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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 172.7
Min nTPM: 29.4
Std nTPM: 24.6
Median nTPM:
352_1
62 years, male
172.7
218_1
71 years, female
147.0
356_1
87 years, female
136.2
316_1
62 years, male
132.9
319_1
81 years, male
130.0
163_1
78 years, male
126.0
354_1
81 years, female
124.3
350_1
84 years, female
124.1
322_1
76 years, male
115.3
172_1
72 years, female
114.2
286_1
68 years, female
113.3
321_1
62 years, female
111.2
503_1
68 years, male
109.1
2_1
77 years, female
107.1
351_1
91 years, male
106.7
406_1
79 years, male
105.5
295_1
61 years, female
104.6
447_1
81 years, male
104.4
355_1
70 years, female
103.3
377_1
82 years, female
103.2
237_1
82 years, male
101.6
318_1
68 years, male
101.5
320_1
89 years, female
100.2
353_1
82 years, female
98.8
335_1
73 years, female
98.6
349_1
83 years, male
98.0
348_1
84 years, male
97.4
480_1
63 years, male
96.6
6_1
73 years, female
96.2
293_1
68 years, female
95.9
243_1
75 years, male
94.1
394_1
75 years, female
93.9
425_1
59 years, female
93.9
376_1
75 years, female
93.7
229_1
69 years, female
91.5
292_1
71 years, male
90.7
217_1
76 years, male
90.4
291_1
76 years, male
89.1
379_1
60 years, male
88.5
386_1
76 years, male
87.4
251_1
78 years, male
87.3
384_1
83 years, male
86.7
517_1
88 years, male
85.2
495_1
57 years, female
84.8
452_1
88 years, female
84.2
177_1
74 years, male
83.9
311_1
78 years, male
83.1
526_1
61 years, male
82.4
404_1
82 years, female
81.4
405_1
91 years, male
81.3
307_1
66 years, female
80.5
396_1
62 years, male
79.9
375_1
74 years, female
79.6
264_1
73 years, female
79.5
518_1
75 years, female
79.3
43_1
64 years, female
78.4
347_1
72 years, male
77.8
468_1
89 years, male
77.5
317_1
60 years, male
76.1
389_1
86 years, female
75.3
189_1
76 years, male
75.1
99_1
64 years, male
74.3
313_1
79 years, female
73.6
35_1
74 years, female
73.5
9_1
66 years, female
73.2
81_1
67 years, male
72.8
265_1
87 years, male
72.0
173_1
67 years, male
71.5
499_1
55 years, female
71.4
466_1
57 years, female
70.8
506_1
65 years, male
70.7
266_1
85 years, male
70.5
246_1
77 years, male
69.8
126_1
63 years, male
68.6
115_1
83 years, male
68.3
32_1
67 years, male
67.5
288_1
66 years, female
67.3
142_1
61 years, female
67.2
153_1
70 years, female
65.8
314_1
67 years, male
65.8
324_1
76 years, male
63.9
137_1
83 years, male
63.5
414_1
84 years, female
63.5
18_1
88 years, male
62.8
139_1
64 years, female
59.2
117_1
61 years, male
57.9
254_1
77 years, female
57.7
501_1
88 years, male
56.1
162_1
79 years, female
55.9
4_1
88 years, female
55.1
491_1
89 years, female
53.0
109_1
81 years, female
52.0
149_1
88 years, male
51.6
145_1
84 years, male
51.5
120_1
70 years, female
50.7
308_1
70 years, female
50.5
415_1
77 years, female
50.4
413_1
59 years, female
50.3
89_1
63 years, male
49.5
42_1
85 years, male
48.7
17_1
71 years, male
48.0
490_1
67 years, female
47.3
315_1
62 years, female
44.4
41_1
94 years, female
42.5
119_1
70 years, female
29.4
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
