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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA016488
Pigment epithelial cells
High
Photoreceptor cells
High
Limiting membrane
Not detected
Outer plexiform layer
High
Inner nuclear layer
Medium
Inner plexiform layer
Medium
Ganglion cells
Low
Nerve fiber layer
High
RETINA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 223.3
Min nTPM: 8.2
Std nTPM: 43.9
Median nTPM: 0.0
43_1
64 years, female
223.3
139_1
64 years, female
187.2
217_1
76 years, male
172.3
286_1
68 years, female
160.6
142_1
61 years, female
157.8
81_1
67 years, male
143.5
153_1
70 years, female
142.3
32_1
67 years, male
140.1
137_1
83 years, male
139.9
6_1
73 years, female
136.8
162_1
79 years, female
135.7
149_1
88 years, male
135.1
126_1
63 years, male
133.4
145_1
84 years, male
132.8
2_1
77 years, female
128.6
4_1
88 years, female
124.7
42_1
85 years, male
120.1
35_1
74 years, female
117.9
316_1
62 years, male
112.8
518_1
75 years, female
112.0
17_1
71 years, male
111.6
229_1
69 years, female
109.7
352_1
62 years, male
105.5
163_1
78 years, male
104.5
172_1
72 years, female
102.2
9_1
66 years, female
99.2
117_1
61 years, male
97.6
348_1
84 years, male
93.9
406_1
79 years, male
87.8
503_1
68 years, male
84.2
466_1
57 years, female
81.8
314_1
67 years, male
80.7
480_1
63 years, male
78.6
320_1
89 years, female
78.2
490_1
67 years, female
75.3
335_1
73 years, female
72.4
322_1
76 years, male
70.6
495_1
57 years, female
69.9
288_1
66 years, female
69.6
517_1
88 years, male
69.6
354_1
81 years, female
69.4
218_1
71 years, female
67.4
318_1
68 years, male
65.8
375_1
74 years, female
63.5
251_1
78 years, male
63.2
349_1
83 years, male
62.8
319_1
81 years, male
62.7
491_1
89 years, female
61.3
18_1
88 years, male
60.2
115_1
83 years, male
60.1
353_1
82 years, female
58.0
237_1
82 years, male
56.5
396_1
62 years, male
54.3
405_1
91 years, male
53.1
506_1
65 years, male
52.1
468_1
89 years, male
51.8
243_1
75 years, male
51.7
311_1
78 years, male
51.4
120_1
70 years, female
49.2
321_1
62 years, female
48.3
394_1
75 years, female
48.1
109_1
81 years, female
47.5
404_1
82 years, female
47.2
89_1
63 years, male
47.1
425_1
59 years, female
43.3
376_1
75 years, female
42.9
291_1
76 years, male
41.9
447_1
81 years, male
41.5
526_1
61 years, male
41.2
177_1
74 years, male
40.6
265_1
87 years, male
40.1
119_1
70 years, female
39.6
350_1
84 years, female
38.5
355_1
70 years, female
38.0
351_1
91 years, male
37.9
389_1
86 years, female
37.4
356_1
87 years, female
36.5
292_1
71 years, male
36.3
379_1
60 years, male
35.6
452_1
88 years, female
33.7
264_1
73 years, female
33.5
501_1
88 years, male
33.2
386_1
76 years, male
33.1
99_1
64 years, male
31.9
173_1
67 years, male
31.2
313_1
79 years, female
29.3
377_1
82 years, female
29.3
317_1
60 years, male
29.0
324_1
76 years, male
28.5
415_1
77 years, female
28.5
189_1
76 years, male
27.6
295_1
61 years, female
26.6
293_1
68 years, female
26.4
246_1
77 years, male
26.1
266_1
85 years, male
26.1
499_1
55 years, female
23.7
414_1
84 years, female
22.3
413_1
59 years, female
22.0
384_1
83 years, male
21.4
315_1
62 years, female
21.2
347_1
72 years, male
18.3
307_1
66 years, female
16.1
254_1
77 years, female
15.2
41_1
94 years, female
8.7
308_1
70 years, female
8.2
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
