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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:85.6 nTPM
HPA:85.6 nTPM
GTEx:85.3 nTPM
FANTOM5:89.7 Scaled Tags Per Million
Pig:86.9 nTPM
Mouse:165.4 nTPM
Allen mouse:7.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 85.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 77.8
1870 Female, age 42, unknown 83.2
2411 Female, age 72, unknown 81.5
1833 Male, age 53, unknown 80.0
2019 Male, age 18, unknown 79.6
2828 Female, age 72, unknown 79.0
1827 Male, age 72, unknown 77.9
1830 Male, age 51, unknown 77.9
2219 Male, age 76, both hemispheres 75.7
2586 Male, age 75, left hemisphere 72.0
2666 Male, age 74, left hemisphere 71.2
Dorsal raphe nucleus
nTPM: 85.0
2298 Female, age 72, unknown 93.9
2016 Female, age 72, unknown 84.1
1828 Male, age 53, unknown 83.3
2047 Male, age 72, unknown 82.0
2750 Male, age 76, both hemispheres 81.6
Inferior colliculus
nTPM: 81.0
2097 Female, age 72, unknown 85.5
1848 Female, age 42, unknown 80.7
1890 Male, age 53, unknown 79.9
2849 Male, age 72, unknown 77.9
Median raphe nucleus
nTPM: 79.8
2220 Male, age 76, midline 79.8
Pedunculopontine tegmental nucleus
nTPM: 82.0
2338 Male, age 61, both hemispheres 83.2
2334 Male, age 80, both hemispheres 81.6
1921 Female, age 85, both hemispheres 81.1
Periaquaductal grey, anterior
nTPM: 79.7
2502 Female, age 75, unknown 80.6
1947 Male, age 18, unknown 80.0
1795 Male, age 51, unknown 78.5
Periaquaductal grey, dorsal
nTPM: 82.3
1840 Male, age 53, unknown 84.8
2850 Male, age 76, both hemispheres 82.8
1831 Male, age 72, unknown 81.2
2464 Female, age 72, unknown 80.5
Periaquaductal grey, lateral
nTPM: 85.6
2272 Male, age 74, both hemispheres 91.7
2053 Male, age 18, unknown 84.1
2140 Male, age 76, both hemispheres 81.0
Pretectal area
nTPM: 81.5
2273 Male, age 74, both hemispheres 96.8
2224 Female, age 72, unknown 85.9
2667 Female, age 75, unknown 82.3
1944 Female, age 72, unknown 80.6
1816 Male, age 51, unknown 80.3
2316 Male, age 76, right hemisphere 80.3
2825 Male, age 18, unknown 79.4
1817 Female, age 42, unknown 78.5
1815 Male, age 53, unknown 78.0
2407 Male, age 75, both hemispheres 77.6
2007 Male, age 72, unknown 76.7
Red nucleus
nTPM: 79.5
1821 Female, age 72, unknown 86.3
2823 Male, age 76, right hemisphere 81.6
2725 Female, age 75, unknown 81.5
1865 Male, age 51, unknown 80.4
2503 Female, age 72, unknown 80.4
1954 Female, age 42, unknown 80.3
2769 Male, age 72, unknown 80.2
2227 Male, age 72, unknown 79.5
1904 Male, age 53, unknown 79.2
2785 Male, age 18, unknown 78.5
2584 Male, age 75, left hemisphere 73.9
2588 Male, age 74, left hemisphere 72.7
Substantia nigra
nTPM: 81.0
2241 Male, age 72, unknown 86.6
1851 Male, age 51, unknown 83.2
2409 Female, age 72, unknown 81.8
2699 Male, age 18, unknown 81.7
1916 Female, age 42, unknown 81.5
1889 Female, age 72, unknown 80.9
1941 Male, age 53, unknown 80.8
2590 Female, age 75, unknown 80.3
2665 Male, age 74, both hemispheres 77.1
2583 Male, age 75, right hemisphere 75.7
Superior colliculus
nTPM: 80.2
2587 Male, age 74, left hemisphere 86.1
1995 Male, age 72, unknown 84.4
1913 Female, age 42, unknown 83.0
2261 Male, age 18, unknown 79.8
1796 Male, age 53, unknown 79.7
2087 Female, age 72, unknown 79.0
1895 Male, age 76, right hemisphere 78.8
1839 Male, age 51, unknown 78.6
2668 Female, age 75, unknown 76.4
2664 Male, age 75, both hemispheres 76.0
Ventral tegmental area
nTPM: 81.6
2223 Female, age 72, unknown 82.3
2410 Female, age 72, unknown 82.3
2021 Male, age 53, unknown 82.2
1915 Female, age 42, unknown 82.0
1942 Male, age 51, unknown 80.9
2218 Male, age 76, both hemispheres 80.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 85.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 85.3
Samples: 139

Max nTPM: 166.0
Min nTPM: 50.9
Std nTPM: 21.1
Median nTPM: 80.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 166.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 158.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 151.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 142.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 139.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 138.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 129.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 121.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 120.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 118.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 116.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 111.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 111.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 109.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 108.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 107.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 107.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 107.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 106.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 106.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 105.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 105.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 104.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 104.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 103.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 103.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 102.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 102.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 101.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 101.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 101.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 101.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 100.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 100.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 98.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 98.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 96.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 94.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 93.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 92.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 92.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 90.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 90.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 90.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 90.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 89.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 89.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 87.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 86.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 86.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 85.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 84.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 84.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 84.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 84.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 83.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 83.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 83.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 82.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 82.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 82.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 81.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 81.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 81.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 81.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 81.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 81.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 80.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 80.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 80.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 80.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 79.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 79.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 79.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 79.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 78.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 77.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 77.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 77.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 77.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 76.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 75.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 74.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 74.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 74.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 74.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 74.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 74.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 73.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 73.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 73.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 72.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 72.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 72.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 72.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 72.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 71.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 71.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 71.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 71.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 71.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 70.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 70.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 70.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 69.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 69.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 69.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 69.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 69.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 69.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 69.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 68.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 68.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 67.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 67.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 67.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 66.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 66.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 66.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 65.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 65.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 65.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 64.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 64.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 63.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 63.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 61.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 61.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 60.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 60.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 60.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 58.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 58.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 57.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 55.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 53.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 50.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 89.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 89.7
FF:10158-103A5 76 years, female 89.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 86.9
Pig sample Sample description nTPM
Midbrain
nTPM: 80.8
Samples: 4

Max nTPM: 90.3
Min nTPM: 73.5
Sample A Female 73.5
Sample B Female 90.3
Sample C Male 83.2
Sample D Male 76.2
Periaqueductal gray
nTPM: 64.4
Samples: 3

Max nTPM: 68.1
Min nTPM: 59.4
Sample B Female 65.7
Sample C Male 68.1
Sample D Male 59.4
Substantia nigra
nTPM: 80.1
Samples: 4

Max nTPM: 113.3
Min nTPM: 42.7
Sample A Female 113.3
Sample B Female 82.7
Sample C Male 81.7
Sample D Male 42.7
Superior colliculi
nTPM: 86.9
Samples: 4

Max nTPM: 99.5
Min nTPM: 74.5
Sample A Female 99.5
Sample B Female 78.4
Sample C Male 95.1
Sample D Male 74.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 165.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 165.4
Samples: 4

Max nTPM: 176.3
Min nTPM: 148.6
Sample A Male 164.7
Sample B Male 176.3
Sample C Female 148.6
Sample D Female 172.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.9
69672144 Antisense, RP_050428_03_B03, Mouse strain C57BL/6J (56 days, male) 7.9

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