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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:186.2 nTPM
HPA:186.2 nTPM
GTEx:134.2 nTPM
FANTOM5:138.8 Scaled Tags Per Million
Pig:193.2 nTPM
Mouse:168.8 nTPM
Allen mouse:4.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 186.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 156.1
2586 Male, age 75, left hemisphere 233.7
2828 Female, age 72, unknown 196.5
2666 Male, age 74, left hemisphere 177.0
1827 Male, age 72, unknown 174.3
1870 Female, age 42, unknown 160.9
1833 Male, age 53, unknown 139.6
2411 Female, age 72, unknown 132.4
1830 Male, age 51, unknown 130.2
2219 Male, age 76, both hemispheres 123.3
2019 Male, age 18, unknown 93.6
Dorsal raphe nucleus
nTPM: 175.4
2047 Male, age 72, unknown 210.2
2016 Female, age 72, unknown 183.0
2298 Female, age 72, unknown 177.9
1828 Male, age 53, unknown 161.8
2750 Male, age 76, both hemispheres 144.4
Inferior colliculus
nTPM: 144.7
2849 Male, age 72, unknown 171.4
1848 Female, age 42, unknown 154.4
1890 Male, age 53, unknown 129.2
2097 Female, age 72, unknown 123.6
Median raphe nucleus
nTPM: 152.0
2220 Male, age 76, midline 152.0
Pedunculopontine tegmental nucleus
nTPM: 126.8
2334 Male, age 80, both hemispheres 138.9
1921 Female, age 85, both hemispheres 138.3
2338 Male, age 61, both hemispheres 103.1
Periaquaductal grey, anterior
nTPM: 186.2
1795 Male, age 51, unknown 190.7
1947 Male, age 18, unknown 187.4
2502 Female, age 75, unknown 180.5
Periaquaductal grey, dorsal
nTPM: 180.6
1840 Male, age 53, unknown 209.1
2850 Male, age 76, both hemispheres 187.2
2464 Female, age 72, unknown 166.5
1831 Male, age 72, unknown 159.6
Periaquaductal grey, lateral
nTPM: 186.2
2053 Male, age 18, unknown 222.0
2140 Male, age 76, both hemispheres 192.0
2272 Male, age 74, both hemispheres 144.5
Pretectal area
nTPM: 151.1
2825 Male, age 18, unknown 202.0
2224 Female, age 72, unknown 183.4
2667 Female, age 75, unknown 153.0
2273 Male, age 74, both hemispheres 152.0
2407 Male, age 75, both hemispheres 150.4
1816 Male, age 51, unknown 149.5
2316 Male, age 76, right hemisphere 140.1
1815 Male, age 53, unknown 139.5
1944 Female, age 72, unknown 139.2
1817 Female, age 42, unknown 132.9
2007 Male, age 72, unknown 119.7
Red nucleus
nTPM: 122.5
2725 Female, age 75, unknown 134.6
2503 Female, age 72, unknown 131.3
2588 Male, age 74, left hemisphere 129.4
2227 Male, age 72, unknown 129.1
2584 Male, age 75, left hemisphere 128.4
2769 Male, age 72, unknown 126.6
1821 Female, age 72, unknown 121.3
1904 Male, age 53, unknown 120.4
1865 Male, age 51, unknown 120.1
1954 Female, age 42, unknown 118.9
2823 Male, age 76, right hemisphere 114.0
2785 Male, age 18, unknown 96.5
Substantia nigra
nTPM: 136.3
2699 Male, age 18, unknown 167.1
2665 Male, age 74, both hemispheres 160.9
1916 Female, age 42, unknown 143.8
2590 Female, age 75, unknown 137.8
2583 Male, age 75, right hemisphere 137.2
1889 Female, age 72, unknown 132.4
1851 Male, age 51, unknown 130.9
1941 Male, age 53, unknown 128.1
2409 Female, age 72, unknown 115.8
2241 Male, age 72, unknown 109.4
Superior colliculus
nTPM: 159.6
2664 Male, age 75, both hemispheres 233.7
2261 Male, age 18, unknown 176.1
1796 Male, age 53, unknown 172.5
1839 Male, age 51, unknown 166.8
1995 Male, age 72, unknown 150.9
2087 Female, age 72, unknown 144.8
2587 Male, age 74, left hemisphere 144.4
2668 Female, age 75, unknown 138.2
1913 Female, age 42, unknown 137.3
1895 Male, age 76, right hemisphere 130.9
Ventral tegmental area
nTPM: 145.4
2021 Male, age 53, unknown 166.8
1942 Male, age 51, unknown 160.2
1915 Female, age 42, unknown 147.4
2218 Male, age 76, both hemispheres 135.5
2223 Female, age 72, unknown 131.5
2410 Female, age 72, unknown 131.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 134.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 134.2
Samples: 139

Max nTPM: 361.0
Min nTPM: 30.2
Std nTPM: 59.1
Median nTPM: 123.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 361.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 346.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 305.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 289.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 282.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 259.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 245.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 244.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 242.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 233.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 232.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 227.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 220.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 216.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 201.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 199.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 199.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 196.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 193.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 192.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 186.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 185.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 183.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 180.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 178.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 173.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 170.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 170.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 170.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 169.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 168.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 167.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 161.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 160.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 157.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 156.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 156.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 155.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 154.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 153.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 153.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 151.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 150.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 149.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 148.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 147.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 146.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 144.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 144.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 144.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 144.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 143.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 142.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 141.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 140.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 140.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 139.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 133.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 130.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 130.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 127.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 127.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 126.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 126.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 126.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 126.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 126.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 125.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 124.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 123.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 122.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 122.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 120.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 120.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 120.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 120.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 119.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 118.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 117.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 117.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 115.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 114.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 113.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 113.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 113.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 111.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 111.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 111.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 109.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 109.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 108.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 108.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 108.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 107.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 106.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 106.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 103.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 103.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 103.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 98.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 96.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 95.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 95.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 95.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 91.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 89.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 89.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 88.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 87.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 86.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 83.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 82.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 80.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 80.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 77.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 76.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 74.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 73.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 72.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 71.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 69.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 68.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 68.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 66.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 66.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 64.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 63.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 62.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 60.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 59.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 58.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 54.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 50.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 33.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 30.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 138.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 138.8
FF:10158-103A5 76 years, female 138.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 193.2
Pig sample Sample description nTPM
Midbrain
nTPM: 179.7
Samples: 4

Max nTPM: 206.6
Min nTPM: 156.4
Sample A Female 206.6
Sample B Female 196.0
Sample C Male 156.4
Sample D Male 159.7
Periaqueductal gray
nTPM: 193.2
Samples: 3

Max nTPM: 208.2
Min nTPM: 169.6
Sample B Female 208.2
Sample C Male 201.9
Sample D Male 169.6
Substantia nigra
nTPM: 191.4
Samples: 4

Max nTPM: 202.5
Min nTPM: 179.8
Sample A Female 198.7
Sample B Female 179.8
Sample C Male 202.5
Sample D Male 184.7
Superior colliculi
nTPM: 144.0
Samples: 4

Max nTPM: 168.5
Min nTPM: 104.1
Sample A Female 164.8
Sample B Female 104.1
Sample C Male 138.4
Sample D Male 168.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 168.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 168.8
Samples: 4

Max nTPM: 178.2
Min nTPM: 159.5
Sample A Male 178.2
Sample B Male 159.5
Sample C Female 174.4
Sample D Female 163.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.2
69015290 Antisense, RP_050310_02_F08, Mouse strain C57BL/6J (56 days, male) 4.2

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