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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:188.0 nTPM
HPA:188.0 nTPM
GTEx:110.0 nTPM
FANTOM5:329.0 Scaled Tags Per Million
Pig:66.3 nTPM
Mouse:33.3 nTPM
Allen mouse:0.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 188.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 161.5
2828 Female, age 72, unknown 227.3
2586 Male, age 75, left hemisphere 198.1
1870 Female, age 42, unknown 169.2
2666 Male, age 74, left hemisphere 166.5
1833 Male, age 53, unknown 160.5
2411 Female, age 72, unknown 158.1
1830 Male, age 51, unknown 156.8
2019 Male, age 18, unknown 151.9
1827 Male, age 72, unknown 145.2
2219 Male, age 76, both hemispheres 81.4
Dorsal raphe nucleus
nTPM: 154.0
2016 Female, age 72, unknown 184.3
1828 Male, age 53, unknown 172.9
2047 Male, age 72, unknown 155.1
2298 Female, age 72, unknown 145.3
2750 Male, age 76, both hemispheres 112.4
Inferior colliculus
nTPM: 158.9
1848 Female, age 42, unknown 168.5
1890 Male, age 53, unknown 163.2
2849 Male, age 72, unknown 157.6
2097 Female, age 72, unknown 146.4
Median raphe nucleus
nTPM: 104.0
2220 Male, age 76, midline 104.0
Pedunculopontine tegmental nucleus
nTPM: 118.5
2338 Male, age 61, both hemispheres 122.3
1921 Female, age 85, both hemispheres 117.9
2334 Male, age 80, both hemispheres 115.4
Periaquaductal grey, anterior
nTPM: 142.1
2502 Female, age 75, unknown 151.3
1947 Male, age 18, unknown 139.2
1795 Male, age 51, unknown 135.8
Periaquaductal grey, dorsal
nTPM: 162.5
2850 Male, age 76, both hemispheres 192.8
2464 Female, age 72, unknown 176.1
1840 Male, age 53, unknown 151.3
1831 Male, age 72, unknown 130.0
Periaquaductal grey, lateral
nTPM: 164.5
2140 Male, age 76, both hemispheres 197.1
2053 Male, age 18, unknown 168.9
2272 Male, age 74, both hemispheres 127.6
Pretectal area
nTPM: 134.8
2316 Male, age 76, right hemisphere 162.5
2825 Male, age 18, unknown 153.0
1817 Female, age 42, unknown 138.8
2407 Male, age 75, both hemispheres 137.6
1815 Male, age 53, unknown 136.5
2667 Female, age 75, unknown 134.0
1944 Female, age 72, unknown 131.8
2273 Male, age 74, both hemispheres 128.7
2224 Female, age 72, unknown 124.3
1816 Male, age 51, unknown 118.9
2007 Male, age 72, unknown 116.9
Red nucleus
nTPM: 188.0
1954 Female, age 42, unknown 223.6
2503 Female, age 72, unknown 218.0
2769 Male, age 72, unknown 208.2
2227 Male, age 72, unknown 205.1
1821 Female, age 72, unknown 202.3
1865 Male, age 51, unknown 194.4
1904 Male, age 53, unknown 187.9
2588 Male, age 74, left hemisphere 182.9
2725 Female, age 75, unknown 176.8
2785 Male, age 18, unknown 164.0
2823 Male, age 76, right hemisphere 159.7
2584 Male, age 75, left hemisphere 133.4
Substantia nigra
nTPM: 158.7
2409 Female, age 72, unknown 191.1
2699 Male, age 18, unknown 181.3
1916 Female, age 42, unknown 175.9
1851 Male, age 51, unknown 169.1
2590 Female, age 75, unknown 161.9
2583 Male, age 75, right hemisphere 149.2
2241 Male, age 72, unknown 148.6
1889 Female, age 72, unknown 138.3
2665 Male, age 74, both hemispheres 137.5
1941 Male, age 53, unknown 134.1
Superior colliculus
nTPM: 149.2
1995 Male, age 72, unknown 192.6
2664 Male, age 75, both hemispheres 184.5
1913 Female, age 42, unknown 156.3
1839 Male, age 51, unknown 150.1
1796 Male, age 53, unknown 148.9
2668 Female, age 75, unknown 141.1
2087 Female, age 72, unknown 136.5
2587 Male, age 74, left hemisphere 133.9
2261 Male, age 18, unknown 127.3
1895 Male, age 76, right hemisphere 120.4
Ventral tegmental area
nTPM: 147.1
2410 Female, age 72, unknown 176.4
1915 Female, age 42, unknown 162.0
1942 Male, age 51, unknown 150.2
2021 Male, age 53, unknown 144.4
2223 Female, age 72, unknown 133.3
2218 Male, age 76, both hemispheres 116.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 110.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 110.0
Samples: 139

Max nTPM: 358.1
Min nTPM: 20.1
Std nTPM: 55.6
Median nTPM: 97.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 358.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 301.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 282.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 262.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 254.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 254.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 237.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 234.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 212.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 205.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 205.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 196.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 180.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 178.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 174.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 174.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 163.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 160.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 156.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 150.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 149.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 149.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 147.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 146.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 146.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 145.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 142.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 138.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 137.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 137.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 137.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 136.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 135.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 132.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 130.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 129.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 129.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 127.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 126.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 123.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 122.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 121.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 120.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 120.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 120.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 118.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 116.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 115.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 115.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 114.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 113.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 112.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 111.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 111.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 111.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 109.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 108.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 107.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 107.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 104.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 104.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 103.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 102.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 102.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 100.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 99.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 99.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 98.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 98.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 97.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 97.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 96.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 95.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 95.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 94.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 92.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 90.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 90.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 88.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 88.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 88.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 88.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 87.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 86.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 86.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 86.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 85.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 84.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 83.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 83.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 82.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 82.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 82.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 81.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 80.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 80.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 79.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 79.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 77.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 77.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 77.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 76.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 75.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 74.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 73.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 73.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 72.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 72.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 72.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 71.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 71.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 70.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 69.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 69.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 68.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 68.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 67.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 64.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 62.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 60.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 60.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 59.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 59.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 58.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 55.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 53.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 52.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 51.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 50.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 49.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 47.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 45.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 45.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 39.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 38.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 37.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 30.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 20.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 329.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 329.0
FF:10158-103A5 76 years, female 329.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 66.3
Pig sample Sample description nTPM
Midbrain
nTPM: 63.7
Samples: 4

Max nTPM: 124.9
Min nTPM: 33.3
Sample A Female 124.9
Sample B Female 48.1
Sample C Male 48.6
Sample D Male 33.3
Periaqueductal gray
nTPM: 66.3
Samples: 3

Max nTPM: 72.3
Min nTPM: 62.9
Sample B Female 62.9
Sample C Male 72.3
Sample D Male 63.7
Substantia nigra
nTPM: 57.2
Samples: 4

Max nTPM: 65.6
Min nTPM: 50.3
Sample A Female 65.6
Sample B Female 51.7
Sample C Male 61.2
Sample D Male 50.3
Superior colliculi
nTPM: 46.4
Samples: 4

Max nTPM: 52.0
Min nTPM: 41.5
Sample A Female 52.0
Sample B Female 41.5
Sample C Male 45.5
Sample D Male 46.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 33.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 33.3
Samples: 4

Max nTPM: 35.6
Min nTPM: 30.2
Sample A Male 35.6
Sample B Male 32.9
Sample C Female 30.2
Sample D Female 34.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.3
69735640 Antisense, RP_050503_03_B11, Mouse strain C57BL/6J (56 days, male) 0.6
73520992 Antisense, RP_051101_02_G11, Mouse strain C57BL/6J (56 days, male) 0.0

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