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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:258.8 nTPM
HPA:258.8 nTPM
GTEx:188.7 nTPM
FANTOM5:462.7 Scaled Tags Per Million
Pig:90.6 nTPM
Mouse:236.4 nTPM
Allen mouse:12.9 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 258.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 196.7
1827 Male, age 72, unknown 221.0
1870 Female, age 42, unknown 218.3
2411 Female, age 72, unknown 215.3
2666 Male, age 74, left hemisphere 200.4
1833 Male, age 53, unknown 196.9
2828 Female, age 72, unknown 196.4
1830 Male, age 51, unknown 188.8
2219 Male, age 76, both hemispheres 181.2
2586 Male, age 75, left hemisphere 178.4
2019 Male, age 18, unknown 169.8
Dorsal raphe nucleus
nTPM: 234.3
2298 Female, age 72, unknown 288.5
2047 Male, age 72, unknown 254.9
2750 Male, age 76, both hemispheres 216.5
1828 Male, age 53, unknown 211.4
2016 Female, age 72, unknown 200.3
Inferior colliculus
nTPM: 197.8
2097 Female, age 72, unknown 210.3
2849 Male, age 72, unknown 207.4
1848 Female, age 42, unknown 196.8
1890 Male, age 53, unknown 176.7
Median raphe nucleus
nTPM: 258.8
2220 Male, age 76, midline 258.8
Pedunculopontine tegmental nucleus
nTPM: 204.8
2334 Male, age 80, both hemispheres 216.2
1921 Female, age 85, both hemispheres 215.9
2338 Male, age 61, both hemispheres 182.3
Periaquaductal grey, anterior
nTPM: 220.0
1947 Male, age 18, unknown 250.6
1795 Male, age 51, unknown 215.7
2502 Female, age 75, unknown 193.8
Periaquaductal grey, dorsal
nTPM: 214.1
2850 Male, age 76, both hemispheres 250.4
1840 Male, age 53, unknown 229.6
2464 Female, age 72, unknown 194.7
1831 Male, age 72, unknown 181.8
Periaquaductal grey, lateral
nTPM: 213.7
2272 Male, age 74, both hemispheres 227.0
2053 Male, age 18, unknown 208.6
2140 Male, age 76, both hemispheres 205.3
Pretectal area
nTPM: 211.7
2224 Female, age 72, unknown 242.1
2825 Male, age 18, unknown 227.7
2273 Male, age 74, both hemispheres 226.8
2667 Female, age 75, unknown 220.0
1816 Male, age 51, unknown 217.9
1815 Male, age 53, unknown 213.2
1817 Female, age 42, unknown 211.1
1944 Female, age 72, unknown 211.1
2007 Male, age 72, unknown 206.0
2407 Male, age 75, both hemispheres 190.3
2316 Male, age 76, right hemisphere 162.7
Red nucleus
nTPM: 175.2
2725 Female, age 75, unknown 205.7
1821 Female, age 72, unknown 196.2
2584 Male, age 75, left hemisphere 180.0
1954 Female, age 42, unknown 177.2
1865 Male, age 51, unknown 174.8
2503 Female, age 72, unknown 174.6
1904 Male, age 53, unknown 171.9
2227 Male, age 72, unknown 168.8
2769 Male, age 72, unknown 167.7
2823 Male, age 76, right hemisphere 165.7
2588 Male, age 74, left hemisphere 160.2
2785 Male, age 18, unknown 158.9
Substantia nigra
nTPM: 211.7
1916 Female, age 42, unknown 235.0
2241 Male, age 72, unknown 233.5
1851 Male, age 51, unknown 223.3
1889 Female, age 72, unknown 216.2
1941 Male, age 53, unknown 216.1
2409 Female, age 72, unknown 213.8
2699 Male, age 18, unknown 206.9
2590 Female, age 75, unknown 195.3
2665 Male, age 74, both hemispheres 191.0
2583 Male, age 75, right hemisphere 186.2
Superior colliculus
nTPM: 190.7
2587 Male, age 74, left hemisphere 214.0
1796 Male, age 53, unknown 206.9
2261 Male, age 18, unknown 205.9
1839 Male, age 51, unknown 196.8
2087 Female, age 72, unknown 193.8
2668 Female, age 75, unknown 186.7
1895 Male, age 76, right hemisphere 181.2
1913 Female, age 42, unknown 180.2
1995 Male, age 72, unknown 171.3
2664 Male, age 75, both hemispheres 170.1
Ventral tegmental area
nTPM: 213.8
2410 Female, age 72, unknown 225.6
1915 Female, age 42, unknown 221.5
2218 Male, age 76, both hemispheres 216.2
2021 Male, age 53, unknown 215.5
2223 Female, age 72, unknown 206.7
1942 Male, age 51, unknown 197.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 188.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 188.7
Samples: 139

Max nTPM: 304.7
Min nTPM: 111.4
Std nTPM: 42.8
Median nTPM: 186.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 304.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 302.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 302.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 301.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 284.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 281.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 277.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 271.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 262.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 261.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 260.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 257.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 251.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 250.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 249.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 248.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 247.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 243.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 238.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 236.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 235.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 234.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 231.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 230.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 226.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 222.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 220.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 217.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 217.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 215.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 215.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 213.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 213.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 209.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 209.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 208.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 208.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 207.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 205.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 203.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 202.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 202.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 201.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 201.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 200.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 199.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 197.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 197.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 196.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 196.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 195.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 195.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 195.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 193.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 192.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 192.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 192.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 191.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 191.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 191.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 190.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 190.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 189.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 189.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 189.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 188.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 188.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 187.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 187.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 186.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 185.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 184.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 184.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 183.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 182.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 182.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 182.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 181.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 181.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 180.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 177.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 175.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 175.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 174.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 174.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 174.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 171.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 170.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 170.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 169.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 169.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 168.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 167.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 167.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 167.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 167.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 166.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 165.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 163.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 162.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 161.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 160.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 160.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 160.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 158.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 158.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 157.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 156.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 156.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 153.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 152.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 150.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 149.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 149.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 148.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 145.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 144.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 140.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 140.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 139.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 139.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 138.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 138.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 137.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 137.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 135.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 134.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 133.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 132.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 130.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 130.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 129.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 128.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 123.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 121.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 121.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 120.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 111.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 111.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 462.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 462.7
FF:10158-103A5 76 years, female 462.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 90.6
Pig sample Sample description nTPM
Midbrain
nTPM: 90.6
Samples: 4

Max nTPM: 112.7
Min nTPM: 78.1
Sample A Female 112.7
Sample B Female 84.1
Sample C Male 87.6
Sample D Male 78.1
Periaqueductal gray
nTPM: 85.5
Samples: 3

Max nTPM: 100.4
Min nTPM: 75.0
Sample B Female 81.1
Sample C Male 100.4
Sample D Male 75.0
Substantia nigra
nTPM: 89.1
Samples: 4

Max nTPM: 103.4
Min nTPM: 71.8
Sample A Female 103.4
Sample B Female 78.7
Sample C Male 102.4
Sample D Male 71.8
Superior colliculi
nTPM: 83.3
Samples: 4

Max nTPM: 91.0
Min nTPM: 70.1
Sample A Female 91.0
Sample B Female 85.6
Sample C Male 86.3
Sample D Male 70.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 236.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 236.4
Samples: 4

Max nTPM: 251.1
Min nTPM: 225.7
Sample A Male 242.3
Sample B Male 226.3
Sample C Female 225.7
Sample D Female 251.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.9
686217 Antisense, RP_040916_01_C03, Mouse strain C57BL/6J (56 days, male) 13.2
70743884 Antisense, RP_050725_01_H08, Mouse strain C57BL/6J (56 days, male) 12.6

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