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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:97.8 nTPM
HPA:97.8 nTPM
GTEx:118.4 nTPM
FANTOM5:64.0 Scaled Tags Per Million
Pig:11.6 nTPM
Mouse:118.8 nTPM
Allen mouse:0.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 97.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 92.5
2586 Male, age 75, left hemisphere 96.9
1870 Female, age 42, unknown 95.3
2828 Female, age 72, unknown 95.1
1833 Male, age 53, unknown 93.4
1827 Male, age 72, unknown 92.0
1830 Male, age 51, unknown 91.5
2411 Female, age 72, unknown 91.1
2219 Male, age 76, both hemispheres 90.8
2019 Male, age 18, unknown 90.7
2666 Male, age 74, left hemisphere 87.8
Dorsal raphe nucleus
nTPM: 96.1
2016 Female, age 72, unknown 99.7
2298 Female, age 72, unknown 96.4
1828 Male, age 53, unknown 95.7
2047 Male, age 72, unknown 94.5
2750 Male, age 76, both hemispheres 94.2
Inferior colliculus
nTPM: 97.8
1848 Female, age 42, unknown 100.4
2097 Female, age 72, unknown 98.0
1890 Male, age 53, unknown 97.5
2849 Male, age 72, unknown 95.6
Median raphe nucleus
nTPM: 95.9
2220 Male, age 76, midline 95.9
Pedunculopontine tegmental nucleus
nTPM: 93.0
1921 Female, age 85, both hemispheres 97.5
2334 Male, age 80, both hemispheres 94.6
2338 Male, age 61, both hemispheres 87.0
Periaquaductal grey, anterior
nTPM: 94.4
2502 Female, age 75, unknown 96.8
1947 Male, age 18, unknown 95.5
1795 Male, age 51, unknown 90.8
Periaquaductal grey, dorsal
nTPM: 96.3
2850 Male, age 76, both hemispheres 100.1
1840 Male, age 53, unknown 99.5
2464 Female, age 72, unknown 96.1
1831 Male, age 72, unknown 89.7
Periaquaductal grey, lateral
nTPM: 94.3
2140 Male, age 76, both hemispheres 99.4
2053 Male, age 18, unknown 93.9
2272 Male, age 74, both hemispheres 89.7
Pretectal area
nTPM: 94.7
2667 Female, age 75, unknown 98.3
1817 Female, age 42, unknown 97.4
1944 Female, age 72, unknown 97.0
2224 Female, age 72, unknown 96.5
2316 Male, age 76, right hemisphere 96.0
1815 Male, age 53, unknown 93.6
1816 Male, age 51, unknown 93.5
2825 Male, age 18, unknown 93.5
2273 Male, age 74, both hemispheres 92.4
2007 Male, age 72, unknown 92.0
2407 Male, age 75, both hemispheres 91.3
Red nucleus
nTPM: 94.8
1821 Female, age 72, unknown 101.8
1954 Female, age 42, unknown 100.0
2227 Male, age 72, unknown 98.7
1904 Male, age 53, unknown 97.3
2769 Male, age 72, unknown 97.0
2503 Female, age 72, unknown 96.4
2823 Male, age 76, right hemisphere 96.4
1865 Male, age 51, unknown 95.0
2785 Male, age 18, unknown 91.2
2725 Female, age 75, unknown 89.0
2588 Male, age 74, left hemisphere 88.3
2584 Male, age 75, left hemisphere 86.7
Substantia nigra
nTPM: 97.1
2241 Male, age 72, unknown 106.9
2699 Male, age 18, unknown 104.2
1916 Female, age 42, unknown 99.6
1851 Male, age 51, unknown 99.3
1889 Female, age 72, unknown 97.9
2409 Female, age 72, unknown 94.8
2590 Female, age 75, unknown 93.1
2665 Male, age 74, both hemispheres 93.1
1941 Male, age 53, unknown 91.8
2583 Male, age 75, right hemisphere 90.5
Superior colliculus
nTPM: 93.1
2668 Female, age 75, unknown 96.7
1895 Male, age 76, right hemisphere 95.7
2087 Female, age 72, unknown 95.1
1839 Male, age 51, unknown 93.9
2664 Male, age 75, both hemispheres 92.7
2261 Male, age 18, unknown 92.3
1995 Male, age 72, unknown 92.0
1796 Male, age 53, unknown 91.7
2587 Male, age 74, left hemisphere 90.8
1913 Female, age 42, unknown 90.5
Ventral tegmental area
nTPM: 93.2
1942 Male, age 51, unknown 94.9
1915 Female, age 42, unknown 94.2
2218 Male, age 76, both hemispheres 94.0
2021 Male, age 53, unknown 93.7
2410 Female, age 72, unknown 91.9
2223 Female, age 72, unknown 90.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 118.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 118.4
Samples: 139

Max nTPM: 494.2
Min nTPM: 23.6
Std nTPM: 74.2
Median nTPM: 102.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 494.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 434.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 398.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 332.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 283.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 266.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 261.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 248.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 239.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 233.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 228.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 210.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 202.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 200.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 199.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 196.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 187.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 186.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 177.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 174.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 171.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 168.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 161.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 159.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 158.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 156.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 155.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 153.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 152.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 149.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 149.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 148.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 147.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 145.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 143.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 142.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 141.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 139.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 137.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 136.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 135.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 134.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 133.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 133.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 131.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 131.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 128.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 124.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 123.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 121.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 121.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 117.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 115.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 114.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 113.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 112.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 110.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 109.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 107.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 107.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 106.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 106.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 105.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 104.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 104.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 103.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 103.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 102.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 102.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 101.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 101.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 101.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 100.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 97.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 95.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 95.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 95.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 93.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 93.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 92.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 92.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 92.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 91.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 91.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 89.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 89.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 89.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 88.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 86.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 85.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 84.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 83.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 82.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 82.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 81.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 80.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 80.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 78.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 77.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 77.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 76.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 76.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 73.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 72.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 71.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 69.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 68.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 67.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 67.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 65.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 64.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 60.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 59.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 58.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 56.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 56.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 55.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 55.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 54.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 53.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 53.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 51.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 49.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 48.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 43.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 42.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 42.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 42.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 41.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 40.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 37.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 37.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 36.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 33.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 32.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 31.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 23.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 64.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 64.0
FF:10158-103A5 76 years, female 64.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 11.6
Pig sample Sample description nTPM
Midbrain
nTPM: 11.7
Samples: 4

Max nTPM: 14.3
Min nTPM: 10.1
Sample A Female 14.3
Sample B Female 12.0
Sample C Male 10.1
Sample D Male 10.2
Periaqueductal gray
nTPM: 9.8
Samples: 3

Max nTPM: 10.1
Min nTPM: 9.4
Sample B Female 10.1
Sample C Male 9.4
Sample D Male 10.0
Substantia nigra
nTPM: 10.3
Samples: 4

Max nTPM: 11.8
Min nTPM: 8.9
Sample A Female 11.8
Sample B Female 8.9
Sample C Male 10.0
Sample D Male 10.6
Superior colliculi
nTPM: 10.9
Samples: 4

Max nTPM: 11.8
Min nTPM: 9.2
Sample A Female 11.8
Sample B Female 9.2
Sample C Male 11.3
Sample D Male 11.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 118.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 118.8
Samples: 4

Max nTPM: 125.9
Min nTPM: 113.8
Sample A Male 125.9
Sample B Male 113.8
Sample C Female 116.6
Sample D Female 118.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.5
76003665 Antisense, RP_060608_03_A06, Mouse strain C57BL/6J (56 days, male) 0.5

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