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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:301.7 nTPM
HPA:301.7 nTPM
GTEx:130.8 nTPM
FANTOM5:33.2 Scaled Tags Per Million
Pig:159.9 nTPM
Mouse:165.2 nTPM
Allen mouse:10.5 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 301.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 285.9
2586 Male, age 75, left hemisphere 343.6
2219 Male, age 76, both hemispheres 296.7
2019 Male, age 18, unknown 290.4
1827 Male, age 72, unknown 284.7
2828 Female, age 72, unknown 281.6
2666 Male, age 74, left hemisphere 278.6
2411 Female, age 72, unknown 274.4
1833 Male, age 53, unknown 271.3
1870 Female, age 42, unknown 269.2
1830 Male, age 51, unknown 268.7
Dorsal raphe nucleus
nTPM: 281.1
2298 Female, age 72, unknown 286.2
1828 Male, age 53, unknown 285.3
2047 Male, age 72, unknown 282.6
2016 Female, age 72, unknown 277.3
2750 Male, age 76, both hemispheres 274.1
Inferior colliculus
nTPM: 289.5
2097 Female, age 72, unknown 311.5
1890 Male, age 53, unknown 298.4
1848 Female, age 42, unknown 278.1
2849 Male, age 72, unknown 270.0
Median raphe nucleus
nTPM: 279.0
2220 Male, age 76, midline 279.0
Pedunculopontine tegmental nucleus
nTPM: 276.3
1921 Female, age 85, both hemispheres 288.5
2334 Male, age 80, both hemispheres 282.4
2338 Male, age 61, both hemispheres 257.8
Periaquaductal grey, anterior
nTPM: 293.6
1795 Male, age 51, unknown 312.6
2502 Female, age 75, unknown 288.6
1947 Male, age 18, unknown 279.6
Periaquaductal grey, dorsal
nTPM: 278.6
1831 Male, age 72, unknown 298.4
1840 Male, age 53, unknown 273.7
2464 Female, age 72, unknown 271.4
2850 Male, age 76, both hemispheres 271.0
Periaquaductal grey, lateral
nTPM: 276.0
2053 Male, age 18, unknown 282.6
2272 Male, age 74, both hemispheres 275.0
2140 Male, age 76, both hemispheres 270.4
Pretectal area
nTPM: 301.7
1816 Male, age 51, unknown 340.4
1944 Female, age 72, unknown 333.0
2667 Female, age 75, unknown 320.1
2007 Male, age 72, unknown 318.2
1817 Female, age 42, unknown 312.3
1815 Male, age 53, unknown 301.6
2224 Female, age 72, unknown 283.7
2273 Male, age 74, both hemispheres 280.8
2407 Male, age 75, both hemispheres 280.4
2825 Male, age 18, unknown 276.7
2316 Male, age 76, right hemisphere 271.2
Red nucleus
nTPM: 274.1
2785 Male, age 18, unknown 294.9
2584 Male, age 75, left hemisphere 285.4
2588 Male, age 74, left hemisphere 278.7
2725 Female, age 75, unknown 278.3
1821 Female, age 72, unknown 273.7
1954 Female, age 42, unknown 273.7
1904 Male, age 53, unknown 269.4
2503 Female, age 72, unknown 269.2
2227 Male, age 72, unknown 269.1
2769 Male, age 72, unknown 267.8
1865 Male, age 51, unknown 267.7
2823 Male, age 76, right hemisphere 261.9
Substantia nigra
nTPM: 299.6
2665 Male, age 74, both hemispheres 337.4
2583 Male, age 75, right hemisphere 315.0
1889 Female, age 72, unknown 303.1
1916 Female, age 42, unknown 301.4
1941 Male, age 53, unknown 301.0
1851 Male, age 51, unknown 295.4
2241 Male, age 72, unknown 293.7
2590 Female, age 75, unknown 293.6
2409 Female, age 72, unknown 280.9
2699 Male, age 18, unknown 274.4
Superior colliculus
nTPM: 290.0
2087 Female, age 72, unknown 312.0
2261 Male, age 18, unknown 310.6
2664 Male, age 75, both hemispheres 306.4
1796 Male, age 53, unknown 306.0
1995 Male, age 72, unknown 285.9
1913 Female, age 42, unknown 281.5
2587 Male, age 74, left hemisphere 277.7
1839 Male, age 51, unknown 274.6
2668 Female, age 75, unknown 274.0
1895 Male, age 76, right hemisphere 271.5
Ventral tegmental area
nTPM: 294.1
2223 Female, age 72, unknown 315.4
1942 Male, age 51, unknown 293.3
2218 Male, age 76, both hemispheres 293.1
2410 Female, age 72, unknown 292.7
1915 Female, age 42, unknown 289.1
2021 Male, age 53, unknown 281.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 130.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 130.8
Samples: 139

Max nTPM: 282.9
Min nTPM: 24.3
Std nTPM: 46.7
Median nTPM: 130.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 282.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 255.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 243.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 233.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 214.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 202.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 202.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 200.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 200.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 198.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 198.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 197.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 197.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 196.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 194.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 192.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 192.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 189.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 183.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 182.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 181.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 180.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 177.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 176.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 175.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 169.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 168.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 168.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 168.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 165.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 164.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 163.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 163.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 162.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 160.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 157.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 157.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 156.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 153.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 153.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 152.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 149.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 148.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 148.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 147.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 147.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 146.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 146.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 145.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 145.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 144.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 144.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 144.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 144.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 143.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 143.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 143.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 142.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 142.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 141.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 140.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 139.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 138.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 137.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 137.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 135.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 134.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 134.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 131.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 130.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 129.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 127.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 126.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 126.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 125.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 123.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 122.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 121.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 118.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 118.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 118.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 117.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 116.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 115.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 115.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 114.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 114.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 114.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 113.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 113.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 110.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 109.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 108.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 106.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 106.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 104.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 104.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 101.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 100.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 99.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 98.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 96.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 94.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 93.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 92.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 92.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 92.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 91.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 87.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 87.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 82.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 81.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 81.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 79.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 78.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 78.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 75.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 74.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 74.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 74.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 72.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 70.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 70.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 69.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 69.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 67.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 67.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 66.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 66.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 66.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 60.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 55.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 48.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 28.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 24.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 33.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 33.2
FF:10158-103A5 76 years, female 33.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 159.9
Pig sample Sample description nTPM
Midbrain
nTPM: 159.9
Samples: 4

Max nTPM: 278.4
Min nTPM: 66.7
Sample A Female 80.9
Sample B Female 66.7
Sample C Male 278.4
Sample D Male 213.5
Periaqueductal gray
nTPM: 57.2
Samples: 3

Max nTPM: 70.0
Min nTPM: 47.8
Sample B Female 53.7
Sample C Male 70.0
Sample D Male 47.8
Substantia nigra
nTPM: 107.2
Samples: 4

Max nTPM: 131.0
Min nTPM: 80.8
Sample A Female 131.0
Sample B Female 93.8
Sample C Male 123.2
Sample D Male 80.8
Superior colliculi
nTPM: 139.6
Samples: 4

Max nTPM: 199.5
Min nTPM: 95.8
Sample A Female 143.9
Sample B Female 95.8
Sample C Male 199.5
Sample D Male 119.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 165.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 165.2
Samples: 4

Max nTPM: 174.9
Min nTPM: 157.6
Sample A Male 166.9
Sample B Male 161.4
Sample C Female 174.9
Sample D Female 157.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.5
760 Antisense, RP_040324_01_F03, Mouse strain C57BL/6J (56 days, male) 10.5
761 Antisense, RP_040324_01_F03, Mouse strain C57BL/6J (56 days, male) 9.0

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