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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA061250
Pigment epithelial cells
Not detected
Photoreceptor cells
Medium
Limiting membrane
Not detected
Outer plexiform layer
Low
Inner nuclear layer
Low
Inner plexiform layer
Low
Ganglion cells
Medium
Nerve fiber layer
Low
RETINA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA063127
Pigment epithelial cells
Not detected
Photoreceptor cells
Medium
Limiting membrane
Not detected
Outer plexiform layer
Low
Inner nuclear layer
Not detected
Inner plexiform layer
Not detected
Ganglion cells
Not detected
Nerve fiber layer
Not detected
RETINA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 122.8
Min nTPM: 48.0
Std nTPM: 13.5
Median nTPM:
415_1
77 years, female
122.8
490_1
67 years, female
105.8
414_1
84 years, female
101.8
137_1
83 years, male
100.2
117_1
61 years, male
99.4
466_1
57 years, female
97.6
324_1
76 years, male
95.1
172_1
72 years, female
93.0
425_1
59 years, female
92.1
246_1
77 years, male
92.0
32_1
67 years, male
91.9
468_1
89 years, male
91.9
347_1
72 years, male
91.8
526_1
61 years, male
91.4
217_1
76 years, male
90.6
35_1
74 years, female
89.4
499_1
55 years, female
88.5
99_1
64 years, male
88.2
237_1
82 years, male
87.8
9_1
66 years, female
87.1
313_1
79 years, female
86.4
311_1
78 years, male
85.4
405_1
91 years, male
85.0
149_1
88 years, male
84.7
42_1
85 years, male
84.4
229_1
69 years, female
84.2
43_1
64 years, female
84.0
115_1
83 years, male
83.1
6_1
73 years, female
82.5
18_1
88 years, male
82.3
81_1
67 years, male
82.1
162_1
79 years, female
82.0
518_1
75 years, female
81.6
495_1
57 years, female
81.3
251_1
78 years, male
81.0
119_1
70 years, female
80.5
389_1
86 years, female
80.4
89_1
63 years, male
79.7
375_1
74 years, female
79.3
126_1
63 years, male
78.9
503_1
68 years, male
78.7
266_1
85 years, male
77.4
413_1
59 years, female
77.3
315_1
62 years, female
77.1
491_1
89 years, female
77.0
142_1
61 years, female
75.8
406_1
79 years, male
75.7
307_1
66 years, female
74.7
335_1
73 years, female
73.7
350_1
84 years, female
73.4
109_1
81 years, female
73.3
177_1
74 years, male
73.3
265_1
87 years, male
73.0
447_1
81 years, male
72.8
145_1
84 years, male
72.5
173_1
67 years, male
71.7
355_1
70 years, female
71.4
264_1
73 years, female
71.2
321_1
62 years, female
70.7
352_1
62 years, male
70.7
153_1
70 years, female
70.4
120_1
70 years, female
70.2
286_1
68 years, female
69.8
319_1
81 years, male
69.5
386_1
76 years, male
69.4
189_1
76 years, male
69.3
254_1
77 years, female
69.3
517_1
88 years, male
69.0
480_1
63 years, male
68.9
17_1
71 years, male
68.7
292_1
71 years, male
68.2
293_1
68 years, female
67.5
139_1
64 years, female
67.1
243_1
75 years, male
67.1
351_1
91 years, male
67.1
348_1
84 years, male
66.8
394_1
75 years, female
66.3
318_1
68 years, male
66.2
316_1
62 years, male
65.3
376_1
75 years, female
64.9
396_1
62 years, male
64.7
322_1
76 years, male
64.0
314_1
67 years, male
63.6
353_1
82 years, female
63.3
288_1
66 years, female
63.1
163_1
78 years, male
62.0
377_1
82 years, female
61.6
320_1
89 years, female
61.5
291_1
76 years, male
60.8
501_1
88 years, male
60.7
349_1
83 years, male
60.4
218_1
71 years, female
59.6
384_1
83 years, male
59.5
317_1
60 years, male
58.7
4_1
88 years, female
56.8
356_1
87 years, female
56.8
404_1
82 years, female
56.3
41_1
94 years, female
56.0
354_1
81 years, female
55.4
295_1
61 years, female
55.2
506_1
65 years, male
55.2
308_1
70 years, female
54.2
2_1
77 years, female
48.2
452_1
88 years, female
48.2
379_1
60 years, male
48.0
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
