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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:141.6 nTPM
HPA:141.6 nTPM
GTEx:207.2 nTPM
FANTOM5:255.2 Scaled Tags Per Million
Pig:83.1 nTPM
Mouse:160.2 nTPM
Allen mouse:1.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 141.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 124.0
2411 Female, age 72, unknown 146.8
2828 Female, age 72, unknown 138.8
1870 Female, age 42, unknown 132.3
1833 Male, age 53, unknown 125.4
2219 Male, age 76, both hemispheres 120.7
2019 Male, age 18, unknown 120.0
1830 Male, age 51, unknown 118.0
1827 Male, age 72, unknown 116.9
2666 Male, age 74, left hemisphere 111.3
2586 Male, age 75, left hemisphere 110.0
Dorsal raphe nucleus
nTPM: 141.6
2298 Female, age 72, unknown 155.5
2047 Male, age 72, unknown 142.3
2750 Male, age 76, both hemispheres 140.7
2016 Female, age 72, unknown 135.5
1828 Male, age 53, unknown 134.2
Inferior colliculus
nTPM: 129.1
2097 Female, age 72, unknown 140.0
1890 Male, age 53, unknown 131.7
1848 Female, age 42, unknown 128.9
2849 Male, age 72, unknown 115.9
Median raphe nucleus
nTPM: 127.0
2220 Male, age 76, midline 127.0
Pedunculopontine tegmental nucleus
nTPM: 129.8
1921 Female, age 85, both hemispheres 135.0
2334 Male, age 80, both hemispheres 134.6
2338 Male, age 61, both hemispheres 119.9
Periaquaductal grey, anterior
nTPM: 114.9
1947 Male, age 18, unknown 118.7
1795 Male, age 51, unknown 115.2
2502 Female, age 75, unknown 110.8
Periaquaductal grey, dorsal
nTPM: 123.2
2464 Female, age 72, unknown 136.3
1840 Male, age 53, unknown 123.1
2850 Male, age 76, both hemispheres 118.7
1831 Male, age 72, unknown 114.7
Periaquaductal grey, lateral
nTPM: 119.9
2053 Male, age 18, unknown 124.8
2272 Male, age 74, both hemispheres 119.7
2140 Male, age 76, both hemispheres 115.1
Pretectal area
nTPM: 121.7
2667 Female, age 75, unknown 134.2
1817 Female, age 42, unknown 129.8
2224 Female, age 72, unknown 127.8
1944 Female, age 72, unknown 125.9
2273 Male, age 74, both hemispheres 125.3
1815 Male, age 53, unknown 124.7
2825 Male, age 18, unknown 122.2
2316 Male, age 76, right hemisphere 117.0
1816 Male, age 51, unknown 116.8
2007 Male, age 72, unknown 112.5
2407 Male, age 75, both hemispheres 102.5
Red nucleus
nTPM: 133.6
1821 Female, age 72, unknown 150.5
2503 Female, age 72, unknown 148.5
1954 Female, age 42, unknown 143.1
2769 Male, age 72, unknown 139.0
1904 Male, age 53, unknown 138.2
2227 Male, age 72, unknown 138.0
2823 Male, age 76, right hemisphere 135.8
1865 Male, age 51, unknown 135.0
2725 Female, age 75, unknown 131.8
2785 Male, age 18, unknown 117.8
2588 Male, age 74, left hemisphere 116.3
2584 Male, age 75, left hemisphere 108.7
Substantia nigra
nTPM: 132.9
2241 Male, age 72, unknown 147.9
2699 Male, age 18, unknown 144.1
1916 Female, age 42, unknown 140.5
1851 Male, age 51, unknown 139.8
2409 Female, age 72, unknown 136.9
1889 Female, age 72, unknown 131.4
1941 Male, age 53, unknown 125.9
2590 Female, age 75, unknown 124.6
2665 Male, age 74, both hemispheres 123.6
2583 Male, age 75, right hemisphere 114.3
Superior colliculus
nTPM: 119.3
1995 Male, age 72, unknown 133.6
1913 Female, age 42, unknown 127.6
2087 Female, age 72, unknown 127.1
1796 Male, age 53, unknown 118.5
2587 Male, age 74, left hemisphere 118.5
2668 Female, age 75, unknown 118.1
1839 Male, age 51, unknown 118.0
1895 Male, age 76, right hemisphere 117.0
2261 Male, age 18, unknown 115.3
2664 Male, age 75, both hemispheres 99.0
Ventral tegmental area
nTPM: 132.4
2410 Female, age 72, unknown 142.3
1942 Male, age 51, unknown 133.4
1915 Female, age 42, unknown 132.9
2223 Female, age 72, unknown 130.9
2021 Male, age 53, unknown 128.2
2218 Male, age 76, both hemispheres 127.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 207.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 207.2
Samples: 139

Max nTPM: 459.5
Min nTPM: 60.0
Std nTPM: 75.0
Median nTPM: 193.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 459.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 416.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 409.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 401.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 373.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 367.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 365.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 363.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 359.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 335.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 332.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 327.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 317.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 307.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 303.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 298.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 294.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 292.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 282.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 278.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 276.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 269.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 268.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 267.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 267.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 264.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 261.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 260.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 257.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 256.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 255.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 255.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 251.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 250.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 248.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 246.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 246.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 245.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 243.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 242.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 241.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 240.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 239.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 233.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 232.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 228.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 227.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 226.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 226.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 224.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 224.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 221.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 221.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 220.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 215.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 215.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 214.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 210.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 210.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 209.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 208.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 208.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 207.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 206.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 205.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 199.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 198.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 198.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 196.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 193.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 191.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 191.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 190.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 190.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 188.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 187.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 186.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 185.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 182.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 182.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 181.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 181.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 180.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 177.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 174.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 173.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 173.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 171.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 171.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 171.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 170.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 168.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 168.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 165.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 165.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 165.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 165.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 164.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 159.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 159.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 157.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 157.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 156.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 156.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 155.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 153.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 152.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 151.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 149.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 145.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 144.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 144.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 141.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 140.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 140.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 140.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 138.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 137.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 136.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 136.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 135.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 133.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 128.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 127.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 123.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 123.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 120.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 120.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 118.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 114.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 108.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 101.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 94.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 92.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 92.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 92.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 90.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 84.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 60.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 255.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 255.2
FF:10158-103A5 76 years, female 255.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 83.1
Pig sample Sample description nTPM
Midbrain
nTPM: 83.1
Samples: 4

Max nTPM: 112.8
Min nTPM: 59.6
Sample A Female 112.8
Sample B Female 90.3
Sample C Male 69.7
Sample D Male 59.6
Periaqueductal gray
nTPM: 73.3
Samples: 3

Max nTPM: 84.4
Min nTPM: 63.7
Sample B Female 84.4
Sample C Male 71.9
Sample D Male 63.7
Substantia nigra
nTPM: 81.7
Samples: 4

Max nTPM: 90.0
Min nTPM: 76.2
Sample A Female 90.0
Sample B Female 77.6
Sample C Male 76.2
Sample D Male 83.0
Superior colliculi
nTPM: 72.2
Samples: 4

Max nTPM: 82.0
Min nTPM: 63.8
Sample A Female 82.0
Sample B Female 63.8
Sample C Male 75.3
Sample D Male 67.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 160.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 160.1
Samples: 4

Max nTPM: 165.3
Min nTPM: 150.1
Sample A Male 165.3
Sample B Male 162.0
Sample C Female 150.1
Sample D Female 163.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.4
76115729 Antisense, RP_060620_02_B08, Mouse strain C57BL/6J (56 days, male) 1.5
71381040 Antisense, RP_050503_01_F02, Mouse strain C57BL/6J (56 days, male) 1.3

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