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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA000261
Distinct cytoplasmic positivity of myoepitelial and smooth muscle cells was observed.
HPA009066
Strong cytoplasmic immunoreactivity was observed in myocytes and megakaryocytes in bone marrow. Luminal membranes were positive in gastrointestinal tract. Remaining normal tissues were weakly stained or negative.
HPA047089
Most normal tissues displayed moderate to strong cytoplasmic positivity. Soft tissues were weakly stained or negative.
HPA053624
Normal tissues displayed moderate to strong nuclear staining with additional cytoplasmic and/or membranous positivity in several tissues. Liver, pneumocytes, lymph node, exocrine pancreas and prostate were weakly stained or negative.
CAB017698
Strong cytoplasmic positivity was observed in heart and skeletal muscle while cytoplasmic and membranous staining was observed in stomach and gall bladder. Cells in CNS, squamous epithelia, mesenchymal cells and liver were negative. Most remaining tissues displayed weak to moderate cytoplasmic and membranous staining.