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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:155.4 nTPM
HPA:155.4 nTPM
GTEx:178.0 nTPM
FANTOM5:93.8 Scaled Tags Per Million
Pig:24.0 nTPM
Mouse:147.3 nTPM
Allen mouse:3.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 155.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 149.1
2019 Male, age 18, unknown 160.4
2411 Female, age 72, unknown 155.0
1870 Female, age 42, unknown 152.2
1827 Male, age 72, unknown 149.5
2586 Male, age 75, left hemisphere 147.6
1833 Male, age 53, unknown 147.4
2219 Male, age 76, both hemispheres 145.3
1830 Male, age 51, unknown 145.2
2666 Male, age 74, left hemisphere 145.1
2828 Female, age 72, unknown 143.7
Dorsal raphe nucleus
nTPM: 155.4
2298 Female, age 72, unknown 166.0
1828 Male, age 53, unknown 155.1
2750 Male, age 76, both hemispheres 153.4
2047 Male, age 72, unknown 152.2
2016 Female, age 72, unknown 150.1
Inferior colliculus
nTPM: 149.9
2097 Female, age 72, unknown 158.0
1890 Male, age 53, unknown 150.4
1848 Female, age 42, unknown 147.4
2849 Male, age 72, unknown 143.8
Median raphe nucleus
nTPM: 153.2
2220 Male, age 76, midline 153.2
Pedunculopontine tegmental nucleus
nTPM: 154.9
2334 Male, age 80, both hemispheres 157.9
1921 Female, age 85, both hemispheres 154.1
2338 Male, age 61, both hemispheres 152.7
Periaquaductal grey, anterior
nTPM: 148.5
1947 Male, age 18, unknown 148.9
1795 Male, age 51, unknown 148.3
2502 Female, age 75, unknown 148.2
Periaquaductal grey, dorsal
nTPM: 149.3
2850 Male, age 76, both hemispheres 154.4
2464 Female, age 72, unknown 149.3
1840 Male, age 53, unknown 147.3
1831 Male, age 72, unknown 146.1
Periaquaductal grey, lateral
nTPM: 147.0
2272 Male, age 74, both hemispheres 149.7
2140 Male, age 76, both hemispheres 146.1
2053 Male, age 18, unknown 145.2
Pretectal area
nTPM: 153.6
1817 Female, age 42, unknown 160.7
2007 Male, age 72, unknown 160.0
1944 Female, age 72, unknown 158.3
1816 Male, age 51, unknown 157.7
2667 Female, age 75, unknown 155.2
2273 Male, age 74, both hemispheres 155.1
2224 Female, age 72, unknown 154.6
1815 Male, age 53, unknown 154.4
2316 Male, age 76, right hemisphere 149.5
2825 Male, age 18, unknown 144.1
2407 Male, age 75, both hemispheres 139.7
Red nucleus
nTPM: 152.8
1821 Female, age 72, unknown 167.1
1865 Male, age 51, unknown 155.7
2503 Female, age 72, unknown 154.9
1904 Male, age 53, unknown 154.4
2785 Male, age 18, unknown 154.4
2725 Female, age 75, unknown 154.0
2769 Male, age 72, unknown 153.4
1954 Female, age 42, unknown 152.6
2227 Male, age 72, unknown 152.5
2823 Male, age 76, right hemisphere 151.7
2588 Male, age 74, left hemisphere 141.7
2584 Male, age 75, left hemisphere 140.9
Substantia nigra
nTPM: 153.5
1889 Female, age 72, unknown 161.5
1851 Male, age 51, unknown 159.1
1916 Female, age 42, unknown 158.7
2241 Male, age 72, unknown 158.3
1941 Male, age 53, unknown 154.0
2409 Female, age 72, unknown 150.2
2699 Male, age 18, unknown 149.9
2665 Male, age 74, both hemispheres 149.1
2590 Female, age 75, unknown 148.1
2583 Male, age 75, right hemisphere 146.4
Superior colliculus
nTPM: 150.0
1796 Male, age 53, unknown 152.9
1913 Female, age 42, unknown 152.7
2587 Male, age 74, left hemisphere 152.5
2261 Male, age 18, unknown 151.5
2668 Female, age 75, unknown 151.3
1895 Male, age 76, right hemisphere 150.9
2087 Female, age 72, unknown 150.2
1995 Male, age 72, unknown 149.4
1839 Male, age 51, unknown 146.7
2664 Male, age 75, both hemispheres 142.2
Ventral tegmental area
nTPM: 154.9
2410 Female, age 72, unknown 162.9
1915 Female, age 42, unknown 157.9
2218 Male, age 76, both hemispheres 155.2
2223 Female, age 72, unknown 154.2
1942 Male, age 51, unknown 149.6
2021 Male, age 53, unknown 149.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 178.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 178.0
Samples: 139

Max nTPM: 287.8
Min nTPM: 111.6
Std nTPM: 32.6
Median nTPM: 173.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 287.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 280.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 269.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 269.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 266.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 254.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 250.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 242.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 242.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 237.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 235.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 234.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 232.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 232.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 223.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 223.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 220.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 213.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 211.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 208.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 205.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 204.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 203.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 202.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 199.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 198.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 194.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 194.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 193.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 192.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 191.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 189.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 187.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 187.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 187.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 187.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 187.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 185.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 185.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 184.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 184.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 184.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 183.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 182.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 182.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 182.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 182.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 182.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 181.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 181.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 181.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 180.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 179.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 179.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 178.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 178.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 177.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 177.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 177.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 177.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 176.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 175.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 175.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 175.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 174.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 174.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 174.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 174.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 174.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 173.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 173.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 172.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 171.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 171.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 170.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 170.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 169.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 169.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 168.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 168.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 168.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 168.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 168.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 168.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 168.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 167.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 166.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 166.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 165.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 164.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 164.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 164.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 164.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 163.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 163.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 163.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 162.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 162.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 161.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 161.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 159.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 159.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 158.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 158.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 158.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 158.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 157.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 155.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 155.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 155.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 155.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 153.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 152.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 151.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 151.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 150.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 150.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 150.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 149.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 148.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 146.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 146.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 145.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 144.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 144.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 142.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 141.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 141.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 141.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 140.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 138.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 136.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 135.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 131.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 126.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 126.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 123.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 120.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 111.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 93.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 93.8
FF:10158-103A5 76 years, female 93.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 24.0
Pig sample Sample description nTPM
Midbrain
nTPM: 22.8
Samples: 4

Max nTPM: 30.1
Min nTPM: 18.6
Sample A Female 30.1
Sample B Female 22.7
Sample C Male 19.9
Sample D Male 18.6
Periaqueductal gray
nTPM: 20.0
Samples: 3

Max nTPM: 20.3
Min nTPM: 19.6
Sample B Female 20.0
Sample C Male 19.6
Sample D Male 20.3
Substantia nigra
nTPM: 21.3
Samples: 4

Max nTPM: 29.6
Min nTPM: 18.3
Sample A Female 29.6
Sample B Female 18.9
Sample C Male 18.4
Sample D Male 18.3
Superior colliculi
nTPM: 24.0
Samples: 4

Max nTPM: 28.5
Min nTPM: 21.3
Sample A Female 28.5
Sample B Female 24.5
Sample C Male 21.3
Sample D Male 21.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 147.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 147.3
Samples: 4

Max nTPM: 151.3
Min nTPM: 144.1
Sample A Male 151.3
Sample B Male 146.3
Sample C Female 144.1
Sample D Female 147.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.3
69134163 Antisense, RP_050321_02_D10, Mouse strain C57BL/6J (56 days, male) 3.3

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