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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA074923
Pigment epithelial cells
Not detected
Photoreceptor cells
Low
Limiting membrane
Not detected
Outer plexiform layer
Not detected
Inner nuclear layer
High
Inner plexiform layer
Not detected
Ganglion cells
High
Nerve fiber layer
Not detected
RETINA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA075573
Pigment epithelial cells
Not detected
Photoreceptor cells
High
Limiting membrane
Not detected
Outer plexiform layer
Not detected
Inner nuclear layer
Low
Inner plexiform layer
Not detected
Ganglion cells
Not detected
Nerve fiber layer
Not detected
RETINA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 251.2
Min nTPM: 18.1
Std nTPM: 47.5
Median nTPM:
352_1
62 years, male
251.2
356_1
87 years, female
207.8
218_1
71 years, female
203.5
237_1
82 years, male
203.5
355_1
70 years, female
197.6
354_1
81 years, female
191.0
349_1
83 years, male
188.4
394_1
75 years, female
183.6
172_1
72 years, female
173.4
350_1
84 years, female
172.6
163_1
78 years, male
172.4
375_1
74 years, female
167.3
243_1
75 years, male
167.0
319_1
81 years, male
152.9
353_1
82 years, female
150.3
286_1
68 years, female
149.7
292_1
71 years, male
148.6
99_1
64 years, male
146.3
335_1
73 years, female
145.8
447_1
81 years, male
144.8
229_1
69 years, female
144.3
379_1
60 years, male
144.2
452_1
88 years, female
143.9
347_1
72 years, male
142.7
503_1
68 years, male
141.8
386_1
76 years, male
140.4
506_1
65 years, male
138.2
351_1
91 years, male
136.5
177_1
74 years, male
132.7
320_1
89 years, female
132.1
425_1
59 years, female
132.0
376_1
75 years, female
131.6
389_1
86 years, female
129.3
318_1
68 years, male
126.8
264_1
73 years, female
126.5
377_1
82 years, female
120.6
384_1
83 years, male
118.4
406_1
79 years, male
118.2
291_1
76 years, male
118.1
293_1
68 years, female
117.3
217_1
76 years, male
112.5
266_1
85 years, male
109.8
251_1
78 years, male
109.0
517_1
88 years, male
108.2
246_1
77 years, male
107.7
265_1
87 years, male
107.6
35_1
74 years, female
104.7
499_1
55 years, female
103.8
404_1
82 years, female
103.6
348_1
84 years, male
103.4
189_1
76 years, male
103.3
316_1
62 years, male
102.7
321_1
62 years, female
101.9
396_1
62 years, male
101.8
295_1
61 years, female
101.0
173_1
67 years, male
100.4
317_1
60 years, male
98.2
468_1
89 years, male
96.3
526_1
61 years, male
95.7
42_1
85 years, male
94.4
405_1
91 years, male
94.0
313_1
79 years, female
90.6
9_1
66 years, female
90.0
254_1
77 years, female
88.2
324_1
76 years, male
85.9
480_1
63 years, male
85.1
115_1
83 years, male
83.0
137_1
83 years, male
80.6
6_1
73 years, female
77.9
314_1
67 years, male
74.4
322_1
76 years, male
74.0
311_1
78 years, male
73.1
518_1
75 years, female
72.8
32_1
67 years, male
72.5
126_1
63 years, male
72.2
142_1
61 years, female
71.0
153_1
70 years, female
70.0
415_1
77 years, female
67.7
288_1
66 years, female
66.6
109_1
81 years, female
66.2
315_1
62 years, female
66.1
117_1
61 years, male
65.4
120_1
70 years, female
64.4
81_1
67 years, male
62.7
18_1
88 years, male
62.3
4_1
88 years, female
60.4
162_1
79 years, female
57.1
17_1
71 years, male
56.5
145_1
84 years, male
56.3
307_1
66 years, female
52.9
466_1
57 years, female
52.0
119_1
70 years, female
50.9
43_1
64 years, female
50.7
414_1
84 years, female
49.9
41_1
94 years, female
47.2
2_1
77 years, female
39.4
139_1
64 years, female
39.2
89_1
63 years, male
38.9
490_1
67 years, female
37.3
501_1
88 years, male
34.5
149_1
88 years, male
34.4
495_1
57 years, female
30.5
308_1
70 years, female
26.0
413_1
59 years, female
19.6
491_1
89 years, female
18.1
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
