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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA030226
Normal tissues displayed weak to moderate cytoplasmic and nuclear/ nucleolar positivity with additional membranous staining in gastrointestinal tract, respiratory epithelia and prostate. Purkinje cells, trophoblastic cells, skeletal muscle cells, stomach and squamous epithelia were strongly positive. Bile duct cells were negative.
HPA030227
Most of the normal tissues showed moderate to strong membranous, nucleolar and cytoplasmic positivity. The glial cells and most lymphoid cells were negative or weakly stained.
HPA030228
Most normal tissues displayed moderate nuclear positivity with additional cytoplasmic immunoreactivity in many cases. Stomach, adrenal cortex, prostate, neuronal cells and skeletal myocytes were strongly stained. The liver and lymphoid cells were weakly stained or negative.
The Human Protein Atlas project is funded
