We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
GUK1
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • GUK1
BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:261.8 nTPM
HPA:261.8 nTPM
FANTOM5:218.0 Scaled Tags Per Million
Pig:92.1 nTPM
Allen mouse:4.9 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 261.8
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 251.0
2301 Female, age 85, both hemispheres 260.2
2090 Male, age 80, both hemispheres 253.8
2188 Female, age 91, both hemispheres 250.2
1984 Male, age 76, both hemispheres 239.9
Dorsal cochlear nucleus
nTPM: 254.1
2802 Male, age 74, right hemisphere 267.5
2187 Female, age 91, both hemispheres 262.2
2058 Male, age 76, both hemispheres 248.3
2370 Male, age 61, both hemispheres 248.1
2378 Male, age 80, both hemispheres 244.3
Dorsal tegmental nucleus
nTPM: 254.5
2083 Male, age 80, both hemispheres 264.0
2326 Male, age 74, both hemispheres 255.3
2358 Male, age 61, both hemispheres 252.6
1936 Male, age 76, left hemisphere 246.2
Dorsolateral tegmental area
nTPM: 251.0
2654 Male, age 80, both hemispheres 264.6
2751 Female, age 85, both hemispheres 259.0
2337 Male, age 61, both hemispheres 253.8
2141 Male, age 76, both hemispheres 243.0
2360 Male, age 74, both hemispheres 234.7
Kolliker-Fuse nucleus
nTPM: 253.4
2163 Male, age 80, both hemispheres 265.6
2793 Female, age 91, left hemisphere 251.9
2315 Male, age 76, right hemisphere 242.7
Lateral lemniscal nuclei
nTPM: 247.6
2169 Male, age 76, both hemispheres 261.2
2453 Male, age 74, right hemisphere 251.0
2746 Female, age 85, left hemisphere 250.8
2320 Female, age 91, left hemisphere 243.6
2036 Male, age 80, both hemispheres 231.4
Lateral parabrachial nucleus
nTPM: 248.9
2139 Female, age 85, right hemisphere 258.0
2013 Male, age 80, both hemispheres 252.8
2790 Male, age 61, both hemispheres 242.7
2792 Male, age 76, both hemispheres 242.0
Lateral vestibular nucleus
nTPM: 261.8
2311 Male, age 80, both hemispheres 261.8
2184 Male, age 76, both hemispheres 261.7
Locus coeruleus
nTPM: 253.8
2123 Female, age 91, both hemispheres 261.7
2162 Male, age 80, both hemispheres 260.2
2720 Male, age 74, both hemispheres 259.5
2014 Male, age 55, unknown 256.3
1980 Male, age 76, both hemispheres 252.7
2317 Female, age 72, unknown 249.6
2788 Male, age 74, unknown 236.6
Medial olivary nucleus
nTPM: 254.2
2138 Female, age 91, both hemispheres 266.3
1943 Male, age 61, both hemispheres 254.6
1962 Male, age 76, both hemispheres 249.9
2851 Male, age 80, both hemispheres 246.1
Medial parabrachial nucleus
nTPM: 259.5
2170 Female, age 91, both hemispheres 287.3
2463 Female, age 85, right hemisphere 259.6
2156 Male, age 61, both hemispheres 257.3
2854 Male, age 80, both hemispheres 247.7
2786 Male, age 76, both hemispheres 245.6
Medial periolivary nuclei
nTPM: 252.9
2063 Male, age 76, both hemispheres 269.7
2171 Female, age 85, both hemispheres 260.7
2081 Male, age 80, both hemispheres 248.8
2458 Female, age 91, both hemispheres 247.4
2791 Male, age 74, right hemisphere 237.8
Motor facial nucleus
nTPM: 253.1
2062 Male, age 76, both hemispheres 275.5
2126 Male, age 61, both hemispheres 257.7
2795 Female, age 91, both hemispheres 254.5
2327 Male, age 80, both hemispheres 246.4
2697 Female, age 85, both hemispheres 243.0
2365 Male, age 74, right hemisphere 241.3
Motor trigeminal nucleus
nTPM: 250.6
2335 Male, age 61, both hemispheres 259.1
2560 Male, age 74, both hemispheres 252.0
2321 Female, age 91, both hemispheres 248.2
2309 Male, age 76, both hemispheres 247.8
2079 Male, age 80, both hemispheres 245.9
Nuclei of the trapezoid body
nTPM: 260.2
1983 Male, age 76, both hemispheres 273.7
2159 Male, age 61, both hemispheres 272.5
2735 Female, age 85, both hemispheres 255.8
2166 Male, age 80, both hemispheres 255.4
2368 Female, age 91, both hemispheres 243.7
Paramedian reticular nucleus
nTPM: 253.7
2057 Male, age 80, both hemispheres 261.5
2050 Female, age 85, both hemispheres 259.4
2313 Male, age 61, both hemispheres 254.8
2052 Male, age 76, both hemispheres 239.1
Pontine nuclei
nTPM: 261.8
1863 Male, age 55, unknown 276.5
2787 Female, age 85, both hemispheres 270.7
1968 Male, age 76, left hemisphere 269.8
2109 Female, age 72, unknown 267.3
2727 Male, age 61, right hemisphere 258.9
2454 Male, age 74, left hemisphere 254.0
2319 Female, age 91, both hemispheres 250.3
2115 Male, age 80, left hemisphere 246.8
Pontine raphe nucleus
nTPM: 251.1
2122 Female, age 85, midline 256.5
2853 Male, age 76, midline 245.7
Posteroventral cochlear nucleus
nTPM: 252.0
2752 Female, age 85, both hemispheres 263.4
2070 Male, age 76, both hemispheres 252.3
2341 Male, age 80, both hemispheres 250.9
2371 Male, age 61, both hemispheres 247.5
2135 Female, age 91, both hemispheres 245.8
Principal sensory trigeminal nucleus
nTPM: 254.7
2158 Male, age 61, both hemispheres 266.0
2324 Male, age 76, both hemispheres 257.7
2367 Female, age 91, left hemisphere 250.5
2008 Male, age 80, left hemisphere 244.6
Reticular pontine nucleus, caudal
nTPM: 256.4
2092 Male, age 76, both hemispheres 259.4
2457 Female, age 91, both hemispheres 258.1
2559 Male, age 74, both hemispheres 256.7
2332 Male, age 80, right hemisphere 251.4
Reticular pontine nucleus, oral
nTPM: 249.9
2167 Male, age 76, both hemispheres 257.1
1939 Male, age 80, both hemispheres 254.6
2012 Female, age 85, both hemispheres 250.6
2366 Female, age 91, both hemispheres 249.0
2361 Male, age 74, both hemispheres 238.1
Reticulotegmental nucleus
nTPM: 256.6
2452 Male, age 74, both hemispheres 263.7
2322 Female, age 91, both hemispheres 263.5
2333 Male, age 80, both hemispheres 249.8
2325 Male, age 76, both hemispheres 249.2
Spinal trigeminal nucleus, oral
nTPM: 256.9
2164 Male, age 80, both hemispheres 269.5
1978 Male, age 76, both hemispheres 255.7
2737 Female, age 85, both hemispheres 245.3
Subcoeruleus area
nTPM: 251.8
2323 Female, age 91, left hemisphere 257.4
2451 Male, age 74, both hemispheres 257.1
2369 Female, age 85, left hemisphere 250.1
1958 Male, age 80, both hemispheres 249.5
2089 Male, age 76, left hemisphere 245.0
Superior olive
nTPM: 247.5
2020 Male, age 76, both hemispheres 252.5
2329 Male, age 80, right hemisphere 252.2
2561 Female, age 91, both hemispheres 251.5
1875 Female, age 85, both hemispheres 243.3
2364 Male, age 74, right hemisphere 238.0
Superior vestibular nucleus
nTPM: 250.6
2015 Male, age 80, both hemispheres 259.2
2061 Male, age 76, both hemispheres 249.3
2383 Male, age 74, both hemispheres 243.1
Ventral periolivary nuclei
nTPM: 251.1
2130 Female, age 85, both hemispheres 260.3
2165 Male, age 80, both hemispheres 259.3
2023 Male, age 76, both hemispheres 245.4
2794 Female, age 91, left hemisphere 239.4
Ventrolateral tegmental area, A5 NE cell group
nTPM: 250.5
2161 Male, age 80, both hemispheres 256.3
1959 Male, age 76, both hemispheres 254.2
2449 Male, age 74, both hemispheres 251.0
2840 Female, age 85, both hemispheres 250.6
2456 Female, age 91, both hemispheres 247.0
2359 Male, age 61, both hemispheres 243.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 218.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 218.0
FF:10182-103D2 60 years, female 234.7
FF:10165-103B3 76 years, female 201.2
Pons
Scaled Tags Per Million: 143.4
FF:10033-101E6 18-54 years, mixed 143.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 92.1
Pig sample Sample description nTPM
Pons
nTPM: 92.1
Samples: 4

Max nTPM: 125.6
Min nTPM: 52.1
Sample A Female 125.6
Sample B Female 52.1
Sample C Male 81.7
Sample D Male 108.9

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.9
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 4.9
2280 Antisense, RP_Baylor_102835, Mouse strain C57BL/6J (56 days, male) 5.1
68443298 Antisense, RP_050111_01_G03, Mouse strain C57BL/6J (56 days, male) 4.7
2279 Antisense, RP_Baylor_102835, Mouse strain C57BL/6J (56 days, male) 2.7

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.