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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 28.5
Min nTPM: 11.8
Std nTPM: 3.1
Median nTPM:
495_1
57 years, female
28.5
413_1
59 years, female
26.9
217_1
76 years, male
24.4
466_1
57 years, female
24.4
491_1
89 years, female
24.3
308_1
70 years, female
23.6
490_1
67 years, female
22.8
307_1
66 years, female
22.5
149_1
88 years, male
22.2
414_1
84 years, female
21.9
468_1
89 years, male
21.6
415_1
77 years, female
21.3
265_1
87 years, male
21.2
153_1
70 years, female
21.1
126_1
63 years, male
20.9
324_1
76 years, male
20.7
311_1
78 years, male
20.1
142_1
61 years, female
19.8
32_1
67 years, male
19.7
120_1
70 years, female
19.6
89_1
63 years, male
19.5
41_1
94 years, female
19.4
117_1
61 years, male
19.3
9_1
66 years, female
19.2
119_1
70 years, female
19.1
447_1
81 years, male
19.1
43_1
64 years, female
19.0
139_1
64 years, female
19.0
317_1
60 years, male
19.0
162_1
79 years, female
18.7
99_1
64 years, male
18.6
315_1
62 years, female
18.6
229_1
69 years, female
18.5
518_1
75 years, female
18.5
501_1
88 years, male
18.3
145_1
84 years, male
17.8
384_1
83 years, male
17.7
173_1
67 years, male
17.5
313_1
79 years, female
17.5
6_1
73 years, female
17.3
266_1
85 years, male
17.3
379_1
60 years, male
17.3
17_1
71 years, male
17.2
81_1
67 years, male
17.2
499_1
55 years, female
17.2
189_1
76 years, male
17.1
18_1
88 years, male
17.0
526_1
61 years, male
17.0
394_1
75 years, female
16.9
254_1
77 years, female
16.8
42_1
85 years, male
16.7
137_1
83 years, male
16.7
405_1
91 years, male
16.7
35_1
74 years, female
16.6
386_1
76 years, male
16.6
389_1
86 years, female
16.6
115_1
83 years, male
16.5
246_1
77 years, male
16.5
404_1
82 years, female
16.3
314_1
67 years, male
16.2
288_1
66 years, female
16.0
396_1
62 years, male
16.0
2_1
77 years, female
15.9
321_1
62 years, female
15.9
375_1
74 years, female
15.9
348_1
84 years, male
15.8
109_1
81 years, female
15.7
452_1
88 years, female
15.7
4_1
88 years, female
15.6
335_1
73 years, female
15.6
425_1
59 years, female
15.6
293_1
68 years, female
15.5
177_1
74 years, male
15.3
318_1
68 years, male
15.3
355_1
70 years, female
15.3
517_1
88 years, male
15.3
291_1
76 years, male
15.2
322_1
76 years, male
15.2
347_1
72 years, male
15.2
356_1
87 years, female
15.2
264_1
73 years, female
15.1
295_1
61 years, female
15.0
480_1
63 years, male
15.0
377_1
82 years, female
14.9
218_1
71 years, female
14.7
237_1
82 years, male
14.7
506_1
65 years, male
14.7
251_1
78 years, male
14.6
320_1
89 years, female
14.2
243_1
75 years, male
13.8
349_1
83 years, male
13.8
351_1
91 years, male
13.8
376_1
75 years, female
13.8
286_1
68 years, female
13.7
406_1
79 years, male
13.6
503_1
68 years, male
13.6
316_1
62 years, male
13.5
172_1
72 years, female
13.4
350_1
84 years, female
13.4
352_1
62 years, male
12.8
319_1
81 years, male
12.7
353_1
82 years, female
12.7
292_1
71 years, male
12.2
354_1
81 years, female
12.2
163_1
78 years, male
11.8
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
