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PPP1R1B
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  • PPP1R1B
BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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177.564
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:232.4 nTPM
HPA:232.4 nTPM
FANTOM5:105.7 Scaled Tags Per Million
Pig:21.3 nTPM
Allen mouse:3.5 Expression energy

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity .

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, antibody HPA048630
Pons mean intensity 177.564
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity .

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FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 50.478
Parabrachial nucleus 103.657
Principle sensory trigeminal nucleus 58.550
Locus coeruleus 170.822
Pontine nucleus 47.905
Vestibular nucleus 34.628
Pontine reticular nucleus, oral 21.043
Lateral lemniscus 33.172
Superior paraolivary nucleus 29.622

PONS - HPA Brain RNA-seq
Max nTPM 232.4
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 223.5
1984 Male, age 76, both hemispheres 245.6
2301 Female, age 85, both hemispheres 235.3
2090 Male, age 80, both hemispheres 212.4
2188 Female, age 91, both hemispheres 200.6
Dorsal cochlear nucleus
nTPM: 232.4
2802 Male, age 74, right hemisphere 244.0
2378 Male, age 80, both hemispheres 242.1
2370 Male, age 61, both hemispheres 233.9
2058 Male, age 76, both hemispheres 227.4
2187 Female, age 91, both hemispheres 214.9
Dorsal tegmental nucleus
nTPM: 203.8
1936 Male, age 76, left hemisphere 219.0
2083 Male, age 80, both hemispheres 205.8
2326 Male, age 74, both hemispheres 205.0
2358 Male, age 61, both hemispheres 185.2
Dorsolateral tegmental area
nTPM: 201.6
2141 Male, age 76, both hemispheres 211.5
2751 Female, age 85, both hemispheres 208.1
2654 Male, age 80, both hemispheres 205.1
2360 Male, age 74, both hemispheres 200.0
2337 Male, age 61, both hemispheres 183.2
Kolliker-Fuse nucleus
nTPM: 220.0
2315 Male, age 76, right hemisphere 260.0
2163 Male, age 80, both hemispheres 200.4
2793 Female, age 91, left hemisphere 199.7
Lateral lemniscal nuclei
nTPM: 196.6
2169 Male, age 76, both hemispheres 209.4
2746 Female, age 85, left hemisphere 202.0
2453 Male, age 74, right hemisphere 191.2
2320 Female, age 91, left hemisphere 191.1
2036 Male, age 80, both hemispheres 189.2
Lateral parabrachial nucleus
nTPM: 214.4
2792 Male, age 76, both hemispheres 235.9
2139 Female, age 85, right hemisphere 228.2
2013 Male, age 80, both hemispheres 211.7
2790 Male, age 61, both hemispheres 181.6
Lateral vestibular nucleus
nTPM: 221.8
2311 Male, age 80, both hemispheres 226.6
2184 Male, age 76, both hemispheres 217.1
Locus coeruleus
nTPM: 206.0
2123 Female, age 91, both hemispheres 212.4
2317 Female, age 72, unknown 210.3
2162 Male, age 80, both hemispheres 208.5
1980 Male, age 76, both hemispheres 206.3
2788 Male, age 74, unknown 203.2
2720 Male, age 74, both hemispheres 202.2
2014 Male, age 55, unknown 199.1
Medial olivary nucleus
nTPM: 223.8
2138 Female, age 91, both hemispheres 253.4
1943 Male, age 61, both hemispheres 232.2
2851 Male, age 80, both hemispheres 214.1
1962 Male, age 76, both hemispheres 195.4
Medial parabrachial nucleus
nTPM: 206.5
2463 Female, age 85, right hemisphere 223.6
2786 Male, age 76, both hemispheres 210.1
2170 Female, age 91, both hemispheres 209.0
2854 Male, age 80, both hemispheres 202.3
2156 Male, age 61, both hemispheres 187.8
Medial periolivary nuclei
nTPM: 198.4
2063 Male, age 76, both hemispheres 202.3
2791 Male, age 74, right hemisphere 198.8
2458 Female, age 91, both hemispheres 197.9
2171 Female, age 85, both hemispheres 197.0
2081 Male, age 80, both hemispheres 195.9
Motor facial nucleus
nTPM: 202.7
2795 Female, age 91, both hemispheres 220.4
2062 Male, age 76, both hemispheres 211.1
2126 Male, age 61, both hemispheres 202.1
2697 Female, age 85, both hemispheres 199.2
2365 Male, age 74, right hemisphere 193.2
2327 Male, age 80, both hemispheres 190.3
Motor trigeminal nucleus
nTPM: 197.4
2309 Male, age 76, both hemispheres 209.9
2321 Female, age 91, both hemispheres 196.0
2560 Male, age 74, both hemispheres 195.7
2335 Male, age 61, both hemispheres 194.7
2079 Male, age 80, both hemispheres 190.8
Nuclei of the trapezoid body
nTPM: 200.9
1983 Male, age 76, both hemispheres 209.4
2368 Female, age 91, both hemispheres 206.2
2159 Male, age 61, both hemispheres 198.2
2166 Male, age 80, both hemispheres 197.2
2735 Female, age 85, both hemispheres 193.6
Paramedian reticular nucleus
nTPM: 191.6
2050 Female, age 85, both hemispheres 192.8
2313 Male, age 61, both hemispheres 192.0
2057 Male, age 80, both hemispheres 191.9
2052 Male, age 76, both hemispheres 189.5
Pontine nuclei
nTPM: 193.3
1968 Male, age 76, left hemisphere 205.2
2115 Male, age 80, left hemisphere 201.3
1863 Male, age 55, unknown 197.8
2319 Female, age 91, both hemispheres 192.7
2109 Female, age 72, unknown 189.9
2787 Female, age 85, both hemispheres 189.8
2727 Male, age 61, right hemisphere 188.2
2454 Male, age 74, left hemisphere 181.7
Pontine raphe nucleus
nTPM: 204.3
2853 Male, age 76, midline 214.9
2122 Female, age 85, midline 193.8
Posteroventral cochlear nucleus
nTPM: 209.5
2371 Male, age 61, both hemispheres 233.3
2752 Female, age 85, both hemispheres 209.4
2341 Male, age 80, both hemispheres 205.4
2135 Female, age 91, both hemispheres 201.6
2070 Male, age 76, both hemispheres 197.7
Principal sensory trigeminal nucleus
nTPM: 204.7
2324 Male, age 76, both hemispheres 234.5
2158 Male, age 61, both hemispheres 200.9
2367 Female, age 91, left hemisphere 192.9
2008 Male, age 80, left hemisphere 190.5
Reticular pontine nucleus, caudal
nTPM: 195.2
2092 Male, age 76, both hemispheres 207.0
2457 Female, age 91, both hemispheres 194.9
2332 Male, age 80, right hemisphere 190.7
2559 Male, age 74, both hemispheres 188.2
Reticular pontine nucleus, oral
nTPM: 199.1
2167 Male, age 76, both hemispheres 218.2
1939 Male, age 80, both hemispheres 203.2
2012 Female, age 85, both hemispheres 198.6
2366 Female, age 91, both hemispheres 196.2
2361 Male, age 74, both hemispheres 179.4
Reticulotegmental nucleus
nTPM: 207.4
2322 Female, age 91, both hemispheres 215.8
2325 Male, age 76, both hemispheres 210.5
2333 Male, age 80, both hemispheres 205.3
2452 Male, age 74, both hemispheres 198.2
Spinal trigeminal nucleus, oral
nTPM: 209.8
1978 Male, age 76, both hemispheres 215.5
2737 Female, age 85, both hemispheres 213.3
2164 Male, age 80, both hemispheres 200.5
Subcoeruleus area
nTPM: 204.2
2089 Male, age 76, left hemisphere 205.4
2369 Female, age 85, left hemisphere 205.1
2323 Female, age 91, left hemisphere 204.3
2451 Male, age 74, both hemispheres 204.3
1958 Male, age 80, both hemispheres 202.0
Superior olive
nTPM: 198.3
2020 Male, age 76, both hemispheres 204.5
2561 Female, age 91, both hemispheres 199.0
2364 Male, age 74, right hemisphere 197.7
2329 Male, age 80, right hemisphere 197.1
1875 Female, age 85, both hemispheres 193.5
Superior vestibular nucleus
nTPM: 224.6
2061 Male, age 76, both hemispheres 249.2
2383 Male, age 74, both hemispheres 214.3
2015 Male, age 80, both hemispheres 210.3
Ventral periolivary nuclei
nTPM: 198.1
2130 Female, age 85, both hemispheres 202.0
2165 Male, age 80, both hemispheres 199.8
2023 Male, age 76, both hemispheres 196.0
2794 Female, age 91, left hemisphere 194.6
Ventrolateral tegmental area, A5 NE cell group
nTPM: 199.6
1959 Male, age 76, both hemispheres 203.7
2840 Female, age 85, both hemispheres 203.5
2456 Female, age 91, both hemispheres 202.9
2161 Male, age 80, both hemispheres 201.1
2359 Male, age 61, both hemispheres 193.1
2449 Male, age 74, both hemispheres 193.1

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 105.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 105.7
FF:10182-103D2 60 years, female 120.3
FF:10165-103B3 76 years, female 91.1
Pons
Scaled Tags Per Million: 55.5
FF:10033-101E6 18-54 years, mixed 55.5

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 21.3
Pig sample Sample description nTPM
Pons
nTPM: 21.3
Samples: 4

Max nTPM: 28.0
Min nTPM: 9.3
Sample A Female 27.1
Sample B Female 9.3
Sample C Male 20.6
Sample D Male 28.0

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 3.5
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 3.5
576432 Antisense, RP_040826_01_H06, Mouse strain C57BL/6J (56 days, male) 6.0
73732146 Antisense, RP_051121_04_A04, Mouse strain C57BL/6J (56 days, male) 1.1

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.