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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:44.1 nTPM
HPA:44.1 nTPM
GTEx:38.5 nTPM
FANTOM5:32.1 Scaled Tags Per Million
Pig:29.0 nTPM
Mouse:43.2 nTPM
Allen mouse:7.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 44.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 40.5
2586 Male, age 75, left hemisphere 50.0
2828 Female, age 72, unknown 42.8
2219 Male, age 76, both hemispheres 41.5
1870 Female, age 42, unknown 40.1
2666 Male, age 74, left hemisphere 39.9
2019 Male, age 18, unknown 39.1
1830 Male, age 51, unknown 38.4
2411 Female, age 72, unknown 38.4
1833 Male, age 53, unknown 37.8
1827 Male, age 72, unknown 36.8
Dorsal raphe nucleus
nTPM: 41.0
2016 Female, age 72, unknown 45.5
2047 Male, age 72, unknown 40.8
1828 Male, age 53, unknown 39.8
2298 Female, age 72, unknown 39.6
2750 Male, age 76, both hemispheres 39.4
Inferior colliculus
nTPM: 37.9
2849 Male, age 72, unknown 40.1
1890 Male, age 53, unknown 39.1
2097 Female, age 72, unknown 36.6
1848 Female, age 42, unknown 35.6
Median raphe nucleus
nTPM: 35.5
2220 Male, age 76, midline 35.5
Pedunculopontine tegmental nucleus
nTPM: 36.9
1921 Female, age 85, both hemispheres 39.7
2334 Male, age 80, both hemispheres 36.8
2338 Male, age 61, both hemispheres 34.1
Periaquaductal grey, anterior
nTPM: 44.1
1947 Male, age 18, unknown 44.8
1795 Male, age 51, unknown 43.8
2502 Female, age 75, unknown 43.8
Periaquaductal grey, dorsal
nTPM: 40.0
2850 Male, age 76, both hemispheres 42.6
1840 Male, age 53, unknown 40.4
2464 Female, age 72, unknown 39.8
1831 Male, age 72, unknown 37.0
Periaquaductal grey, lateral
nTPM: 43.5
2272 Male, age 74, both hemispheres 46.9
2140 Male, age 76, both hemispheres 46.1
2053 Male, age 18, unknown 37.4
Pretectal area
nTPM: 40.4
2273 Male, age 74, both hemispheres 48.3
2007 Male, age 72, unknown 41.9
2224 Female, age 72, unknown 41.4
2316 Male, age 76, right hemisphere 41.3
2407 Male, age 75, both hemispheres 40.0
1944 Female, age 72, unknown 39.5
1815 Male, age 53, unknown 39.4
2825 Male, age 18, unknown 39.3
2667 Female, age 75, unknown 39.1
1816 Male, age 51, unknown 37.7
1817 Female, age 42, unknown 36.8
Red nucleus
nTPM: 38.6
2769 Male, age 72, unknown 43.4
2785 Male, age 18, unknown 42.4
2227 Male, age 72, unknown 42.0
2588 Male, age 74, left hemisphere 40.5
2584 Male, age 75, left hemisphere 40.2
2503 Female, age 72, unknown 38.8
2725 Female, age 75, unknown 38.1
1904 Male, age 53, unknown 37.7
1865 Male, age 51, unknown 36.1
1954 Female, age 42, unknown 36.1
2823 Male, age 76, right hemisphere 34.4
1821 Female, age 72, unknown 33.7
Substantia nigra
nTPM: 38.9
1916 Female, age 42, unknown 42.0
1851 Male, age 51, unknown 41.2
2699 Male, age 18, unknown 41.0
1941 Male, age 53, unknown 40.8
2583 Male, age 75, right hemisphere 40.0
2665 Male, age 74, both hemispheres 39.7
2590 Female, age 75, unknown 39.5
1889 Female, age 72, unknown 37.8
2241 Male, age 72, unknown 34.3
2409 Female, age 72, unknown 33.0
Superior colliculus
nTPM: 39.3
2664 Male, age 75, both hemispheres 42.4
2261 Male, age 18, unknown 40.2
2668 Female, age 75, unknown 40.2
1839 Male, age 51, unknown 40.0
1913 Female, age 42, unknown 39.5
1796 Male, age 53, unknown 39.0
1895 Male, age 76, right hemisphere 38.9
1995 Male, age 72, unknown 38.9
2587 Male, age 74, left hemisphere 38.7
2087 Female, age 72, unknown 34.7
Ventral tegmental area
nTPM: 40.0
1942 Male, age 51, unknown 44.3
1915 Female, age 42, unknown 41.6
2021 Male, age 53, unknown 41.4
2218 Male, age 76, both hemispheres 39.3
2223 Female, age 72, unknown 37.0
2410 Female, age 72, unknown 36.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 38.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 38.5
Samples: 139

Max nTPM: 65.8
Min nTPM: 21.7
Std nTPM: 7.0
Median nTPM: 37.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 65.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 54.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 54.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 54.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 53.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 52.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 52.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 52.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 51.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 50.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 50.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 49.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 49.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 49.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 48.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 47.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 47.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 46.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 46.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 46.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 46.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 46.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 45.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 44.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 44.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 44.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 43.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 43.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 43.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 43.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 42.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 42.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 42.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 42.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 41.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 41.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 41.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 41.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 41.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 40.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 40.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 40.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 40.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 40.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 40.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 39.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 39.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 39.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 39.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 39.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 39.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 39.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 39.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 38.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 38.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 38.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 38.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 38.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 38.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 38.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 38.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 38.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 37.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 37.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 37.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 37.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 37.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 37.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 37.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 36.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 36.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 36.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 36.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 36.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 36.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 36.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 36.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 36.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 36.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 36.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 35.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 35.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 35.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 35.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 35.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 35.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 35.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 35.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 35.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 34.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 34.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 34.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 34.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 34.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 34.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 34.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 34.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 34.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 34.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 34.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 33.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 33.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 33.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 33.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 33.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 33.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 33.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 33.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 33.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 33.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 33.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 32.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 32.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 32.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 32.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 32.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 32.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 32.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 32.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 32.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 31.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 31.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 31.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 31.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 30.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 30.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 30.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 29.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 29.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 28.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 28.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 28.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 27.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 27.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 25.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 24.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 21.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 32.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 32.1
FF:10158-103A5 76 years, female 32.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 29.0
Pig sample Sample description nTPM
Midbrain
nTPM: 26.7
Samples: 4

Max nTPM: 32.4
Min nTPM: 20.4
Sample A Female 20.4
Sample B Female 24.2
Sample C Male 32.4
Sample D Male 29.7
Periaqueductal gray
nTPM: 25.1
Samples: 3

Max nTPM: 31.3
Min nTPM: 21.7
Sample B Female 22.4
Sample C Male 31.3
Sample D Male 21.7
Substantia nigra
nTPM: 26.6
Samples: 4

Max nTPM: 32.9
Min nTPM: 18.5
Sample A Female 32.9
Sample B Female 23.4
Sample C Male 31.6
Sample D Male 18.5
Superior colliculi
nTPM: 29.0
Samples: 4

Max nTPM: 33.1
Min nTPM: 25.3
Sample A Female 33.1
Sample B Female 25.3
Sample C Male 29.2
Sample D Male 28.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 43.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 43.2
Samples: 4

Max nTPM: 46.2
Min nTPM: 39.5
Sample A Male 46.2
Sample B Male 43.0
Sample C Female 39.5
Sample D Female 44.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.2
293258 Antisense, RP_040617_01_A05, Mouse strain C57BL/6J (56 days, male) 8.7
81599610 Antisense, RP_071126_01_B08, Mouse strain C57BL/6J (56 days, male) 5.6

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