P02649 [Direct mapping]
Apolipoprotein E
A0A0S2Z3D5 [Target identity:100%; Query identity:100%]
Apolipoprotein E isoform 1

GO:0000302 [response to reactive oxygen species]
GO:0001523 [retinoid metabolic process]
GO:0001540 [amyloid-beta binding]
GO:0001937 [negative regulation of endothelial cell proliferation]
GO:0002021 [response to dietary excess]
GO:0005102 [signaling receptor binding]
GO:0005198 [structural molecule activity]
GO:0005319 [lipid transporter activity]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005788 [endoplasmic reticulum lumen]
GO:0005794 [Golgi apparatus]
GO:0005886 [plasma membrane]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0006629 [lipid metabolic process]
GO:0006641 [triglyceride metabolic process]
GO:0006707 [cholesterol catabolic process]
GO:0006869 [lipid transport]
GO:0006874 [cellular calcium ion homeostasis]
GO:0006898 [receptor-mediated endocytosis]
GO:0006979 [response to oxidative stress]
GO:0007010 [cytoskeleton organization]
GO:0007186 [G protein-coupled receptor signaling pathway]
GO:0007263 [nitric oxide mediated signal transduction]
GO:0007271 [synaptic transmission, cholinergic]
GO:0007616 [long-term memory]
GO:0008201 [heparin binding]
GO:0008202 [steroid metabolic process]
GO:0008203 [cholesterol metabolic process]
GO:0008289 [lipid binding]
GO:0010467 [gene expression]
GO:0010468 [regulation of gene expression]
GO:0010544 [negative regulation of platelet activation]
GO:0010596 [negative regulation of endothelial cell migration]
GO:0010629 [negative regulation of gene expression]
GO:0010873 [positive regulation of cholesterol esterification]
GO:0010875 [positive regulation of cholesterol efflux]
GO:0010877 [lipid transport involved in lipid storage]
GO:0010976 [positive regulation of neuron projection development]
GO:0010977 [negative regulation of neuron projection development]
GO:0015909 [long-chain fatty acid transport]
GO:0016020 [membrane]
GO:0016209 [antioxidant activity]
GO:0017038 [protein import]
GO:0019068 [virion assembly]
GO:0019934 [cGMP-mediated signaling]
GO:0030195 [negative regulation of blood coagulation]
GO:0030425 [dendrite]
GO:0030516 [regulation of axon extension]
GO:0030669 [clathrin-coated endocytic vesicle membrane]
GO:0031012 [extracellular matrix]
GO:0031175 [neuron projection development]
GO:0032269 [negative regulation of cellular protein metabolic process]
GO:0032489 [regulation of Cdc42 protein signal transduction]
GO:0032805 [positive regulation of low-density lipoprotein particle receptor catabolic process]
GO:0033344 [cholesterol efflux]
GO:0033700 [phospholipid efflux]
GO:0034361 [very-low-density lipoprotein particle]
GO:0034362 [low-density lipoprotein particle]
GO:0034363 [intermediate-density lipoprotein particle]
GO:0034364 [high-density lipoprotein particle]
GO:0034365 [discoidal high-density lipoprotein particle]
GO:0034371 [chylomicron remodeling]
GO:0034372 [very-low-density lipoprotein particle remodeling]
GO:0034374 [low-density lipoprotein particle remodeling]
GO:0034375 [high-density lipoprotein particle remodeling]
GO:0034378 [chylomicron assembly]
GO:0034380 [high-density lipoprotein particle assembly]
GO:0034382 [chylomicron remnant clearance]
GO:0034384 [high-density lipoprotein particle clearance]
GO:0034447 [very-low-density lipoprotein particle clearance]
GO:0035641 [locomotory exploration behavior]
GO:0042157 [lipoprotein metabolic process]
GO:0042158 [lipoprotein biosynthetic process]
GO:0042159 [lipoprotein catabolic process]
GO:0042311 [vasodilation]
GO:0042627 [chylomicron]
GO:0042632 [cholesterol homeostasis]
GO:0042802 [identical protein binding]
GO:0042803 [protein homodimerization activity]
GO:0042981 [regulation of apoptotic process]
GO:0042982 [amyloid precursor protein metabolic process]
GO:0043025 [neuronal cell body]
GO:0043083 [synaptic cleft]
GO:0043254 [regulation of protein-containing complex assembly]
GO:0043395 [heparan sulfate proteoglycan binding]
GO:0043407 [negative regulation of MAP kinase activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043537 [negative regulation of blood vessel endothelial cell migration]
GO:0043687 [post-translational protein modification]
GO:0043691 [reverse cholesterol transport]
GO:0044267 [cellular protein metabolic process]
GO:0044794 [positive regulation by host of viral process]
GO:0044877 [protein-containing complex binding]
GO:0045088 [regulation of innate immune response]
GO:0045541 [negative regulation of cholesterol biosynthetic process]
GO:0045807 [positive regulation of endocytosis]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0046889 [positive regulation of lipid biosynthetic process]
GO:0046907 [intracellular transport]
GO:0046911 [metal chelating activity]
GO:0046983 [protein dimerization activity]
GO:0048156 [tau protein binding]
GO:0048168 [regulation of neuronal synaptic plasticity]
GO:0048844 [artery morphogenesis]
GO:0050709 [negative regulation of protein secretion]
GO:0050728 [negative regulation of inflammatory response]
GO:0050750 [low-density lipoprotein particle receptor binding]
GO:0050790 [regulation of catalytic activity]
GO:0050807 [regulation of synapse organization]
GO:0051000 [positive regulation of nitric-oxide synthase activity]
GO:0051044 [positive regulation of membrane protein ectodomain proteolysis]
GO:0051246 [regulation of protein metabolic process]
GO:0051651 [maintenance of location in cell]
GO:0055088 [lipid homeostasis]
GO:0055089 [fatty acid homeostasis]
GO:0060228 [phosphatidylcholine-sterol O-acyltransferase activator activity]
GO:0060999 [positive regulation of dendritic spine development]
GO:0061136 [regulation of proteasomal protein catabolic process]
GO:0061771 [response to caloric restriction]
GO:0062023 [collagen-containing extracellular matrix]
GO:0070062 [extracellular exosome]
GO:0070326 [very-low-density lipoprotein particle receptor binding]
GO:0070328 [triglyceride homeostasis]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
GO:0071682 [endocytic vesicle lumen]
GO:0071813 [lipoprotein particle binding]
GO:0071830 [triglyceride-rich lipoprotein particle clearance]
GO:0071831 [intermediate-density lipoprotein particle clearance]
GO:0072359 [circulatory system development]
GO:0072562 [blood microparticle]
GO:0090090 [negative regulation of canonical Wnt signaling pathway]
GO:0090181 [regulation of cholesterol metabolic process]
GO:0090209 [negative regulation of triglyceride metabolic process]
GO:0097006 [regulation of plasma lipoprotein particle levels]
GO:0097113 [AMPA glutamate receptor clustering]
GO:0097114 [NMDA glutamate receptor clustering]
GO:0098869 [cellular oxidant detoxification]
GO:0098978 [glutamatergic synapse]
GO:0120009 [intermembrane lipid transfer]
GO:0120020 [cholesterol transfer activity]
GO:1900221 [regulation of amyloid-beta clearance]
GO:1900223 [positive regulation of amyloid-beta clearance]
GO:1900272 [negative regulation of long-term synaptic potentiation]
GO:1902430 [negative regulation of amyloid-beta formation]
GO:1902952 [positive regulation of dendritic spine maintenance]
GO:1902991 [regulation of amyloid precursor protein catabolic process]
GO:1902995 [positive regulation of phospholipid efflux]
GO:1903002 [positive regulation of lipid transport across blood-brain barrier]
GO:1903561 [extracellular vesicle]
GO:1905855 [positive regulation of heparan sulfate binding]
GO:1905860 [positive regulation of heparan sulfate proteoglycan binding]
GO:1905890 [regulation of cellular response to very-low-density lipoprotein particle stimulus]
GO:1905906 [regulation of amyloid fibril formation]
GO:1905907 [negative regulation of amyloid fibril formation]
GO:1905908 [positive regulation of amyloid fibril formation]
GO:1990777 [lipoprotein particle]
GO:2000822 [regulation of behavioral fear response]

H0Y7L5 [Direct mapping]
Apolipoprotein E

GO:0005576 [extracellular region]
GO:0006869 [lipid transport]
GO:0008289 [lipid binding]
GO:0034364 [high-density lipoprotein particle]
GO:0042157 [lipoprotein metabolic process]