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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:42.9 nTPM
HPA:42.9 nTPM
GTEx:49.5 nTPM
FANTOM5:57.2 Scaled Tags Per Million
Pig:38.0 nTPM
Mouse:60.8 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 42.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 39.9
1870 Female, age 42, unknown 44.2
1830 Male, age 51, unknown 43.0
1833 Male, age 53, unknown 41.8
2666 Male, age 74, left hemisphere 41.8
2411 Female, age 72, unknown 41.7
2019 Male, age 18, unknown 39.1
2586 Male, age 75, left hemisphere 37.6
2828 Female, age 72, unknown 37.2
2219 Male, age 76, both hemispheres 36.7
1827 Male, age 72, unknown 36.3
Dorsal raphe nucleus
nTPM: 37.2
2750 Male, age 76, both hemispheres 41.3
2016 Female, age 72, unknown 37.2
1828 Male, age 53, unknown 37.0
2047 Male, age 72, unknown 35.9
2298 Female, age 72, unknown 34.3
Inferior colliculus
nTPM: 36.4
1890 Male, age 53, unknown 37.8
1848 Female, age 42, unknown 37.4
2849 Male, age 72, unknown 35.2
2097 Female, age 72, unknown 35.0
Median raphe nucleus
nTPM: 38.3
2220 Male, age 76, midline 38.3
Pedunculopontine tegmental nucleus
nTPM: 39.4
2338 Male, age 61, both hemispheres 42.4
2334 Male, age 80, both hemispheres 39.7
1921 Female, age 85, both hemispheres 36.1
Periaquaductal grey, anterior
nTPM: 35.8
1947 Male, age 18, unknown 37.1
2502 Female, age 75, unknown 37.1
1795 Male, age 51, unknown 33.1
Periaquaductal grey, dorsal
nTPM: 35.6
1831 Male, age 72, unknown 38.0
2464 Female, age 72, unknown 35.7
2850 Male, age 76, both hemispheres 35.0
1840 Male, age 53, unknown 33.8
Periaquaductal grey, lateral
nTPM: 33.5
2053 Male, age 18, unknown 34.5
2272 Male, age 74, both hemispheres 33.0
2140 Male, age 76, both hemispheres 32.8
Pretectal area
nTPM: 35.5
1815 Male, age 53, unknown 38.8
2316 Male, age 76, right hemisphere 37.5
2407 Male, age 75, both hemispheres 37.2
2007 Male, age 72, unknown 36.4
2825 Male, age 18, unknown 36.4
1817 Female, age 42, unknown 35.8
1944 Female, age 72, unknown 34.4
2224 Female, age 72, unknown 34.3
1816 Male, age 51, unknown 33.7
2667 Female, age 75, unknown 33.5
2273 Male, age 74, both hemispheres 32.7
Red nucleus
nTPM: 42.9
1821 Female, age 72, unknown 45.6
1865 Male, age 51, unknown 45.5
2503 Female, age 72, unknown 45.3
1904 Male, age 53, unknown 44.7
2823 Male, age 76, right hemisphere 44.1
1954 Female, age 42, unknown 43.6
2588 Male, age 74, left hemisphere 43.1
2227 Male, age 72, unknown 42.5
2769 Male, age 72, unknown 41.7
2785 Male, age 18, unknown 41.5
2725 Female, age 75, unknown 39.9
2584 Male, age 75, left hemisphere 37.0
Substantia nigra
nTPM: 38.3
1851 Male, age 51, unknown 40.2
2699 Male, age 18, unknown 40.1
2409 Female, age 72, unknown 39.3
2590 Female, age 75, unknown 38.9
2665 Male, age 74, both hemispheres 38.7
1889 Female, age 72, unknown 38.5
2241 Male, age 72, unknown 38.0
2583 Male, age 75, right hemisphere 37.3
1941 Male, age 53, unknown 36.1
1916 Female, age 42, unknown 35.8
Superior colliculus
nTPM: 37.8
1913 Female, age 42, unknown 42.4
1995 Male, age 72, unknown 41.2
2587 Male, age 74, left hemisphere 40.3
2668 Female, age 75, unknown 40.2
1839 Male, age 51, unknown 38.3
1895 Male, age 76, right hemisphere 38.3
2664 Male, age 75, both hemispheres 35.3
1796 Male, age 53, unknown 34.2
2087 Female, age 72, unknown 34.2
2261 Male, age 18, unknown 33.8
Ventral tegmental area
nTPM: 39.1
2223 Female, age 72, unknown 41.4
2410 Female, age 72, unknown 40.5
2021 Male, age 53, unknown 38.8
1915 Female, age 42, unknown 38.4
2218 Male, age 76, both hemispheres 38.4
1942 Male, age 51, unknown 37.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 49.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 49.5
Samples: 139

Max nTPM: 104.7
Min nTPM: 23.5
Std nTPM: 16.8
Median nTPM: 46.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 104.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 103.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 97.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 96.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 90.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 83.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 83.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 82.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 81.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 80.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 80.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 79.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 76.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 71.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 70.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 70.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 68.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 68.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 67.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 66.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 64.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 63.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 62.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 61.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 60.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 60.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 60.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 60.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 60.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 59.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 59.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 57.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 57.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 57.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 57.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 56.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 56.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 56.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 55.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 55.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 54.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 54.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 53.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 53.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 53.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 53.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 52.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 51.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 50.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 50.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 50.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 49.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 49.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 49.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 48.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 48.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 48.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 48.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 47.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 47.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 46.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 46.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 46.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 45.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 45.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 45.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 45.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 45.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 44.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 44.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 43.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 43.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 43.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 43.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 43.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 43.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 42.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 42.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 41.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 41.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 40.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 39.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 39.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 39.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 38.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 38.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 38.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 37.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 37.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 37.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 36.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 36.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 35.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 35.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 35.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 35.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 34.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 34.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 34.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 34.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 34.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 34.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 34.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 33.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 33.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 32.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 32.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 32.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 32.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 31.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 31.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 31.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 31.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 31.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 30.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 30.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 30.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 30.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 30.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 29.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 29.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 28.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 28.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 28.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 27.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 27.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 27.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 23.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 57.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 57.2
FF:10158-103A5 76 years, female 57.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 38.0
Pig sample Sample description nTPM
Midbrain
nTPM: 35.0
Samples: 4

Max nTPM: 48.8
Min nTPM: 25.6
Sample A Female 48.8
Sample B Female 39.7
Sample C Male 25.9
Sample D Male 25.6
Periaqueductal gray
nTPM: 29.5
Samples: 3

Max nTPM: 31.2
Min nTPM: 28.0
Sample B Female 29.2
Sample C Male 28.0
Sample D Male 31.2
Substantia nigra
nTPM: 38.0
Samples: 4

Max nTPM: 43.3
Min nTPM: 35.4
Sample A Female 43.3
Sample B Female 36.1
Sample C Male 37.1
Sample D Male 35.4
Superior colliculi
nTPM: 31.5
Samples: 4

Max nTPM: 33.0
Min nTPM: 30.0
Sample A Female 33.0
Sample B Female 30.0
Sample C Male 31.2
Sample D Male 31.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 60.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 60.8
Samples: 4

Max nTPM: 65.8
Min nTPM: 57.1
Sample A Male 57.1
Sample B Male 59.0
Sample C Female 65.8
Sample D Female 61.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
69117026 Antisense, RP_050321_01_F02, Mouse strain C57BL/6J (56 days, male) 0.6

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