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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:21.3 nTPM
HPA:21.3 nTPM
GTEx:18.1 nTPM
FANTOM5:70.4 Scaled Tags Per Million
Pig:36.2 nTPM
Mouse:51.0 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 21.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 15.8
1870 Female, age 42, unknown 17.7
1827 Male, age 72, unknown 17.1
2411 Female, age 72, unknown 17.1
2019 Male, age 18, unknown 16.4
1833 Male, age 53, unknown 15.8
2219 Male, age 76, both hemispheres 15.4
1830 Male, age 51, unknown 15.2
2586 Male, age 75, left hemisphere 15.0
2828 Female, age 72, unknown 14.3
2666 Male, age 74, left hemisphere 14.1
Dorsal raphe nucleus
nTPM: 17.9
2298 Female, age 72, unknown 21.1
1828 Male, age 53, unknown 17.8
2047 Male, age 72, unknown 17.2
2750 Male, age 76, both hemispheres 17.1
2016 Female, age 72, unknown 16.2
Inferior colliculus
nTPM: 17.2
2097 Female, age 72, unknown 21.0
1848 Female, age 42, unknown 16.4
1890 Male, age 53, unknown 16.4
2849 Male, age 72, unknown 15.1
Median raphe nucleus
nTPM: 21.3
2220 Male, age 76, midline 21.3
Pedunculopontine tegmental nucleus
nTPM: 17.5
2334 Male, age 80, both hemispheres 19.4
1921 Female, age 85, both hemispheres 17.7
2338 Male, age 61, both hemispheres 15.6
Periaquaductal grey, anterior
nTPM: 18.4
2502 Female, age 75, unknown 19.2
1947 Male, age 18, unknown 19.1
1795 Male, age 51, unknown 16.9
Periaquaductal grey, dorsal
nTPM: 18.0
2850 Male, age 76, both hemispheres 20.1
1831 Male, age 72, unknown 17.4
1840 Male, age 53, unknown 17.4
2464 Female, age 72, unknown 17.1
Periaquaductal grey, lateral
nTPM: 16.9
2140 Male, age 76, both hemispheres 18.7
2053 Male, age 18, unknown 16.1
2272 Male, age 74, both hemispheres 15.8
Pretectal area
nTPM: 17.6
1816 Male, age 51, unknown 19.2
2224 Female, age 72, unknown 19.1
1944 Female, age 72, unknown 18.6
2007 Male, age 72, unknown 18.4
2273 Male, age 74, both hemispheres 18.2
1817 Female, age 42, unknown 17.9
1815 Male, age 53, unknown 17.7
2667 Female, age 75, unknown 17.2
2825 Male, age 18, unknown 16.5
2316 Male, age 76, right hemisphere 16.3
2407 Male, age 75, both hemispheres 14.8
Red nucleus
nTPM: 15.7
1821 Female, age 72, unknown 17.8
2725 Female, age 75, unknown 17.3
1954 Female, age 42, unknown 16.6
2785 Male, age 18, unknown 16.0
1904 Male, age 53, unknown 15.8
2503 Female, age 72, unknown 15.8
2227 Male, age 72, unknown 15.5
1865 Male, age 51, unknown 15.3
2769 Male, age 72, unknown 15.2
2584 Male, age 75, left hemisphere 14.7
2823 Male, age 76, right hemisphere 14.7
2588 Male, age 74, left hemisphere 14.1
Substantia nigra
nTPM: 17.8
2241 Male, age 72, unknown 22.1
1916 Female, age 42, unknown 19.8
1941 Male, age 53, unknown 18.9
1889 Female, age 72, unknown 18.8
1851 Male, age 51, unknown 18.4
2409 Female, age 72, unknown 17.8
2699 Male, age 18, unknown 16.1
2583 Male, age 75, right hemisphere 15.6
2590 Female, age 75, unknown 15.3
2665 Male, age 74, both hemispheres 15.2
Superior colliculus
nTPM: 16.0
2087 Female, age 72, unknown 17.7
2261 Male, age 18, unknown 17.4
2587 Male, age 74, left hemisphere 16.3
2668 Female, age 75, unknown 16.3
1796 Male, age 53, unknown 16.2
1839 Male, age 51, unknown 16.1
1895 Male, age 76, right hemisphere 15.9
1913 Female, age 42, unknown 15.7
1995 Male, age 72, unknown 14.5
2664 Male, age 75, both hemispheres 14.0
Ventral tegmental area
nTPM: 17.4
2410 Female, age 72, unknown 18.4
1915 Female, age 42, unknown 18.3
1942 Male, age 51, unknown 17.5
2218 Male, age 76, both hemispheres 17.3
2021 Male, age 53, unknown 16.6
2223 Female, age 72, unknown 16.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 18.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 18.1
Samples: 139

Max nTPM: 33.4
Min nTPM: 8.0
Std nTPM: 5.1
Median nTPM: 17.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 33.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 32.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 30.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 29.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 29.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 29.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 29.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 27.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 27.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 27.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 27.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 27.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 26.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 26.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 25.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 25.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 25.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 25.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 24.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 24.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 23.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 23.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 23.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 22.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 22.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 22.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 22.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 21.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 21.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 21.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 21.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 21.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 20.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 20.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 20.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 20.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 20.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 20.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 20.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 20.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 20.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 19.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 19.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 19.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 19.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 19.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 19.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 18.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 18.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 18.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 18.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 18.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 18.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 18.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 18.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 18.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 18.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 18.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 17.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 17.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 17.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 17.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 17.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 17.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 17.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 17.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 17.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 17.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 17.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 17.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 17.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 17.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 16.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 16.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 16.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 16.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 16.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 16.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 16.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 16.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 16.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 16.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 16.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 15.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 15.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 15.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 15.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 15.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 15.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 15.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 15.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 15.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 15.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 15.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 15.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 15.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 15.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 15.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 15.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 14.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 14.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 14.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 14.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 14.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 14.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 14.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 14.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 14.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 13.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 13.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 13.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 13.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 13.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 13.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 13.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 13.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 13.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 13.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 12.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 12.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 12.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 12.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 12.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 11.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 11.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 11.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 10.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 10.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 10.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 10.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 10.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 10.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 9.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 9.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 8.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 8.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 70.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 70.4
FF:10158-103A5 76 years, female 70.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 36.2
Pig sample Sample description nTPM
Midbrain
nTPM: 36.2
Samples: 4

Max nTPM: 48.4
Min nTPM: 30.0
Sample A Female 48.4
Sample B Female 32.7
Sample C Male 33.7
Sample D Male 30.0
Periaqueductal gray
nTPM: 28.6
Samples: 3

Max nTPM: 29.1
Min nTPM: 28.0
Sample B Female 28.7
Sample C Male 28.0
Sample D Male 29.1
Substantia nigra
nTPM: 32.2
Samples: 4

Max nTPM: 39.5
Min nTPM: 26.3
Sample A Female 39.5
Sample B Female 26.3
Sample C Male 33.9
Sample D Male 29.1
Superior colliculi
nTPM: 33.1
Samples: 4

Max nTPM: 38.1
Min nTPM: 29.1
Sample A Female 38.1
Sample B Female 29.1
Sample C Male 32.2
Sample D Male 32.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 51.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 51.0
Samples: 4

Max nTPM: 52.3
Min nTPM: 50.0
Sample A Male 50.0
Sample B Male 52.3
Sample C Female 50.0
Sample D Female 51.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
77454993 Antisense, RP_070129_01_F01, Mouse strain C57BL/6J (56 days, male) 0.1

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