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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 75.4
Min nTPM: 14.4
Std nTPM: 14.0
Median nTPM:
139_1
64 years, female
75.4
89_1
63 years, male
71.2
42_1
85 years, male
66.6
491_1
89 years, female
65.7
119_1
70 years, female
61.8
149_1
88 years, male
60.7
35_1
74 years, female
59.3
142_1
61 years, female
58.2
495_1
57 years, female
57.6
162_1
79 years, female
57.5
120_1
70 years, female
56.0
137_1
83 years, male
55.3
4_1
88 years, female
55.2
17_1
71 years, male
54.5
2_1
77 years, female
52.4
81_1
67 years, male
52.4
109_1
81 years, female
52.3
99_1
64 years, male
51.8
145_1
84 years, male
51.6
126_1
63 years, male
51.2
308_1
70 years, female
50.6
501_1
88 years, male
50.5
490_1
67 years, female
50.1
117_1
61 years, male
49.7
153_1
70 years, female
49.3
32_1
67 years, male
49.0
217_1
76 years, male
48.1
43_1
64 years, female
47.8
18_1
88 years, male
47.5
41_1
94 years, female
47.1
314_1
67 years, male
45.5
415_1
77 years, female
45.5
315_1
62 years, female
44.2
6_1
73 years, female
42.7
322_1
76 years, male
42.7
311_1
78 years, male
42.4
9_1
66 years, female
41.0
518_1
75 years, female
40.4
466_1
57 years, female
39.2
115_1
83 years, male
38.7
307_1
66 years, female
38.3
348_1
84 years, male
38.0
316_1
62 years, male
36.5
288_1
66 years, female
36.0
291_1
76 years, male
35.9
447_1
81 years, male
35.7
324_1
76 years, male
35.2
254_1
77 years, female
34.6
499_1
55 years, female
34.4
396_1
62 years, male
34.3
320_1
89 years, female
34.0
265_1
87 years, male
33.7
313_1
79 years, female
33.0
468_1
89 years, male
32.9
503_1
68 years, male
32.3
295_1
61 years, female
32.2
413_1
59 years, female
31.9
347_1
72 years, male
31.5
251_1
78 years, male
30.9
293_1
68 years, female
29.6
526_1
61 years, male
29.3
317_1
60 years, male
29.2
480_1
63 years, male
29.0
354_1
81 years, female
28.5
351_1
91 years, male
28.2
355_1
70 years, female
28.1
517_1
88 years, male
27.9
335_1
73 years, female
27.8
356_1
87 years, female
27.5
506_1
65 years, male
27.5
266_1
85 years, male
27.3
173_1
67 years, male
26.6
350_1
84 years, female
26.5
389_1
86 years, female
26.3
353_1
82 years, female
25.7
321_1
62 years, female
25.6
384_1
83 years, male
25.6
264_1
73 years, female
25.1
377_1
82 years, female
24.8
286_1
68 years, female
24.7
318_1
68 years, male
24.7
319_1
81 years, male
24.2
352_1
62 years, male
24.0
292_1
71 years, male
23.7
375_1
74 years, female
23.7
452_1
88 years, female
23.6
349_1
83 years, male
23.4
237_1
82 years, male
23.3
243_1
75 years, male
22.3
376_1
75 years, female
22.0
386_1
76 years, male
22.0
405_1
91 years, male
21.9
379_1
60 years, male
21.5
394_1
75 years, female
21.5
414_1
84 years, female
20.6
172_1
72 years, female
19.9
246_1
77 years, male
19.9
229_1
69 years, female
19.8
406_1
79 years, male
18.9
404_1
82 years, female
18.8
425_1
59 years, female
18.4
189_1
76 years, male
18.0
218_1
71 years, female
15.3
177_1
74 years, male
15.0
163_1
78 years, male
14.4
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
