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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA037675
Intestine, exocrine pancreas, urothelial cells, uterine gland, breast and trophoblastic cells displayed strong cytoplasmic staining with membranous positivity in fallopian tube. Nasopharynx, salivary gland, thyroid, pararthyroid, renal tubules and subset of immune cells were moderately immunoreactive. Remaining normal tissues were weakly stained or negative.
HPA037676
Most normal tissues showed weak to moderate cytoplasmic positivity with additional membranous staining in glandular tissues. Muscle tissues, respiratory epithelial cells, fallopian tubes, small intestine and glandular cells in breast displayed strong immunoreactivity. Lung, hepatocytes, islet of Langerhans, stromal cells in uterus, cells in CNS and adipocytes were generally negative.
CAB010345
Normal tissues generally displayed moderate cytoplasmic immunoreactivity. Strong staining was for example observed in the intestine, gallbladder and adrenal gland.