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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:256.8 nTPM
HPA:256.8 nTPM
GTEx:302.7 nTPM
FANTOM5:483.4 Scaled Tags Per Million
Pig:223.9 nTPM
Mouse:304.9 nTPM
Allen mouse:10.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 256.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 247.9
2586 Male, age 75, left hemisphere 316.0
2666 Male, age 74, left hemisphere 282.7
2828 Female, age 72, unknown 258.6
1827 Male, age 72, unknown 254.8
1833 Male, age 53, unknown 243.5
1870 Female, age 42, unknown 242.7
1830 Male, age 51, unknown 231.5
2411 Female, age 72, unknown 225.0
2219 Male, age 76, both hemispheres 220.1
2019 Male, age 18, unknown 204.6
Dorsal raphe nucleus
nTPM: 229.4
1828 Male, age 53, unknown 244.3
2047 Male, age 72, unknown 244.3
2750 Male, age 76, both hemispheres 232.5
2298 Female, age 72, unknown 221.4
2016 Female, age 72, unknown 204.4
Inferior colliculus
nTPM: 223.6
2849 Male, age 72, unknown 265.2
1848 Female, age 42, unknown 232.2
1890 Male, age 53, unknown 201.6
2097 Female, age 72, unknown 195.5
Median raphe nucleus
nTPM: 256.8
2220 Male, age 76, midline 256.8
Pedunculopontine tegmental nucleus
nTPM: 233.8
2334 Male, age 80, both hemispheres 259.5
1921 Female, age 85, both hemispheres 223.7
2338 Male, age 61, both hemispheres 218.0
Periaquaductal grey, anterior
nTPM: 248.5
1947 Male, age 18, unknown 262.0
2502 Female, age 75, unknown 243.5
1795 Male, age 51, unknown 240.0
Periaquaductal grey, dorsal
nTPM: 219.6
2850 Male, age 76, both hemispheres 246.2
2464 Female, age 72, unknown 215.4
1840 Male, age 53, unknown 214.8
1831 Male, age 72, unknown 201.9
Periaquaductal grey, lateral
nTPM: 206.6
2053 Male, age 18, unknown 218.4
2140 Male, age 76, both hemispheres 210.8
2272 Male, age 74, both hemispheres 190.8
Pretectal area
nTPM: 228.1
1817 Female, age 42, unknown 255.2
2825 Male, age 18, unknown 251.5
1816 Male, age 51, unknown 248.8
2667 Female, age 75, unknown 248.4
1815 Male, age 53, unknown 238.3
2007 Male, age 72, unknown 227.3
1944 Female, age 72, unknown 226.9
2407 Male, age 75, both hemispheres 220.8
2224 Female, age 72, unknown 210.4
2316 Male, age 76, right hemisphere 200.8
2273 Male, age 74, both hemispheres 180.2
Red nucleus
nTPM: 238.8
1821 Female, age 72, unknown 271.9
2584 Male, age 75, left hemisphere 256.2
2769 Male, age 72, unknown 248.9
2227 Male, age 72, unknown 240.7
1954 Female, age 42, unknown 239.2
2823 Male, age 76, right hemisphere 237.1
1865 Male, age 51, unknown 235.8
2725 Female, age 75, unknown 235.0
2588 Male, age 74, left hemisphere 234.7
1904 Male, age 53, unknown 227.3
2503 Female, age 72, unknown 222.9
2785 Male, age 18, unknown 216.2
Substantia nigra
nTPM: 255.8
1916 Female, age 42, unknown 296.5
1941 Male, age 53, unknown 290.8
2699 Male, age 18, unknown 286.1
1851 Male, age 51, unknown 265.4
2665 Male, age 74, both hemispheres 257.8
2583 Male, age 75, right hemisphere 254.7
1889 Female, age 72, unknown 250.8
2241 Male, age 72, unknown 227.8
2590 Female, age 75, unknown 218.5
2409 Female, age 72, unknown 209.6
Superior colliculus
nTPM: 232.0
2664 Male, age 75, both hemispheres 281.9
2668 Female, age 75, unknown 252.3
1796 Male, age 53, unknown 245.0
1839 Male, age 51, unknown 238.8
1895 Male, age 76, right hemisphere 223.5
2587 Male, age 74, left hemisphere 222.9
2261 Male, age 18, unknown 220.1
2087 Female, age 72, unknown 219.8
1913 Female, age 42, unknown 215.9
1995 Male, age 72, unknown 199.9
Ventral tegmental area
nTPM: 236.2
1915 Female, age 42, unknown 258.4
2410 Female, age 72, unknown 249.1
2223 Female, age 72, unknown 246.4
2218 Male, age 76, both hemispheres 238.2
1942 Male, age 51, unknown 219.3
2021 Male, age 53, unknown 205.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 302.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 302.7
Samples: 139

Max nTPM: 600.3
Min nTPM: 155.9
Std nTPM: 67.1
Median nTPM: 294.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 600.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 478.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 441.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 439.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 437.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 432.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 427.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 425.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 424.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 412.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 410.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 408.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 403.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 398.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 387.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 385.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 378.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 368.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 364.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 364.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 364.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 363.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 361.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 358.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 356.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 353.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 352.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 351.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 351.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 351.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 351.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 348.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 347.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 347.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 346.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 346.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 343.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 342.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 342.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 338.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 338.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 337.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 331.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 331.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 327.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 324.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 324.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 320.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 315.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 313.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 310.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 309.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 306.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 306.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 303.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 303.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 302.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 302.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 300.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 299.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 299.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 298.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 298.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 297.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 296.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 295.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 294.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 294.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 294.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 294.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 294.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 293.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 289.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 288.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 287.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 287.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 287.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 287.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 285.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 285.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 284.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 284.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 284.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 283.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 283.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 282.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 282.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 281.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 278.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 278.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 276.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 276.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 272.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 272.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 271.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 271.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 270.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 270.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 270.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 268.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 267.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 266.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 264.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 263.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 261.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 261.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 255.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 255.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 252.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 252.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 251.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 251.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 250.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 249.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 249.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 248.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 245.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 244.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 237.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 229.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 227.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 219.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 218.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 216.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 215.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 215.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 214.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 211.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 211.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 211.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 207.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 205.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 204.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 204.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 202.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 201.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 189.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 180.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 155.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 483.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 483.4
FF:10158-103A5 76 years, female 483.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 223.9
Pig sample Sample description nTPM
Midbrain
nTPM: 223.9
Samples: 4

Max nTPM: 299.8
Min nTPM: 192.0
Sample A Female 299.8
Sample B Female 192.2
Sample C Male 211.7
Sample D Male 192.0
Periaqueductal gray
nTPM: 170.5
Samples: 3

Max nTPM: 180.3
Min nTPM: 163.7
Sample B Female 167.4
Sample C Male 180.3
Sample D Male 163.7
Substantia nigra
nTPM: 213.3
Samples: 4

Max nTPM: 250.0
Min nTPM: 160.2
Sample A Female 250.0
Sample B Female 160.2
Sample C Male 246.3
Sample D Male 196.8
Superior colliculi
nTPM: 215.4
Samples: 4

Max nTPM: 239.9
Min nTPM: 157.0
Sample A Female 232.3
Sample B Female 157.0
Sample C Male 239.9
Sample D Male 232.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 304.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 304.9
Samples: 4

Max nTPM: 322.2
Min nTPM: 297.3
Sample A Male 322.2
Sample B Male 297.3
Sample C Female 299.5
Sample D Female 300.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.8
69013750 Antisense, RP_050309_02_H09, Mouse strain C57BL/6J (56 days, male) 10.8

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