We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
WDR74
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • WDR74
BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:292.3 nTPM
HPA:292.3 nTPM
FANTOM5:28.2 Scaled Tags Per Million
Pig:50.6 nTPM
Mouse:34.1 nTPM
Allen mouse:1.5 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 292.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 231.8
1984 Male, age 76, both hemispheres 482.0
2301 Female, age 85, both hemispheres 246.4
2188 Female, age 91, both hemispheres 183.5
2090 Male, age 80, both hemispheres 15.3
Area postrema
nTPM: 47.0
2306 Male, age 80, both hemispheres 141.2
2054 Male, age 76, both hemispheres 0.0
2799 Male, age 61, both hemispheres 0.0
Cuneate nuclei
nTPM: 163.1
2376 Male, age 61, both hemispheres 287.3
2381 Male, age 80, both hemispheres 202.1
2131 Male, age 76, both hemispheres 0.0
Dorsal cochlear nucleus
nTPM: 142.4
2378 Male, age 80, both hemispheres 346.9
2370 Male, age 61, both hemispheres 261.8
2187 Female, age 91, both hemispheres 96.2
2058 Male, age 76, both hemispheres 7.3
2802 Male, age 74, right hemisphere 0.0
Dorsal medullary reticular nucleus
nTPM: 110.2
2373 Male, age 61, both hemispheres 284.0
2088 Male, age 76, both hemispheres 27.3
2040 Female, age 85, both hemispheres 19.4
Dorsal motor vagal complex
nTPM: 84.0
2000 Male, age 74, unknown 236.7
2185 Male, age 76, both hemispheres 236.2
2844 Male, age 55, unknown 172.8
2813 Female, age 72, unknown 22.7
2807 Female, age 85, both hemispheres 3.4
2133 Female, age 91, both hemispheres 0.0
2643 Male, age 74, both hemispheres 0.0
2797 Male, age 61, both hemispheres 0.0
Dorsal tegmental nucleus
nTPM: 148.9
2326 Male, age 74, both hemispheres 246.6
2358 Male, age 61, both hemispheres 138.3
1936 Male, age 76, left hemisphere 130.5
2083 Male, age 80, both hemispheres 80.3
Dorsolateral tegmental area
nTPM: 173.3
2360 Male, age 74, both hemispheres 693.6
2337 Male, age 61, both hemispheres 98.1
2751 Female, age 85, both hemispheres 75.0
2141 Male, age 76, both hemispheres 0.0
2654 Male, age 80, both hemispheres 0.0
Gigantocellular reticular nuclei, medullary
nTPM: 139.0
2314 Male, age 61, both hemispheres 221.4
2387 Female, age 91, both hemispheres 205.1
2462 Male, age 74, both hemispheres 152.2
2310 Male, age 80, both hemispheres 139.8
1876 Female, age 85, both hemispheres 115.5
2022 Male, age 76, right hemisphere 0.0
Gigantocellular reticular nuclei, pars
nTPM: 112.6
2168 Male, age 76, both hemispheres 196.0
2336 Male, age 61, both hemispheres 158.5
2330 Male, age 80, both hemispheres 112.2
2706 Male, age 80, both hemispheres 65.2
2084 Female, age 85, both hemispheres 31.0
Inferior olive
nTPM: 142.0
2178 Male, age 61, both hemispheres 243.3
2085 Female, age 85, both hemispheres 187.8
2379 Male, age 80, both hemispheres 168.2
2563 Male, age 74, both hemispheres 110.7
2628 Female, age 91, both hemispheres 0.0
Kolliker-Fuse nucleus
nTPM: 53.8
2793 Female, age 91, left hemisphere 114.5
2315 Male, age 76, right hemisphere 33.8
2163 Male, age 80, both hemispheres 13.2
Lateral lemniscal nuclei
nTPM: 147.6
2036 Male, age 80, both hemispheres 258.1
2169 Male, age 76, both hemispheres 171.4
2453 Male, age 74, right hemisphere 165.4
2746 Female, age 85, left hemisphere 71.7
2320 Female, age 91, left hemisphere 71.3
Lateral medullary reticular nucleus
nTPM: 124.2
2305 Male, age 74, both hemispheres 315.7
2374 Male, age 61, both hemispheres 278.8
2190 Female, age 85, both hemispheres 92.8
2852 Male, age 80, both hemispheres 41.3
2044 Male, age 76, both hemispheres 16.5
2804 Female, age 91, both hemispheres 0.0
Lateral parabrachial nucleus
nTPM: 52.6
2792 Male, age 76, both hemispheres 166.4
2013 Male, age 80, both hemispheres 24.6
2139 Female, age 85, right hemisphere 19.4
2790 Male, age 61, both hemispheres 0.0
Lateral vestibular nucleus
nTPM: 202.4
2184 Male, age 76, both hemispheres 259.5
2311 Male, age 80, both hemispheres 145.3
Locus coeruleus
nTPM: 124.4
2317 Female, age 72, unknown 326.2
2162 Male, age 80, both hemispheres 167.6
1980 Male, age 76, both hemispheres 160.4
2788 Male, age 74, unknown 159.7
2014 Male, age 55, unknown 46.9
2123 Female, age 91, both hemispheres 10.0
2720 Male, age 74, both hemispheres 0.0
Medial olivary nucleus
nTPM: 36.3
1962 Male, age 76, both hemispheres 101.1
2851 Male, age 80, both hemispheres 31.3
1943 Male, age 61, both hemispheres 12.9
2138 Female, age 91, both hemispheres 0.0
Medial parabrachial nucleus
nTPM: 52.4
2170 Female, age 91, both hemispheres 113.4
2156 Male, age 61, both hemispheres 77.2
2786 Male, age 76, both hemispheres 54.2
2463 Female, age 85, right hemisphere 9.4
2854 Male, age 80, both hemispheres 7.7
Medial periolivary nuclei
nTPM: 105.0
2171 Female, age 85, both hemispheres 241.3
2458 Female, age 91, both hemispheres 149.7
2063 Male, age 76, both hemispheres 52.6
2081 Male, age 80, both hemispheres 44.1
2791 Male, age 74, right hemisphere 37.4
Medial vestibular nucleus
nTPM: 34.2
2743 Female, age 85, both hemispheres 105.5
2801 Male, age 74, both hemispheres 67.0
2803 Female, age 91, both hemispheres 17.2
2093 Male, age 80, both hemispheres 15.5
2134 Male, age 76, both hemispheres 0.0
2624 Male, age 61, both hemispheres 0.0
Motor facial nucleus
nTPM: 106.6
2365 Male, age 74, right hemisphere 277.1
2697 Female, age 85, both hemispheres 130.8
2126 Male, age 61, both hemispheres 93.9
2327 Male, age 80, both hemispheres 70.1
2062 Male, age 76, both hemispheres 67.9
2795 Female, age 91, both hemispheres 0.0
Motor hypoglossal nucleus
nTPM: 2.2
2132 Female, age 85, both hemispheres 11.3
2125 Female, age 91, both hemispheres 0.0
2182 Male, age 80, both hemispheres 0.0
2277 Male, age 76, both hemispheres 0.0
2461 Male, age 61, both hemispheres 0.0
Motor trigeminal nucleus
nTPM: 88.7
2560 Male, age 74, both hemispheres 119.7
2335 Male, age 61, both hemispheres 96.2
2321 Female, age 91, both hemispheres 86.3
2309 Male, age 76, both hemispheres 78.7
2079 Male, age 80, both hemispheres 62.6
Nuclei of the trapezoid body
nTPM: 220.9
1983 Male, age 76, both hemispheres 306.9
2159 Male, age 61, both hemispheres 247.1
2368 Female, age 91, both hemispheres 240.7
2735 Female, age 85, both hemispheres 227.0
2166 Male, age 80, both hemispheres 82.7
Nucleus ambiguus
nTPM: 0.0
2071 Male, age 76, both hemispheres 0.0
2096 Female, age 85, both hemispheres 0.0
Nucleus cuneatus
nTPM: 95.1
2380 Male, age 80, both hemispheres 399.3
2564 Male, age 74, both hemispheres 124.9
2808 Female, age 85, both hemispheres 28.6
2562 Male, age 61, both hemispheres 17.9
2100 Male, age 76, both hemispheres 0.0
2805 Female, age 91, both hemispheres 0.0
Nucleus gracilis
nTPM: 123.4
2382 Male, age 80, both hemispheres 219.8
2299 Female, age 85, both hemispheres 100.9
2627 Male, age 74, both hemispheres 49.6
Nucleus raphe magnus
nTPM: 220.8
2455 Male, age 74, both hemispheres 452.6
2160 Male, age 61, both hemispheres 281.0
2459 Female, age 91, both hemispheres 265.8
2172 Female, age 85, both hemispheres 237.8
2328 Male, age 80, both hemispheres 75.9
2051 Male, age 76, both hemispheres 11.5
Nucleus raphe obscurus
nTPM: 5.4
2800 Male, age 61, midline 16.4
2142 Male, age 76, midline 0.0
2845 Female, age 85, midline 0.0
Nucleus raphe pallidus
nTPM: 37.4
1924 Male, age 61, midline 64.7
2183 Male, age 80, midline 47.5
2145 Male, age 76, midline 0.0
Nucleus tractus solitarii
nTPM: 78.7
2307 Male, age 80, both hemispheres 143.9
2656 Male, age 76, both hemispheres 88.5
2191 Female, age 85, both hemispheres 82.5
2144 Female, age 91, right hemisphere 0.0
Paramedian reticular nucleus
nTPM: 42.7
2313 Male, age 61, both hemispheres 98.5
2057 Male, age 80, both hemispheres 41.6
2052 Male, age 76, both hemispheres 30.7
2050 Female, age 85, both hemispheres 0.0
Parvicellular reticular nuclei
nTPM: 51.5
2558 Male, age 74, both hemispheres 61.4
2095 Male, age 76, both hemispheres 51.8
2119 Male, age 80, both hemispheres 41.4
Parvicellular reticular nuclei, medullary
nTPM: 92.5
2189 Female, age 91, both hemispheres 161.3
2181 Male, age 80, left hemisphere 116.3
2091 Female, age 85, both hemispheres 0.0
Peritrigeminal nucleus
nTPM: 79.4
2179 Male, age 61, both hemispheres 196.6
2136 Male, age 76, both hemispheres 22.4
2067 Female, age 85, both hemispheres 19.2
Pontine nuclei
nTPM: 168.3
2454 Male, age 74, left hemisphere 515.2
2727 Male, age 61, right hemisphere 263.8
1968 Male, age 76, left hemisphere 201.6
2319 Female, age 91, both hemispheres 182.0
2115 Male, age 80, left hemisphere 62.6
1863 Male, age 55, unknown 56.2
2787 Female, age 85, both hemispheres 53.8
2109 Female, age 72, unknown 11.5
Pontine raphe nucleus
nTPM: 85.3
2122 Female, age 85, midline 92.3
2853 Male, age 76, midline 78.4
Posteroventral cochlear nucleus
nTPM: 50.7
2371 Male, age 61, both hemispheres 155.1
2752 Female, age 85, both hemispheres 38.2
2135 Female, age 91, both hemispheres 32.9
2341 Male, age 80, both hemispheres 27.3
2070 Male, age 76, both hemispheres 0.0
Prepositus hypoglossal nucleus
nTPM: 16.5
2086 Male, age 80, both hemispheres 33.1
2855 Female, age 85, right hemisphere 0.0
Principal sensory trigeminal nucleus
nTPM: 199.5
2367 Female, age 91, left hemisphere 394.5
2158 Male, age 61, both hemispheres 156.6
2008 Male, age 80, left hemisphere 128.0
2324 Male, age 76, both hemispheres 118.8
Reticular pontine nucleus, caudal
nTPM: 136.1
2457 Female, age 91, both hemispheres 223.1
2559 Male, age 74, both hemispheres 139.5
2332 Male, age 80, right hemisphere 125.6
2092 Male, age 76, both hemispheres 56.1
Reticular pontine nucleus, oral
nTPM: 224.2
2361 Male, age 74, both hemispheres 524.4
2366 Female, age 91, both hemispheres 299.5
2167 Male, age 76, both hemispheres 171.2
2012 Female, age 85, both hemispheres 69.5
1939 Male, age 80, both hemispheres 56.2
Reticulotegmental nucleus
nTPM: 174.0
2452 Male, age 74, both hemispheres 299.1
2325 Male, age 76, both hemispheres 198.0
2333 Male, age 80, both hemispheres 121.4
2322 Female, age 91, both hemispheres 77.7
Spinal trigeminal nucleus, caudal
nTPM: 173.2
2447 Male, age 76, both hemispheres 269.1
2390 Female, age 91, both hemispheres 261.1
2312 Male, age 61, both hemispheres 158.5
2308 Male, age 80, both hemispheres 135.5
2642 Male, age 74, both hemispheres 41.9
Spinal trigeminal nucleus, interpolar
nTPM: 130.7
2389 Female, age 91, both hemispheres 285.8
2066 Male, age 76, right hemisphere 193.8
2386 Female, age 85, both hemispheres 173.8
2033 Male, age 80, both hemispheres 0.0
2625 Male, age 61, both hemispheres 0.0
Spinal trigeminal nucleus, oral
nTPM: 292.3
1978 Male, age 76, both hemispheres 613.6
2737 Female, age 85, both hemispheres 135.5
2164 Male, age 80, both hemispheres 127.9
Spinal vestibular nucleus
nTPM: 113.9
2748 Male, age 76, both hemispheres 304.4
2780 Male, age 80, both hemispheres 145.3
2186 Female, age 91, both hemispheres 123.3
2384 Male, age 74, both hemispheres 72.8
2806 Female, age 85, both hemispheres 30.4
2796 Male, age 61, both hemispheres 7.1
Subcoeruleus area
nTPM: 107.6
2451 Male, age 74, both hemispheres 315.1
2323 Female, age 91, left hemisphere 117.3
2089 Male, age 76, left hemisphere 61.6
1958 Male, age 80, both hemispheres 42.7
2369 Female, age 85, left hemisphere 1.2
Superior olive
nTPM: 246.8
2364 Male, age 74, right hemisphere 766.6
1875 Female, age 85, both hemispheres 160.4
2329 Male, age 80, right hemisphere 140.7
2020 Male, age 76, both hemispheres 105.7
2561 Female, age 91, both hemispheres 60.7
Superior vestibular nucleus
nTPM: 278.4
2383 Male, age 74, both hemispheres 682.4
2015 Male, age 80, both hemispheres 121.9
2061 Male, age 76, both hemispheres 31.1
Ventral medullary reticular nucleus
nTPM: 167.9
2372 Male, age 61, both hemispheres 298.2
2060 Male, age 76, both hemispheres 37.6
Ventral periolivary nuclei
nTPM: 52.1
2165 Male, age 80, both hemispheres 195.5
2794 Female, age 91, left hemisphere 13.0
2023 Male, age 76, both hemispheres 0.0
2130 Female, age 85, both hemispheres 0.0
Ventrolateral medulla, A1-C1 cell groups
nTPM: 93.4
2180 Male, age 61, both hemispheres 220.2
1986 Male, age 76, both hemispheres 109.1
2741 Female, age 85, both hemispheres 88.4
2302 Female, age 91, both hemispheres 49.2
2118 Male, age 80, both hemispheres 0.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 204.3
2449 Male, age 74, both hemispheres 348.8
2359 Male, age 61, both hemispheres 277.9
2161 Male, age 80, both hemispheres 245.3
2456 Female, age 91, both hemispheres 198.5
2840 Female, age 85, both hemispheres 82.6
1959 Male, age 76, both hemispheres 72.4

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 28.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 26.5
FF:10165-103B3 76 years, female 27.1
FF:10182-103D2 60 years, female 25.8
Medulla oblongata
Scaled Tags Per Million: 21.6
FF:10155-103A2 76 years, female 25.7
FF:10038-101F2 18-64 years, mixed 22.5
FF:10174-103C3 60 years, female 16.6
Pons
Scaled Tags Per Million: 28.2
FF:10033-101E6 18-54 years, mixed 28.2

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.6
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 45.1
Samples: 4

Max nTPM: 70.1
Min nTPM: 34.2
Sample A Female 37.4
Sample B Female 34.2
Sample C Male 38.8
Sample D Male 70.1
Pons
nTPM: 50.6
Samples: 4

Max nTPM: 62.4
Min nTPM: 36.4
Sample A Female 48.5
Sample B Female 36.4
Sample C Male 62.4
Sample D Male 55.2

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 34.1
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 34.1
Samples: 4

Max nTPM: 37.2
Min nTPM: 31.6
Sample A Male 33.9
Sample B Male 31.6
Sample C Female 33.6
Sample D Female 37.2

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.5
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 1.4
68341943 Antisense, RP_041207_02_E02, Mouse strain C57BL/6J (56 days, male) 1.4
Pons
Expression energy: 1.5
68341943 Antisense, RP_041207_02_E02, Mouse strain C57BL/6J (56 days, male) 1.5

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.