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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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101.508
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:431.3 nTPM
HPA:431.3 nTPM
FANTOM5:2760.9 Scaled Tags Per Million
Pig:425.9 nTPM
Mouse:80.9 nTPM
Allen mouse:16.4 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA022275
Pons mean intensity 101.508
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

Read more
FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 38.662
Parabrachial nucleus 37.626
Principle sensory trigeminal nucleus 30.113
Locus coeruleus 84.648
Pontine nucleus 36.012
Vestibular nucleus 38.523
Pontine reticular nucleus, oral 14.131
Lateral lemniscus 18.579
Superior paraolivary nucleus 11.077

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 431.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 143.0
2301 Female, age 85, both hemispheres 174.4
2188 Female, age 91, both hemispheres 168.0
1984 Male, age 76, both hemispheres 155.0
2090 Male, age 80, both hemispheres 74.6
Area postrema
nTPM: 118.6
2799 Male, age 61, both hemispheres 172.1
2054 Male, age 76, both hemispheres 134.0
2306 Male, age 80, both hemispheres 49.6
Cuneate nuclei
nTPM: 161.1
2131 Male, age 76, both hemispheres 270.0
2376 Male, age 61, both hemispheres 133.6
2381 Male, age 80, both hemispheres 79.8
Dorsal cochlear nucleus
nTPM: 132.4
2187 Female, age 91, both hemispheres 200.3
2058 Male, age 76, both hemispheres 161.7
2802 Male, age 74, right hemisphere 161.2
2370 Male, age 61, both hemispheres 83.9
2378 Male, age 80, both hemispheres 54.9
Dorsal medullary reticular nucleus
nTPM: 193.1
2040 Female, age 85, both hemispheres 334.3
2088 Male, age 76, both hemispheres 141.2
2373 Male, age 61, both hemispheres 103.8
Dorsal motor vagal complex
nTPM: 182.3
2133 Female, age 91, both hemispheres 403.7
2000 Male, age 74, unknown 313.1
2844 Male, age 55, unknown 198.6
2643 Male, age 74, both hemispheres 188.1
2813 Female, age 72, unknown 182.2
2185 Male, age 76, both hemispheres 89.5
2797 Male, age 61, both hemispheres 72.5
2807 Female, age 85, both hemispheres 11.0
Dorsal tegmental nucleus
nTPM: 163.1
2083 Male, age 80, both hemispheres 200.6
2326 Male, age 74, both hemispheres 159.5
2358 Male, age 61, both hemispheres 154.7
1936 Male, age 76, left hemisphere 137.6
Dorsolateral tegmental area
nTPM: 127.4
2751 Female, age 85, both hemispheres 183.4
2654 Male, age 80, both hemispheres 175.5
2141 Male, age 76, both hemispheres 129.3
2360 Male, age 74, both hemispheres 95.2
2337 Male, age 61, both hemispheres 53.6
Gigantocellular reticular nuclei, medullary
nTPM: 180.2
2462 Male, age 74, both hemispheres 320.0
2314 Male, age 61, both hemispheres 178.1
2310 Male, age 80, both hemispheres 162.7
2022 Male, age 76, right hemisphere 153.6
1876 Female, age 85, both hemispheres 149.9
2387 Female, age 91, both hemispheres 117.1
Gigantocellular reticular nuclei, pars
nTPM: 219.0
2168 Male, age 76, both hemispheres 373.4
2084 Female, age 85, both hemispheres 236.6
2336 Male, age 61, both hemispheres 206.3
2330 Male, age 80, both hemispheres 147.3
2706 Male, age 80, both hemispheres 131.5
Inferior olive
nTPM: 158.8
2563 Male, age 74, both hemispheres 256.7
2085 Female, age 85, both hemispheres 236.3
2628 Female, age 91, both hemispheres 125.4
2178 Male, age 61, both hemispheres 108.8
2379 Male, age 80, both hemispheres 66.9
Kolliker-Fuse nucleus
nTPM: 213.4
2163 Male, age 80, both hemispheres 375.4
2793 Female, age 91, left hemisphere 168.9
2315 Male, age 76, right hemisphere 95.8
Lateral lemniscal nuclei
nTPM: 268.4
2169 Male, age 76, both hemispheres 391.2
2036 Male, age 80, both hemispheres 287.7
2453 Male, age 74, right hemisphere 264.0
2746 Female, age 85, left hemisphere 257.1
2320 Female, age 91, left hemisphere 142.1
Lateral medullary reticular nucleus
nTPM: 218.2
2044 Male, age 76, both hemispheres 331.2
2305 Male, age 74, both hemispheres 321.7
2804 Female, age 91, both hemispheres 204.0
2374 Male, age 61, both hemispheres 173.9
2190 Female, age 85, both hemispheres 171.4
2852 Male, age 80, both hemispheres 107.2
Lateral parabrachial nucleus
nTPM: 174.3
2139 Female, age 85, right hemisphere 300.3
2790 Male, age 61, both hemispheres 199.9
2013 Male, age 80, both hemispheres 152.9
2792 Male, age 76, both hemispheres 44.1
Lateral vestibular nucleus
nTPM: 269.5
2184 Male, age 76, both hemispheres 398.4
2311 Male, age 80, both hemispheres 140.5
Locus coeruleus
nTPM: 431.3
2123 Female, age 91, both hemispheres 673.2
2720 Male, age 74, both hemispheres 472.4
2014 Male, age 55, unknown 460.3
1980 Male, age 76, both hemispheres 417.1
2788 Male, age 74, unknown 387.1
2317 Female, age 72, unknown 327.8
2162 Male, age 80, both hemispheres 281.2
Medial olivary nucleus
nTPM: 98.1
2138 Female, age 91, both hemispheres 117.5
2851 Male, age 80, both hemispheres 110.1
1962 Male, age 76, both hemispheres 98.6
1943 Male, age 61, both hemispheres 66.1
Medial parabrachial nucleus
nTPM: 204.4
2170 Female, age 91, both hemispheres 258.7
2156 Male, age 61, both hemispheres 242.5
2854 Male, age 80, both hemispheres 214.1
2463 Female, age 85, right hemisphere 161.0
2786 Male, age 76, both hemispheres 145.7
Medial periolivary nuclei
nTPM: 260.2
2171 Female, age 85, both hemispheres 464.2
2063 Male, age 76, both hemispheres 401.2
2791 Male, age 74, right hemisphere 215.3
2458 Female, age 91, both hemispheres 122.7
2081 Male, age 80, both hemispheres 97.3
Medial vestibular nucleus
nTPM: 304.0
2134 Male, age 76, both hemispheres 438.8
2801 Male, age 74, both hemispheres 389.1
2624 Male, age 61, both hemispheres 311.8
2803 Female, age 91, both hemispheres 243.7
2743 Female, age 85, both hemispheres 234.6
2093 Male, age 80, both hemispheres 206.1
Motor facial nucleus
nTPM: 262.1
2062 Male, age 76, both hemispheres 440.7
2365 Male, age 74, right hemisphere 292.3
2697 Female, age 85, both hemispheres 263.3
2327 Male, age 80, both hemispheres 235.3
2126 Male, age 61, both hemispheres 185.0
2795 Female, age 91, both hemispheres 155.7
Motor hypoglossal nucleus
nTPM: 273.1
2461 Male, age 61, both hemispheres 491.7
2125 Female, age 91, both hemispheres 324.2
2132 Female, age 85, both hemispheres 270.9
2182 Male, age 80, both hemispheres 169.8
2277 Male, age 76, both hemispheres 109.1
Motor trigeminal nucleus
nTPM: 166.0
2079 Male, age 80, both hemispheres 246.3
2560 Male, age 74, both hemispheres 163.4
2309 Male, age 76, both hemispheres 145.8
2321 Female, age 91, both hemispheres 139.5
2335 Male, age 61, both hemispheres 134.9
Nuclei of the trapezoid body
nTPM: 339.5
2159 Male, age 61, both hemispheres 541.0
2735 Female, age 85, both hemispheres 409.3
1983 Male, age 76, both hemispheres 385.6
2166 Male, age 80, both hemispheres 211.7
2368 Female, age 91, both hemispheres 149.9
Nucleus ambiguus
nTPM: 168.3
2096 Female, age 85, both hemispheres 231.9
2071 Male, age 76, both hemispheres 104.7
Nucleus cuneatus
nTPM: 120.8
2564 Male, age 74, both hemispheres 234.4
2100 Male, age 76, both hemispheres 201.8
2562 Male, age 61, both hemispheres 92.7
2808 Female, age 85, both hemispheres 86.3
2380 Male, age 80, both hemispheres 54.9
2805 Female, age 91, both hemispheres 54.4
Nucleus gracilis
nTPM: 97.1
2627 Male, age 74, both hemispheres 237.3
2382 Male, age 80, both hemispheres 42.8
2299 Female, age 85, both hemispheres 11.2
Nucleus raphe magnus
nTPM: 373.4
2160 Male, age 61, both hemispheres 737.6
2172 Female, age 85, both hemispheres 490.8
2455 Male, age 74, both hemispheres 385.9
2328 Male, age 80, both hemispheres 243.8
2051 Male, age 76, both hemispheres 231.5
2459 Female, age 91, both hemispheres 150.7
Nucleus raphe obscurus
nTPM: 157.9
2800 Male, age 61, midline 221.9
2845 Female, age 85, midline 212.7
2142 Male, age 76, midline 39.0
Nucleus raphe pallidus
nTPM: 190.7
2183 Male, age 80, midline 286.2
1924 Male, age 61, midline 227.4
2145 Male, age 76, midline 58.7
Nucleus tractus solitarii
nTPM: 157.9
2144 Female, age 91, right hemisphere 359.7
2656 Male, age 76, both hemispheres 123.5
2191 Female, age 85, both hemispheres 94.5
2307 Male, age 80, both hemispheres 53.7
Paramedian reticular nucleus
nTPM: 279.0
2050 Female, age 85, both hemispheres 325.3
2057 Male, age 80, both hemispheres 320.2
2313 Male, age 61, both hemispheres 299.8
2052 Male, age 76, both hemispheres 170.6
Parvicellular reticular nuclei
nTPM: 236.3
2119 Male, age 80, both hemispheres 300.1
2095 Male, age 76, both hemispheres 224.8
2558 Male, age 74, both hemispheres 184.1
Parvicellular reticular nuclei, medullary
nTPM: 265.4
2189 Female, age 91, both hemispheres 332.3
2091 Female, age 85, both hemispheres 298.1
2181 Male, age 80, left hemisphere 165.9
Peritrigeminal nucleus
nTPM: 284.2
2179 Male, age 61, both hemispheres 355.3
2136 Male, age 76, both hemispheres 252.2
2067 Female, age 85, both hemispheres 245.1
Pontine nuclei
nTPM: 368.2
2727 Male, age 61, right hemisphere 687.5
1863 Male, age 55, unknown 579.6
2109 Female, age 72, unknown 446.2
2787 Female, age 85, both hemispheres 431.3
1968 Male, age 76, left hemisphere 339.5
2454 Male, age 74, left hemisphere 230.5
2319 Female, age 91, both hemispheres 122.2
2115 Male, age 80, left hemisphere 108.8
Pontine raphe nucleus
nTPM: 284.3
2122 Female, age 85, midline 349.0
2853 Male, age 76, midline 219.5
Posteroventral cochlear nucleus
nTPM: 139.1
2070 Male, age 76, both hemispheres 233.7
2752 Female, age 85, both hemispheres 223.9
2371 Male, age 61, both hemispheres 85.7
2341 Male, age 80, both hemispheres 80.8
2135 Female, age 91, both hemispheres 71.2
Prepositus hypoglossal nucleus
nTPM: 207.5
2855 Female, age 85, right hemisphere 277.2
2086 Male, age 80, both hemispheres 137.9
Principal sensory trigeminal nucleus
nTPM: 337.0
2158 Male, age 61, both hemispheres 592.4
2324 Male, age 76, both hemispheres 307.4
2008 Male, age 80, left hemisphere 294.9
2367 Female, age 91, left hemisphere 153.1
Reticular pontine nucleus, caudal
nTPM: 205.3
2332 Male, age 80, right hemisphere 276.7
2092 Male, age 76, both hemispheres 243.8
2559 Male, age 74, both hemispheres 161.5
2457 Female, age 91, both hemispheres 139.0
Reticular pontine nucleus, oral
nTPM: 215.7
2012 Female, age 85, both hemispheres 281.1
2361 Male, age 74, both hemispheres 266.4
1939 Male, age 80, both hemispheres 226.0
2167 Male, age 76, both hemispheres 172.4
2366 Female, age 91, both hemispheres 132.6
Reticulotegmental nucleus
nTPM: 221.2
2325 Male, age 76, both hemispheres 289.4
2452 Male, age 74, both hemispheres 237.8
2322 Female, age 91, both hemispheres 198.2
2333 Male, age 80, both hemispheres 159.5
Spinal trigeminal nucleus, caudal
nTPM: 252.0
2390 Female, age 91, both hemispheres 607.9
2447 Male, age 76, both hemispheres 272.0
2642 Male, age 74, both hemispheres 166.8
2308 Male, age 80, both hemispheres 122.0
2312 Male, age 61, both hemispheres 91.2
Spinal trigeminal nucleus, interpolar
nTPM: 392.1
2625 Male, age 61, both hemispheres 804.4
2066 Male, age 76, right hemisphere 552.4
2389 Female, age 91, both hemispheres 242.4
2033 Male, age 80, both hemispheres 217.8
2386 Female, age 85, both hemispheres 143.2
Spinal trigeminal nucleus, oral
nTPM: 225.0
2164 Male, age 80, both hemispheres 313.0
2737 Female, age 85, both hemispheres 238.6
1978 Male, age 76, both hemispheres 123.5
Spinal vestibular nucleus
nTPM: 207.3
2186 Female, age 91, both hemispheres 248.7
2748 Male, age 76, both hemispheres 227.4
2780 Male, age 80, both hemispheres 224.2
2384 Male, age 74, both hemispheres 197.1
2806 Female, age 85, both hemispheres 179.8
2796 Male, age 61, both hemispheres 166.5
Subcoeruleus area
nTPM: 199.7
2323 Female, age 91, left hemisphere 253.3
1958 Male, age 80, both hemispheres 249.2
2089 Male, age 76, left hemisphere 224.4
2451 Male, age 74, both hemispheres 151.4
2369 Female, age 85, left hemisphere 120.3
Superior olive
nTPM: 237.5
1875 Female, age 85, both hemispheres 376.7
2364 Male, age 74, right hemisphere 245.1
2020 Male, age 76, both hemispheres 218.6
2329 Male, age 80, right hemisphere 206.0
2561 Female, age 91, both hemispheres 141.0
Superior vestibular nucleus
nTPM: 167.2
2015 Male, age 80, both hemispheres 207.8
2383 Male, age 74, both hemispheres 152.5
2061 Male, age 76, both hemispheres 141.5
Ventral medullary reticular nucleus
nTPM: 159.8
2060 Male, age 76, both hemispheres 170.1
2372 Male, age 61, both hemispheres 149.6
Ventral periolivary nuclei
nTPM: 272.8
2130 Female, age 85, both hemispheres 395.8
2165 Male, age 80, both hemispheres 345.2
2023 Male, age 76, both hemispheres 194.7
2794 Female, age 91, left hemisphere 155.5
Ventrolateral medulla, A1-C1 cell groups
nTPM: 218.8
2741 Female, age 85, both hemispheres 310.5
1986 Male, age 76, both hemispheres 288.0
2180 Male, age 61, both hemispheres 213.4
2302 Female, age 91, both hemispheres 168.5
2118 Male, age 80, both hemispheres 113.4
Ventrolateral tegmental area, A5 NE cell group
nTPM: 216.4
2449 Male, age 74, both hemispheres 298.1
2840 Female, age 85, both hemispheres 273.0
1959 Male, age 76, both hemispheres 242.6
2359 Male, age 61, both hemispheres 202.9
2161 Male, age 80, both hemispheres 194.8
2456 Female, age 91, both hemispheres 87.0

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 2760.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1268.0
FF:10182-103D2 60 years, female 1710.2
FF:10165-103B3 76 years, female 825.9
Medulla oblongata
Scaled Tags Per Million: 843.6
FF:10038-101F2 18-64 years, mixed 1258.4
FF:10174-103C3 60 years, female 692.3
FF:10155-103A2 76 years, female 580.1
Pons
Scaled Tags Per Million: 2760.9
FF:10033-101E6 18-54 years, mixed 2760.9

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 425.9
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 356.9
Samples: 4

Max nTPM: 431.2
Min nTPM: 238.6
Sample A Female 431.2
Sample B Female 362.4
Sample C Male 395.5
Sample D Male 238.6
Pons
nTPM: 425.9
Samples: 4

Max nTPM: 528.5
Min nTPM: 342.2
Sample A Female 528.5
Sample B Female 342.2
Sample C Male 413.5
Sample D Male 419.3

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 80.9
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 80.9
Samples: 4

Max nTPM: 91.5
Min nTPM: 67.4
Sample A Male 91.5
Sample B Male 84.9
Sample C Female 67.4
Sample D Female 79.9

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 16.4
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 16.4
71570737 Antisense, RP_050505_01_H06, Mouse strain C57BL/6J (56 days, male) 17.4
73834355 Antisense, RP_051212_03_G08, Mouse strain C57BL/6J (56 days, male) 15.5
Pons
Expression energy: 16.3
71570737 Antisense, RP_050505_01_H06, Mouse strain C57BL/6J (56 days, male) 17.3
73834355 Antisense, RP_051212_03_G08, Mouse strain C57BL/6J (56 days, male) 15.4

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