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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:69.5 nTPM
HPA:69.5 nTPM
GTEx:55.6 nTPM
FANTOM5:168.6 Scaled Tags Per Million
Pig:54.3 nTPM
Mouse:340.5 nTPM
Allen mouse:12.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 69.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 60.3
2019 Male, age 18, unknown 80.4
2411 Female, age 72, unknown 69.6
1827 Male, age 72, unknown 63.1
2219 Male, age 76, both hemispheres 61.3
1833 Male, age 53, unknown 60.1
2828 Female, age 72, unknown 58.1
1830 Male, age 51, unknown 57.7
1870 Female, age 42, unknown 55.8
2666 Male, age 74, left hemisphere 50.9
2586 Male, age 75, left hemisphere 46.1
Dorsal raphe nucleus
nTPM: 59.8
1828 Male, age 53, unknown 66.6
2298 Female, age 72, unknown 63.0
2750 Male, age 76, both hemispheres 59.1
2047 Male, age 72, unknown 56.5
2016 Female, age 72, unknown 53.7
Inferior colliculus
nTPM: 62.9
2097 Female, age 72, unknown 68.2
1848 Female, age 42, unknown 64.9
1890 Male, age 53, unknown 61.5
2849 Male, age 72, unknown 57.2
Median raphe nucleus
nTPM: 55.6
2220 Male, age 76, midline 55.6
Pedunculopontine tegmental nucleus
nTPM: 62.8
1921 Female, age 85, both hemispheres 66.8
2334 Male, age 80, both hemispheres 62.4
2338 Male, age 61, both hemispheres 59.3
Periaquaductal grey, anterior
nTPM: 56.1
1947 Male, age 18, unknown 58.3
1795 Male, age 51, unknown 57.1
2502 Female, age 75, unknown 52.8
Periaquaductal grey, dorsal
nTPM: 54.8
2464 Female, age 72, unknown 58.0
2850 Male, age 76, both hemispheres 55.7
1840 Male, age 53, unknown 54.2
1831 Male, age 72, unknown 51.3
Periaquaductal grey, lateral
nTPM: 56.5
2272 Male, age 74, both hemispheres 67.7
2053 Male, age 18, unknown 52.4
2140 Male, age 76, both hemispheres 49.4
Pretectal area
nTPM: 68.3
2007 Male, age 72, unknown 81.9
1817 Female, age 42, unknown 79.7
1816 Male, age 51, unknown 79.0
2667 Female, age 75, unknown 77.2
1944 Female, age 72, unknown 74.0
1815 Male, age 53, unknown 70.7
2273 Male, age 74, both hemispheres 65.1
2224 Female, age 72, unknown 60.7
2316 Male, age 76, right hemisphere 59.8
2407 Male, age 75, both hemispheres 54.2
2825 Male, age 18, unknown 48.7
Red nucleus
nTPM: 62.5
1821 Female, age 72, unknown 70.7
2785 Male, age 18, unknown 69.8
2823 Male, age 76, right hemisphere 66.6
2503 Female, age 72, unknown 65.4
2725 Female, age 75, unknown 64.0
1904 Male, age 53, unknown 61.6
2227 Male, age 72, unknown 60.2
1865 Male, age 51, unknown 59.5
1954 Female, age 42, unknown 59.4
2769 Male, age 72, unknown 59.4
2588 Male, age 74, left hemisphere 59.1
2584 Male, age 75, left hemisphere 53.7
Substantia nigra
nTPM: 69.5
1916 Female, age 42, unknown 79.6
2241 Male, age 72, unknown 79.2
1889 Female, age 72, unknown 78.5
2409 Female, age 72, unknown 72.3
1851 Male, age 51, unknown 71.7
1941 Male, age 53, unknown 68.0
2590 Female, age 75, unknown 63.4
2699 Male, age 18, unknown 61.6
2665 Male, age 74, both hemispheres 61.4
2583 Male, age 75, right hemisphere 58.9
Superior colliculus
nTPM: 60.1
2087 Female, age 72, unknown 71.7
1895 Male, age 76, right hemisphere 70.1
2587 Male, age 74, left hemisphere 64.3
2261 Male, age 18, unknown 62.8
1796 Male, age 53, unknown 62.3
2668 Female, age 75, unknown 58.5
1839 Male, age 51, unknown 56.8
1995 Male, age 72, unknown 54.3
1913 Female, age 42, unknown 53.3
2664 Male, age 75, both hemispheres 46.7
Ventral tegmental area
nTPM: 61.0
2410 Female, age 72, unknown 72.8
2218 Male, age 76, both hemispheres 67.3
1915 Female, age 42, unknown 64.9
1942 Male, age 51, unknown 55.4
2223 Female, age 72, unknown 53.7
2021 Male, age 53, unknown 51.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 55.6
Samples: 139

Max nTPM: 106.8
Min nTPM: 28.9
Std nTPM: 14.5
Median nTPM: 53.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 106.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 105.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 84.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 83.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 81.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 77.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 77.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 76.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 76.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 76.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 75.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 74.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 74.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 74.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 74.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 74.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 72.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 71.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 70.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 70.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 70.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 69.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 69.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 69.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 69.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 66.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 66.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 65.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 65.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 65.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 64.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 62.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 62.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 62.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 62.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 62.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 61.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 61.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 61.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 61.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 61.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 61.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 61.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 60.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 60.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 60.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 60.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 60.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 59.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 59.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 58.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 58.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 58.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 57.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 57.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 56.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 55.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 55.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 55.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 55.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 55.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 55.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 54.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 54.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 54.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 54.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 53.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 53.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 53.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 53.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 53.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 52.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 52.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 52.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 52.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 52.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 51.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 51.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 51.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 50.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 50.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 50.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 50.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 50.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 49.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 49.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 49.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 48.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 48.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 48.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 48.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 48.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 47.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 47.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 46.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 46.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 46.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 46.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 46.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 45.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 45.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 45.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 44.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 44.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 43.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 42.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 42.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 42.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 42.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 42.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 42.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 42.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 41.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 39.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 39.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 39.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 39.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 38.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 38.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 38.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 37.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 37.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 37.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 36.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 35.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 34.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 34.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 34.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 32.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 31.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 29.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 28.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 168.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 168.6
FF:10158-103A5 76 years, female 168.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.3
Pig sample Sample description nTPM
Midbrain
nTPM: 48.1
Samples: 4

Max nTPM: 61.3
Min nTPM: 39.3
Sample A Female 39.3
Sample B Female 44.4
Sample C Male 61.3
Sample D Male 47.3
Periaqueductal gray
nTPM: 37.2
Samples: 3

Max nTPM: 40.3
Min nTPM: 32.5
Sample B Female 40.3
Sample C Male 38.9
Sample D Male 32.5
Substantia nigra
nTPM: 43.5
Samples: 4

Max nTPM: 54.2
Min nTPM: 33.8
Sample A Female 54.2
Sample B Female 38.3
Sample C Male 47.5
Sample D Male 33.8
Superior colliculi
nTPM: 54.3
Samples: 4

Max nTPM: 69.1
Min nTPM: 45.8
Sample A Female 56.2
Sample B Female 45.8
Sample C Male 69.1
Sample D Male 46.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 340.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 340.5
Samples: 4

Max nTPM: 346.3
Min nTPM: 327.7
Sample A Male 344.2
Sample B Male 346.3
Sample C Female 327.7
Sample D Female 343.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.3
655502 Antisense, RP_040922_01_C03, Mouse strain C57BL/6J (56 days, male) 13.6
72723 Antisense, RP_040407_01_A05, Mouse strain C57BL/6J (56 days, male) 11.0

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