We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
TPT1
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • TPT1
BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:2185.5 nTPM
HPA:2185.5 nTPM
FANTOM5:938.4 Scaled Tags Per Million
Pig:889.1 nTPM
Allen mouse:10.6 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 2185.5
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 2048.7
2090 Male, age 80, both hemispheres 2118.8
2188 Female, age 91, both hemispheres 2111.5
2301 Female, age 85, both hemispheres 2079.2
1984 Male, age 76, both hemispheres 1885.1
Dorsal cochlear nucleus
nTPM: 2025.5
2378 Male, age 80, both hemispheres 2111.5
2187 Female, age 91, both hemispheres 2080.9
2802 Male, age 74, right hemisphere 2039.9
2370 Male, age 61, both hemispheres 1990.3
2058 Male, age 76, both hemispheres 1904.9
Dorsal tegmental nucleus
nTPM: 2013.0
2326 Male, age 74, both hemispheres 2093.1
2358 Male, age 61, both hemispheres 2006.9
2083 Male, age 80, both hemispheres 1977.3
1936 Male, age 76, left hemisphere 1974.7
Dorsolateral tegmental area
nTPM: 2006.0
2337 Male, age 61, both hemispheres 2091.2
2654 Male, age 80, both hemispheres 2073.5
2751 Female, age 85, both hemispheres 1995.6
2360 Male, age 74, both hemispheres 1993.4
2141 Male, age 76, both hemispheres 1876.4
Kolliker-Fuse nucleus
nTPM: 2044.1
2315 Male, age 76, right hemisphere 2127.1
2793 Female, age 91, left hemisphere 2049.3
2163 Male, age 80, both hemispheres 1955.8
Lateral lemniscal nuclei
nTPM: 1917.1
2746 Female, age 85, left hemisphere 1964.8
2320 Female, age 91, left hemisphere 1931.4
2036 Male, age 80, both hemispheres 1908.1
2169 Male, age 76, both hemispheres 1900.6
2453 Male, age 74, right hemisphere 1880.7
Lateral parabrachial nucleus
nTPM: 2059.2
2792 Male, age 76, both hemispheres 2175.4
2013 Male, age 80, both hemispheres 2120.2
2139 Female, age 85, right hemisphere 1994.0
2790 Male, age 61, both hemispheres 1947.1
Lateral vestibular nucleus
nTPM: 2013.2
2311 Male, age 80, both hemispheres 2116.8
2184 Male, age 76, both hemispheres 1909.5
Locus coeruleus
nTPM: 1954.0
2720 Male, age 74, both hemispheres 2051.7
2788 Male, age 74, unknown 1971.6
2123 Female, age 91, both hemispheres 1970.8
2162 Male, age 80, both hemispheres 1947.2
2317 Female, age 72, unknown 1919.4
2014 Male, age 55, unknown 1917.9
1980 Male, age 76, both hemispheres 1899.4
Medial olivary nucleus
nTPM: 2185.5
1943 Male, age 61, both hemispheres 2253.9
2851 Male, age 80, both hemispheres 2237.4
1962 Male, age 76, both hemispheres 2191.5
2138 Female, age 91, both hemispheres 2059.0
Medial parabrachial nucleus
nTPM: 1999.5
2854 Male, age 80, both hemispheres 2109.1
2170 Female, age 91, both hemispheres 2092.6
2786 Male, age 76, both hemispheres 1945.4
2156 Male, age 61, both hemispheres 1937.2
2463 Female, age 85, right hemisphere 1913.3
Medial periolivary nuclei
nTPM: 1967.5
2081 Male, age 80, both hemispheres 2027.1
2458 Female, age 91, both hemispheres 1996.7
2791 Male, age 74, right hemisphere 1974.6
2063 Male, age 76, both hemispheres 1945.6
2171 Female, age 85, both hemispheres 1893.5
Motor facial nucleus
nTPM: 1965.2
2697 Female, age 85, both hemispheres 2058.2
2365 Male, age 74, right hemisphere 2011.0
2795 Female, age 91, both hemispheres 1986.3
2126 Male, age 61, both hemispheres 1973.9
2062 Male, age 76, both hemispheres 1920.8
2327 Male, age 80, both hemispheres 1841.2
Motor trigeminal nucleus
nTPM: 1951.6
2321 Female, age 91, both hemispheres 1994.5
2560 Male, age 74, both hemispheres 1975.6
2335 Male, age 61, both hemispheres 1971.7
2309 Male, age 76, both hemispheres 1918.6
2079 Male, age 80, both hemispheres 1897.6
Nuclei of the trapezoid body
nTPM: 1922.3
1983 Male, age 76, both hemispheres 1990.7
2166 Male, age 80, both hemispheres 1936.0
2159 Male, age 61, both hemispheres 1908.4
2368 Female, age 91, both hemispheres 1906.2
2735 Female, age 85, both hemispheres 1870.2
Paramedian reticular nucleus
nTPM: 2031.2
2052 Male, age 76, both hemispheres 2174.1
2313 Male, age 61, both hemispheres 2010.5
2050 Female, age 85, both hemispheres 1980.9
2057 Male, age 80, both hemispheres 1959.4
Pontine nuclei
nTPM: 1968.6
2319 Female, age 91, both hemispheres 2071.4
2454 Male, age 74, left hemisphere 2019.2
2109 Female, age 72, unknown 1995.0
2115 Male, age 80, left hemisphere 1993.4
1863 Male, age 55, unknown 1951.6
1968 Male, age 76, left hemisphere 1917.5
2727 Male, age 61, right hemisphere 1907.8
2787 Female, age 85, both hemispheres 1893.3
Pontine raphe nucleus
nTPM: 1936.6
2853 Male, age 76, midline 1953.6
2122 Female, age 85, midline 1919.6
Posteroventral cochlear nucleus
nTPM: 2080.3
2341 Male, age 80, both hemispheres 2300.5
2135 Female, age 91, both hemispheres 2163.6
2371 Male, age 61, both hemispheres 2042.3
2752 Female, age 85, both hemispheres 1957.1
2070 Male, age 76, both hemispheres 1937.9
Principal sensory trigeminal nucleus
nTPM: 1934.9
2367 Female, age 91, left hemisphere 2006.5
2324 Male, age 76, both hemispheres 1943.3
2158 Male, age 61, both hemispheres 1904.3
2008 Male, age 80, left hemisphere 1885.5
Reticular pontine nucleus, caudal
nTPM: 1962.0
2457 Female, age 91, both hemispheres 2043.0
2559 Male, age 74, both hemispheres 2004.6
2092 Male, age 76, both hemispheres 1953.6
2332 Male, age 80, right hemisphere 1846.8
Reticular pontine nucleus, oral
nTPM: 1989.2
2361 Male, age 74, both hemispheres 2055.2
2366 Female, age 91, both hemispheres 2021.0
1939 Male, age 80, both hemispheres 1998.0
2167 Male, age 76, both hemispheres 1952.4
2012 Female, age 85, both hemispheres 1919.4
Reticulotegmental nucleus
nTPM: 1955.9
2322 Female, age 91, both hemispheres 2011.0
2452 Male, age 74, both hemispheres 1977.5
2333 Male, age 80, both hemispheres 1933.3
2325 Male, age 76, both hemispheres 1901.9
Spinal trigeminal nucleus, oral
nTPM: 1918.8
2164 Male, age 80, both hemispheres 1985.6
1978 Male, age 76, both hemispheres 1895.6
2737 Female, age 85, both hemispheres 1875.1
Subcoeruleus area
nTPM: 1959.1
2369 Female, age 85, left hemisphere 2027.3
2451 Male, age 74, both hemispheres 2000.8
1958 Male, age 80, both hemispheres 1970.4
2323 Female, age 91, left hemisphere 1921.9
2089 Male, age 76, left hemisphere 1874.9
Superior olive
nTPM: 1957.2
2364 Male, age 74, right hemisphere 1995.9
2020 Male, age 76, both hemispheres 1993.5
2561 Female, age 91, both hemispheres 1986.5
1875 Female, age 85, both hemispheres 1906.0
2329 Male, age 80, right hemisphere 1904.4
Superior vestibular nucleus
nTPM: 2059.6
2383 Male, age 74, both hemispheres 2125.4
2015 Male, age 80, both hemispheres 2080.2
2061 Male, age 76, both hemispheres 1973.1
Ventral periolivary nuclei
nTPM: 1953.5
2023 Male, age 76, both hemispheres 2006.0
2794 Female, age 91, left hemisphere 1988.4
2165 Male, age 80, both hemispheres 1926.2
2130 Female, age 85, both hemispheres 1893.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 1986.1
2840 Female, age 85, both hemispheres 2061.7
2359 Male, age 61, both hemispheres 2044.6
2161 Male, age 80, both hemispheres 2004.9
2456 Female, age 91, both hemispheres 1957.9
1959 Male, age 76, both hemispheres 1957.1
2449 Male, age 74, both hemispheres 1890.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 938.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 938.4
FF:10182-103D2 60 years, female 1043.0
FF:10165-103B3 76 years, female 833.8
Pons
Scaled Tags Per Million: 721.6
FF:10033-101E6 18-54 years, mixed 721.6

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 889.1
Pig sample Sample description nTPM
Pons
nTPM: 889.1
Samples: 4

Max nTPM: 1072.5
Min nTPM: 643.5
Sample A Female 816.3
Sample B Female 643.5
Sample C Male 1072.5
Sample D Male 1024.2

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 10.6
71378554 Antisense, RP_050517_01_A10, Mouse strain C57BL/6J (56 days, male) 10.6

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.