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TISSUE PRIMARY DATA KIDNEY Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN NASOPHARYNX ORAL MUCOSA
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
ANTIBODIES
AND
VALIDATION
Dictionary
Kidney
Tissue proteome
Kidney
KIDNEY - Expression summary
Protein expression
Kidneyi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
h
m
l
n
Bowman's capsule: Not detected
Cells in glomeruli: Not detected
Collecting ducts: Not detected
Distal tubules: Low
Proximal tubules (cell body): High
Proximal tubules (microvilli): Not detected
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Cytoplasmic staining in proximal tubules.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:333.1 nTPM
HPA:333.1 nTPM
GTEx:142.4 nTPM
FANTOM5:451.5 Scaled Tags Per Million

KIDNEY - Multiplex stainingi

Antibody localization in the annotated cell types/states of the current human tissue is reported as main/additional locations, percent overlap between the antibody and cell type/state-specific markers, and subcellular location. The scores are based on multiplex immunohistochemistry profiling in selected tissues.

Main locations are characterized by a high overlap between the antibody and the cell type/state-specific marker combined with strong antibody signal intensity, while additional locations are characterized by lower overlap and weaker antibody signal intensity.

The antibody of interest is reported in green, while cell types/states are reported in various other colors, and DAPI (marks nucleus) is reported in blue. Colors can be toggled on and off by clicking on the name of the cell type/state of interest, “Antibody” or “DAPI”. To toggle between the different tissue samples, click on the miniature images at the right bottom corner of the main image. The miniature images appear upon hovering the mouse over that area.

Read more
- Antibody HPA044573
Main location Proximal tubules
No antibody overlap
Antibody overlap>75%
LocationCytoplasm
No antibody overlap
No antibody overlap
No antibody overlap

KIDNEY - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Read more
Antibody HPA044573
Bowman's capsule Not detected
Cells in glomeruli Not detected
Collecting ducts Not detected
Distal tubules Low
Proximal tubules (cell body) High
Proximal tubules (microvilli) Not detected



KIDNEY - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Read more
Average nTPM 333.1
overview
Female, age 58
Kidney sample 55
nTPM: 398.1
Cell types%
Cells in tubules:
60

Cells in glomeruli:
20

Fibroblasts:
5

Other cell types:
15

overview
Female, age 67
Kidney sample 56
nTPM: 362.1
Cell types%
Cells in tubules:
70

Cells in glomeruli:
15

Fibroblasts:
10

Other cell types:
5

overview
Female, age 55
Kidney sample 57
nTPM: 140.7
Cell types%
Cells in tubules:
80

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
5

overview
Male, age 46
Kidney sample 58
nTPM: 424.5
Cell types%
Cells in tubules:
60

Cells in glomeruli:
25

Fibroblasts:
5

Other cell types:
10

overview
Female, age 57
Kidney sample 358
nTPM: 262.9
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Male, age 78
Kidney sample 377
nTPM: 268.7
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
20

overview
Male, age 73
Kidney sample 380
nTPM: 587.8
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Female, age 59
Kidney sample 394
nTPM: 297.4
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
15

overview
Female, age 48
Kidney sample 414
nTPM: 255.7
Cell types%
Cells in tubules:
60

Cells in glomeruli:
5

Fibroblasts:
10

Other cell types:
25


KIDNEY - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 142.4
GTEx sample id Sample description nTPM
Kidney - Cortex
Average nTPM: 142.4
Samples: 85

Max nTPM: 528.9
Min nTPM: 15.6
Std nTPM: 101.4
Median nTPM: 113.0
GTEX-13NYB-1726-SM-5N9G2 40-49 years, male 528.9
GTEX-T6MN-1826-SM-EXOHN 50-59 years, male 520.2
GTEX-1JMQJ-1726-SM-E9U4V 50-59 years, male 387.7
GTEX-14E6D-2526-SM-5YYA9 50-59 years, male 386.5
GTEX-1KWVE-0826-SM-CXZKO 30-39 years, male 348.9
GTEX-REY6-1826-SM-EAZAT 60-69 years, male 306.7
GTEX-1NV8Z-2226-SM-EXOJ2 60-69 years, male 272.9
GTEX-14C5O-2026-SM-5YYB1 60-69 years, male 263.4
GTEX-17HHY-2326-SM-7KFSR 50-59 years, male 262.7
GTEX-11OF3-1326-SM-5N9FJ 60-69 years, male 255.8
GTEX-1H3NZ-2126-SM-9WPQ6 60-69 years, male 232.0
GTEX-QDT8-1726-SM-EYYV6 30-39 years, female 225.7
GTEX-13OW6-1826-SM-5N9F9 50-59 years, male 223.2
GTEX-16MT8-1926-SM-7EPGL 60-69 years, female 218.4
GTEX-1JMPZ-1226-SM-ARU8Y 30-39 years, male 216.3
GTEX-1GF9V-1926-SM-9JGHE 60-69 years, male 215.1
GTEX-1GMR3-2426-SM-7MXV2 40-49 years, male 210.7
GTEX-1GF9W-1326-SM-7P8PX 60-69 years, male 205.7
GTEX-1IKK5-0926-SM-A9G2U 60-69 years, male 202.4
GTEX-15DYW-2026-SM-6AJBD 60-69 years, female 201.1
GTEX-S33H-1426-SM-EZ6L7 30-39 years, male 191.8
GTEX-Y5V6-2026-SM-5IFHO 60-69 years, male 187.9
GTEX-1497J-0826-SM-5NQAJ 60-69 years, male 183.1
GTEX-1BAJH-1826-SM-731DA 70-79 years, male 181.9
GTEX-QDVN-1626-SM-48TZC 50-59 years, male 180.8
GTEX-1HBPI-2026-SM-CE6RZ 50-59 years, male 179.5
GTEX-O5YV-1226-SM-EV795 60-69 years, female 178.0
GTEX-1R9PO-1626-SM-E6CPT 60-69 years, female 175.1
GTEX-T5JC-1526-SM-4DM68 20-29 years, male 174.1
GTEX-P4QS-1126-SM-3NMD5 60-69 years, male 170.1
GTEX-Y5V5-1226-SM-EYYVP 60-69 years, female 167.9
GTEX-1K9T9-1826-SM-CXZK2 50-59 years, female 158.8
GTEX-XPVG-0526-SM-4B65N 50-59 years, male 141.1
GTEX-15CHQ-2126-SM-6871M 60-69 years, male 139.8
GTEX-1JJ6O-2526-SM-AHZ3J 60-69 years, male 137.0
GTEX-1JMQK-1926-SM-CJI3B 60-69 years, male 128.1
GTEX-1HB9E-1826-SM-D4P33 50-59 years, male 127.9
GTEX-ZC5H-1726-SM-5HL7X 40-49 years, female 125.8
GTEX-12WSG-0826-SM-5EQ5A 50-59 years, female 123.7
GTEX-ZDXO-0226-SM-4WKH7 60-69 years, male 123.6
GTEX-17F96-1926-SM-7MGWY 70-79 years, male 119.1
GTEX-1E2YA-1626-SM-7MGXS 50-59 years, male 118.0
GTEX-1A8FM-2026-SM-7P8RN 50-59 years, female 113.0
GTEX-14C39-2126-SM-664OH 40-49 years, male 112.5
GTEX-1JMLX-1526-SM-AHZ3N 50-59 years, male 111.3
GTEX-1EKGG-2226-SM-7IGOA 60-69 years, male 108.7
GTEX-1QP6S-1526-SM-EXUSG 40-49 years, male 106.7
GTEX-145MN-0326-SM-5QGQI 30-39 years, male 104.3
GTEX-1IL2V-1826-SM-ARU7R 70-79 years, male 104.2
GTEX-1I1GP-1926-SM-CNNQU 50-59 years, male 103.6
GTEX-1F48J-2226-SM-7MXTN 50-59 years, female 102.2
GTEX-1H3VY-1926-SM-9JGHJ 50-59 years, male 100.7
GTEX-1N2EF-1426-SM-EXUSH 60-69 years, male 100.1
GTEX-1HCU7-1826-SM-A9G2A 50-59 years, male 98.2
GTEX-1PWST-2226-SM-EVR3G 70-79 years, male 93.2
GTEX-1AX8Z-2326-SM-731CR 60-69 years, male 92.0
GTEX-13OVL-1826-SM-5KLZR 50-59 years, male 90.7
GTEX-1C6VQ-2326-SM-7IGN1 50-59 years, male 89.9
GTEX-1GTWX-1826-SM-9QEHG 60-69 years, male 89.9
GTEX-ZYFG-1626-SM-5GZYY 60-69 years, female 85.1
GTEX-QLQW-1626-SM-CMKFE 30-39 years, male 83.5
GTEX-1J1OQ-1426-SM-AHZ3P 40-49 years, female 71.9
GTEX-11GS4-2326-SM-5A5KS 60-69 years, male 68.9
GTEX-RN64-1626-SM-48FD7 50-59 years, male 67.0
GTEX-13O1R-2526-SM-5N9FW 60-69 years, male 65.5
GTEX-1OJC4-2326-SM-DTXA5 50-59 years, female 62.7
GTEX-1CB4J-1926-SM-7MGX8 60-69 years, male 60.4
GTEX-1GN1U-2126-SM-AHZ4J 50-59 years, female 56.9
GTEX-1LG7Y-2726-SM-D5OVW 50-59 years, male 56.1
GTEX-ZYT6-2226-SM-5GIC9 30-39 years, male 55.6
GTEX-1MUQO-2526-SM-E9TJN 60-69 years, male 51.2
GTEX-13RTJ-2226-SM-5S2Q1 60-69 years, male 48.0
GTEX-ZVZP-0926-SM-5GIDB 50-59 years, male 46.9
GTEX-ZLFU-0926-SM-5P9F8 40-49 years, male 46.8
GTEX-NPJ8-2226-SM-3TW8D 40-49 years, male 45.2
GTEX-13112-2126-SM-5GCO4 50-59 years, male 42.4
GTEX-13OVI-1126-SM-5KLZF 60-69 years, female 42.1
GTEX-147F4-2626-SM-5Q5CS 50-59 years, male 35.6
GTEX-1A3MW-2226-SM-73KUX 60-69 years, female 34.0
GTEX-1399S-0526-SM-5IJG8 30-39 years, female 31.8
GTEX-ZE9C-1426-SM-4WKGM 60-69 years, male 31.2
GTEX-17F97-1926-SM-7IGM4 50-59 years, male 29.7
GTEX-12696-0926-SM-5FQTV 60-69 years, male 28.6
GTEX-1N2DW-1826-SM-EAZ54 50-59 years, male 21.0
GTEX-11TTK-1926-SM-5PNW8 60-69 years, female 15.6
Show allShow less
Kidney - Medulla
Average nTPM: 78.9
Samples: 4

Max nTPM: 139.2
Min nTPM: 30.3
Std nTPM: 40.4
Median nTPM: 73.0
GTEX-RU72-1926-SM-EAZ3F 50-59 years, female 139.2
GTEX-TKQ2-0626-SM-EZ6LB 50-59 years, male 88.5
GTEX-R55E-2026-SM-EZ6L1 20-29 years, male 57.5
GTEX-T5JC-1626-SM-EZ6KW 20-29 years, male 30.3

KIDNEY - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 451.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Kidney
Scaled Tags Per Million: 451.5
FF:10017-101C8 60,62,63 years, female 451.5

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