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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:34.9 nTPM
HPA:34.9 nTPM
GTEx:49.9 nTPM
FANTOM5:50.4 Scaled Tags Per Million
Pig:11.5 nTPM
Mouse:30.7 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 34.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 34.3
1870 Female, age 42, unknown 35.8
2411 Female, age 72, unknown 35.8
2828 Female, age 72, unknown 34.9
1827 Male, age 72, unknown 34.5
1830 Male, age 51, unknown 34.3
2019 Male, age 18, unknown 34.3
2219 Male, age 76, both hemispheres 33.8
2666 Male, age 74, left hemisphere 33.8
1833 Male, age 53, unknown 33.7
2586 Male, age 75, left hemisphere 32.7
Dorsal raphe nucleus
nTPM: 33.3
2750 Male, age 76, both hemispheres 34.5
2298 Female, age 72, unknown 34.3
1828 Male, age 53, unknown 33.3
2047 Male, age 72, unknown 32.5
2016 Female, age 72, unknown 32.0
Inferior colliculus
nTPM: 32.7
2097 Female, age 72, unknown 34.3
2849 Male, age 72, unknown 33.7
1848 Female, age 42, unknown 32.4
1890 Male, age 53, unknown 30.6
Median raphe nucleus
nTPM: 33.8
2220 Male, age 76, midline 33.8
Pedunculopontine tegmental nucleus
nTPM: 32.8
2334 Male, age 80, both hemispheres 34.8
1921 Female, age 85, both hemispheres 32.4
2338 Male, age 61, both hemispheres 31.4
Periaquaductal grey, anterior
nTPM: 33.5
2502 Female, age 75, unknown 34.6
1947 Male, age 18, unknown 33.3
1795 Male, age 51, unknown 32.5
Periaquaductal grey, dorsal
nTPM: 31.6
1840 Male, age 53, unknown 33.3
2464 Female, age 72, unknown 32.1
1831 Male, age 72, unknown 31.1
2850 Male, age 76, both hemispheres 29.9
Periaquaductal grey, lateral
nTPM: 31.3
2272 Male, age 74, both hemispheres 33.3
2053 Male, age 18, unknown 30.3
2140 Male, age 76, both hemispheres 30.2
Pretectal area
nTPM: 32.8
1817 Female, age 42, unknown 35.2
2007 Male, age 72, unknown 34.5
1944 Female, age 72, unknown 34.4
1816 Male, age 51, unknown 33.9
2224 Female, age 72, unknown 33.6
1815 Male, age 53, unknown 33.3
2316 Male, age 76, right hemisphere 32.1
2273 Male, age 74, both hemispheres 31.6
2667 Female, age 75, unknown 31.4
2825 Male, age 18, unknown 31.1
2407 Male, age 75, both hemispheres 29.5
Red nucleus
nTPM: 34.9
2503 Female, age 72, unknown 37.6
2769 Male, age 72, unknown 36.5
1821 Female, age 72, unknown 36.2
2227 Male, age 72, unknown 35.8
1904 Male, age 53, unknown 35.7
2785 Male, age 18, unknown 34.9
2725 Female, age 75, unknown 34.8
1865 Male, age 51, unknown 34.6
2823 Male, age 76, right hemisphere 34.2
2588 Male, age 74, left hemisphere 33.5
2584 Male, age 75, left hemisphere 32.9
1954 Female, age 42, unknown 32.2
Substantia nigra
nTPM: 33.0
1916 Female, age 42, unknown 37.3
1851 Male, age 51, unknown 35.5
2699 Male, age 18, unknown 34.9
2665 Male, age 74, both hemispheres 34.7
1889 Female, age 72, unknown 33.7
1941 Male, age 53, unknown 33.2
2583 Male, age 75, right hemisphere 31.9
2590 Female, age 75, unknown 31.7
2409 Female, age 72, unknown 28.8
2241 Male, age 72, unknown 28.6
Superior colliculus
nTPM: 33.6
1913 Female, age 42, unknown 35.0
2668 Female, age 75, unknown 35.0
1796 Male, age 53, unknown 34.8
1995 Male, age 72, unknown 34.7
2261 Male, age 18, unknown 34.4
2587 Male, age 74, left hemisphere 34.0
1895 Male, age 76, right hemisphere 32.9
2664 Male, age 75, both hemispheres 32.4
1839 Male, age 51, unknown 32.2
2087 Female, age 72, unknown 30.8
Ventral tegmental area
nTPM: 34.0
2410 Female, age 72, unknown 37.8
1915 Female, age 42, unknown 34.6
2223 Female, age 72, unknown 33.6
2218 Male, age 76, both hemispheres 33.1
1942 Male, age 51, unknown 32.7
2021 Male, age 53, unknown 32.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 49.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 49.9
Samples: 139

Max nTPM: 114.5
Min nTPM: 20.1
Std nTPM: 11.9
Median nTPM: 48.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 114.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 93.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 83.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 82.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 74.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 72.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 70.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 70.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 68.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 66.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 66.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 66.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 64.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 64.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 63.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 62.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 62.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 61.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 61.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 61.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 60.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 59.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 58.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 58.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 57.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 56.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 56.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 56.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 55.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 55.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 55.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 55.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 55.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 54.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 54.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 54.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 54.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 54.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 53.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 53.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 53.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 53.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 52.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 52.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 52.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 52.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 51.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 51.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 50.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 50.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 50.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 50.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 49.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 49.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 49.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 49.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 49.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 49.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 49.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 49.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 49.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 48.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 48.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 48.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 48.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 48.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 48.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 48.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 48.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 48.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 47.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 47.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 47.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 47.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 47.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 46.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 46.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 46.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 46.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 45.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 45.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 45.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 45.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 45.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 44.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 44.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 44.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 44.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 44.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 44.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 44.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 44.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 44.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 44.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 43.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 43.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 43.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 43.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 43.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 43.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 42.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 42.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 42.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 42.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 41.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 41.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 41.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 41.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 41.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 41.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 40.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 40.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 40.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 39.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 39.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 39.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 39.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 39.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 38.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 38.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 38.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 38.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 38.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 38.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 37.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 37.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 37.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 36.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 36.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 34.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 33.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 31.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 24.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 20.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 50.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 50.4
FF:10158-103A5 76 years, female 50.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 11.5
Pig sample Sample description nTPM
Midbrain
nTPM: 11.0
Samples: 4

Max nTPM: 15.1
Min nTPM: 9.2
Sample A Female 15.1
Sample B Female 10.3
Sample C Male 9.4
Sample D Male 9.2
Periaqueductal gray
nTPM: 8.6
Samples: 3

Max nTPM: 9.0
Min nTPM: 8.0
Sample B Female 9.0
Sample C Male 8.8
Sample D Male 8.0
Substantia nigra
nTPM: 10.7
Samples: 4

Max nTPM: 11.8
Min nTPM: 9.2
Sample A Female 11.8
Sample B Female 9.2
Sample C Male 10.5
Sample D Male 11.3
Superior colliculi
nTPM: 11.5
Samples: 4

Max nTPM: 12.0
Min nTPM: 10.9
Sample A Female 12.0
Sample B Female 10.9
Sample C Male 11.9
Sample D Male 11.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 30.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 30.7
Samples: 4

Max nTPM: 34.5
Min nTPM: 27.2
Sample A Male 34.5
Sample B Male 27.2
Sample C Female 27.3
Sample D Female 33.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
69782324 Antisense, RP_050505_02_G04, Mouse strain C57BL/6J (56 days, male) 0.1

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