5
Sample B Female 17.6
Sample C Male 41.5
Sample D Male 33.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 190.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 190.0
Samples: 4

Max nTPM: 195.8
Min nTPM: 184.0
Sample A Male 187.0
Sample B Male 184.0
Sample C Female 195.8
Sample D Female 193.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.7
69262253 Antisense, RP_050301_02_A01, Mouse strain C57BL/6J (56 days, male) 9.9
73769326 Antisense, RP_051121_04_B11, Mouse strain C57BL/6J (56 days, male) 9.6

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