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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:129.9 nTPM
HPA:129.9 nTPM
GTEx:111.1 nTPM
FANTOM5:49.0 Scaled Tags Per Million
Pig:54.1 nTPM
Mouse:88.5 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 129.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 124.3
2019 Male, age 18, unknown 133.7
2411 Female, age 72, unknown 131.9
2586 Male, age 75, left hemisphere 127.7
2828 Female, age 72, unknown 125.5
1827 Male, age 72, unknown 122.7
1870 Female, age 42, unknown 122.7
1833 Male, age 53, unknown 120.9
1830 Male, age 51, unknown 120.4
2219 Male, age 76, both hemispheres 119.6
2666 Male, age 74, left hemisphere 118.3
Dorsal raphe nucleus
nTPM: 129.9
2298 Female, age 72, unknown 135.9
2047 Male, age 72, unknown 130.8
2750 Male, age 76, both hemispheres 130.4
1828 Male, age 53, unknown 128.6
2016 Female, age 72, unknown 123.8
Inferior colliculus
nTPM: 121.4
2097 Female, age 72, unknown 127.9
1890 Male, age 53, unknown 123.7
1848 Female, age 42, unknown 119.5
2849 Male, age 72, unknown 114.4
Median raphe nucleus
nTPM: 125.5
2220 Male, age 76, midline 125.5
Pedunculopontine tegmental nucleus
nTPM: 122.2
1921 Female, age 85, both hemispheres 125.3
2334 Male, age 80, both hemispheres 122.7
2338 Male, age 61, both hemispheres 118.5
Periaquaductal grey, anterior
nTPM: 121.8
1795 Male, age 51, unknown 124.4
2502 Female, age 75, unknown 121.5
1947 Male, age 18, unknown 119.3
Periaquaductal grey, dorsal
nTPM: 118.9
2464 Female, age 72, unknown 122.6
1840 Male, age 53, unknown 119.6
1831 Male, age 72, unknown 118.3
2850 Male, age 76, both hemispheres 115.2
Periaquaductal grey, lateral
nTPM: 119.2
2272 Male, age 74, both hemispheres 123.4
2053 Male, age 18, unknown 118.8
2140 Male, age 76, both hemispheres 115.4
Pretectal area
nTPM: 125.5
1817 Female, age 42, unknown 134.5
2007 Male, age 72, unknown 132.2
2667 Female, age 75, unknown 129.1
1816 Male, age 51, unknown 128.0
1944 Female, age 72, unknown 126.7
2273 Male, age 74, both hemispheres 126.2
1815 Male, age 53, unknown 125.6
2224 Female, age 72, unknown 122.9
2825 Male, age 18, unknown 119.4
2316 Male, age 76, right hemisphere 118.6
2407 Male, age 75, both hemispheres 117.4
Red nucleus
nTPM: 126.1
1821 Female, age 72, unknown 132.0
2503 Female, age 72, unknown 129.2
1904 Male, age 53, unknown 128.4
2785 Male, age 18, unknown 127.4
2769 Male, age 72, unknown 126.7
2227 Male, age 72, unknown 126.5
2725 Female, age 75, unknown 126.4
1954 Female, age 42, unknown 126.0
1865 Male, age 51, unknown 123.8
2823 Male, age 76, right hemisphere 123.4
2588 Male, age 74, left hemisphere 123.1
2584 Male, age 75, left hemisphere 119.8
Substantia nigra
nTPM: 127.8
1916 Female, age 42, unknown 134.8
1851 Male, age 51, unknown 133.4
2409 Female, age 72, unknown 131.3
1889 Female, age 72, unknown 130.9
2241 Male, age 72, unknown 129.4
1941 Male, age 53, unknown 126.0
2699 Male, age 18, unknown 124.8
2590 Female, age 75, unknown 123.5
2583 Male, age 75, right hemisphere 123.3
2665 Male, age 74, both hemispheres 120.5
Superior colliculus
nTPM: 122.3
2087 Female, age 72, unknown 127.9
1796 Male, age 53, unknown 124.1
2261 Male, age 18, unknown 123.8
2587 Male, age 74, left hemisphere 123.4
1995 Male, age 72, unknown 122.2
2668 Female, age 75, unknown 122.1
1913 Female, age 42, unknown 121.8
2664 Male, age 75, both hemispheres 120.0
1839 Male, age 51, unknown 119.4
1895 Male, age 76, right hemisphere 118.6
Ventral tegmental area
nTPM: 127.0
2410 Female, age 72, unknown 133.3
1915 Female, age 42, unknown 129.6
2223 Female, age 72, unknown 126.8
1942 Male, age 51, unknown 125.2
2021 Male, age 53, unknown 123.7
2218 Male, age 76, both hemispheres 123.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 111.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 111.1
Samples: 139

Max nTPM: 373.6
Min nTPM: 51.9
Std nTPM: 38.1
Median nTPM: 101.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 373.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 280.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 232.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 207.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 184.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 181.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 177.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 165.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 164.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 153.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 153.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 153.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 152.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 151.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 145.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 140.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 138.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 138.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 136.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 134.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 133.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 132.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 130.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 130.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 130.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 129.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 127.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 126.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 125.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 124.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 123.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 122.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 121.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 121.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 120.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 119.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 119.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 118.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 117.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 116.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 116.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 115.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 114.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 113.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 112.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 111.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 111.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 111.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 111.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 111.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 110.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 110.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 110.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 109.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 109.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 109.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 109.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 107.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 107.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 106.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 106.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 105.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 105.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 104.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 104.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 104.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 103.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 102.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 101.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 101.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 101.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 100.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 100.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 100.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 99.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 99.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 99.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 99.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 98.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 98.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 98.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 98.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 98.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 97.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 96.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 96.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 96.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 96.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 95.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 95.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 94.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 94.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 94.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 94.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 94.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 94.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 93.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 93.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 93.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 92.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 92.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 91.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 90.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 90.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 90.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 90.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 89.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 89.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 89.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 89.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 89.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 87.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 87.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 87.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 86.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 85.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 84.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 83.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 82.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 82.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 82.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 82.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 80.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 79.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 79.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 78.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 77.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 76.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 76.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 75.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 74.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 72.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 71.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 70.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 60.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 51.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 49.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 49.0
FF:10158-103A5 76 years, female 49.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.1
Pig sample Sample description nTPM
Midbrain
nTPM: 54.1
Samples: 4

Max nTPM: 70.5
Min nTPM: 40.7
Sample A Female 70.5
Sample B Female 51.8
Sample C Male 53.3
Sample D Male 40.7
Periaqueductal gray
nTPM: 43.6
Samples: 3

Max nTPM: 46.6
Min nTPM: 38.1
Sample B Female 46.2
Sample C Male 46.6
Sample D Male 38.1
Substantia nigra
nTPM: 50.2
Samples: 4

Max nTPM: 71.2
Min nTPM: 42.4
Sample A Female 71.2
Sample B Female 44.2
Sample C Male 42.9
Sample D Male 42.4
Superior colliculi
nTPM: 53.8
Samples: 4

Max nTPM: 69.9
Min nTPM: 45.2
Sample A Female 69.9
Sample B Female 50.8
Sample C Male 49.3
Sample D Male 45.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 88.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 88.5
Samples: 4

Max nTPM: 99.8
Min nTPM: 82.3
Sample A Male 99.8
Sample B Male 82.6
Sample C Female 82.3
Sample D Female 89.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
69671869 Antisense, RP_050428_02_E06, Mouse strain C57BL/6J (56 days, male) 1.6

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