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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:55.4 nTPM
HPA:55.4 nTPM
GTEx:45.5 nTPM
FANTOM5:65.6 Scaled Tags Per Million
Pig:39.2 nTPM
Mouse:86.3 nTPM
Allen mouse:10.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 55.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 51.2
2019 Male, age 18, unknown 55.5
1870 Female, age 42, unknown 55.3
1827 Male, age 72, unknown 52.8
2828 Female, age 72, unknown 51.9
1833 Male, age 53, unknown 51.2
1830 Male, age 51, unknown 50.9
2411 Female, age 72, unknown 50.7
2219 Male, age 76, both hemispheres 49.4
2666 Male, age 74, left hemisphere 47.8
2586 Male, age 75, left hemisphere 46.8
Dorsal raphe nucleus
nTPM: 53.7
2298 Female, age 72, unknown 57.7
2016 Female, age 72, unknown 54.1
1828 Male, age 53, unknown 53.5
2750 Male, age 76, both hemispheres 52.2
2047 Male, age 72, unknown 51.3
Inferior colliculus
nTPM: 53.5
2097 Female, age 72, unknown 56.6
1890 Male, age 53, unknown 53.4
1848 Female, age 42, unknown 52.5
2849 Male, age 72, unknown 51.5
Median raphe nucleus
nTPM: 54.2
2220 Male, age 76, midline 54.2
Pedunculopontine tegmental nucleus
nTPM: 55.4
2338 Male, age 61, both hemispheres 58.9
2334 Male, age 80, both hemispheres 56.5
1921 Female, age 85, both hemispheres 50.8
Periaquaductal grey, anterior
nTPM: 52.4
2502 Female, age 75, unknown 52.8
1947 Male, age 18, unknown 52.7
1795 Male, age 51, unknown 51.6
Periaquaductal grey, dorsal
nTPM: 54.3
2850 Male, age 76, both hemispheres 59.8
1840 Male, age 53, unknown 54.6
1831 Male, age 72, unknown 51.9
2464 Female, age 72, unknown 50.9
Periaquaductal grey, lateral
nTPM: 55.3
2140 Male, age 76, both hemispheres 57.3
2272 Male, age 74, both hemispheres 55.4
2053 Male, age 18, unknown 53.1
Pretectal area
nTPM: 55.0
2273 Male, age 74, both hemispheres 60.0
2007 Male, age 72, unknown 57.4
1817 Female, age 42, unknown 57.1
1815 Male, age 53, unknown 55.8
1816 Male, age 51, unknown 55.8
2224 Female, age 72, unknown 55.4
2667 Female, age 75, unknown 55.2
1944 Female, age 72, unknown 55.0
2316 Male, age 76, right hemisphere 52.5
2825 Male, age 18, unknown 51.3
2407 Male, age 75, both hemispheres 49.2
Red nucleus
nTPM: 53.1
1821 Female, age 72, unknown 56.9
2725 Female, age 75, unknown 55.4
1954 Female, age 42, unknown 55.0
2503 Female, age 72, unknown 54.7
1904 Male, age 53, unknown 54.6
2785 Male, age 18, unknown 54.2
1865 Male, age 51, unknown 53.7
2227 Male, age 72, unknown 52.3
2769 Male, age 72, unknown 52.0
2823 Male, age 76, right hemisphere 50.5
2588 Male, age 74, left hemisphere 49.7
2584 Male, age 75, left hemisphere 48.3
Substantia nigra
nTPM: 52.1
1889 Female, age 72, unknown 54.7
1916 Female, age 42, unknown 53.8
2241 Male, age 72, unknown 53.5
1851 Male, age 51, unknown 53.2
2590 Female, age 75, unknown 52.5
2665 Male, age 74, both hemispheres 52.2
2409 Female, age 72, unknown 51.7
1941 Male, age 53, unknown 50.3
2699 Male, age 18, unknown 49.9
2583 Male, age 75, right hemisphere 49.4
Superior colliculus
nTPM: 52.4
2587 Male, age 74, left hemisphere 55.3
2087 Female, age 72, unknown 55.1
1995 Male, age 72, unknown 54.8
2261 Male, age 18, unknown 54.3
1913 Female, age 42, unknown 54.0
1796 Male, age 53, unknown 52.1
1895 Male, age 76, right hemisphere 51.9
1839 Male, age 51, unknown 51.8
2668 Female, age 75, unknown 49.0
2664 Male, age 75, both hemispheres 46.0
Ventral tegmental area
nTPM: 51.7
1915 Female, age 42, unknown 53.3
2410 Female, age 72, unknown 52.9
2223 Female, age 72, unknown 52.1
2021 Male, age 53, unknown 50.9
2218 Male, age 76, both hemispheres 50.7
1942 Male, age 51, unknown 50.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 45.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 45.5
Samples: 139

Max nTPM: 129.4
Min nTPM: 21.6
Std nTPM: 19.0
Median nTPM: 40.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 129.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 114.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 105.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 102.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 99.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 98.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 94.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 85.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 85.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 69.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 69.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 65.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 64.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 64.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 62.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 62.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 61.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 61.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 61.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 59.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 56.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 56.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 55.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 54.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 53.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 53.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 52.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 51.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 51.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 51.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 50.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 49.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 48.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 48.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 48.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 47.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 47.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 46.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 45.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 45.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 45.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 45.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 45.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 45.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 44.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 44.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 44.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 44.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 43.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 43.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 43.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 42.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 42.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 42.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 41.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 41.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 41.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 40.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 40.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 40.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 40.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 40.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 40.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 39.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 39.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 39.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 38.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 38.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 38.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 38.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 38.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 38.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 37.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 37.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 37.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 37.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 37.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 36.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 36.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 36.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 36.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 35.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 35.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 35.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 35.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 35.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 35.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 34.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 34.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 34.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 34.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 34.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 34.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 33.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 33.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 33.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 33.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 33.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 33.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 33.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 33.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 32.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 32.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 32.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 32.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 31.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 31.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 31.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 30.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 30.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 30.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 30.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 29.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 29.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 29.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 28.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 28.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 28.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 28.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 28.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 27.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 27.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 27.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 27.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 26.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 26.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 26.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 26.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 21.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 65.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 65.6
FF:10158-103A5 76 years, female 65.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 39.2
Pig sample Sample description nTPM
Midbrain
nTPM: 38.4
Samples: 4

Max nTPM: 58.3
Min nTPM: 28.6
Sample A Female 58.3
Sample B Female 33.9
Sample C Male 32.7
Sample D Male 28.6
Periaqueductal gray
nTPM: 31.5
Samples: 3

Max nTPM: 33.8
Min nTPM: 30.2
Sample B Female 33.8
Sample C Male 30.6
Sample D Male 30.2
Substantia nigra
nTPM: 35.4
Samples: 4

Max nTPM: 41.2
Min nTPM: 31.8
Sample A Female 41.2
Sample B Female 34.3
Sample C Male 31.8
Sample D Male 34.4
Superior colliculi
nTPM: 39.3
Samples: 4

Max nTPM: 45.4
Min nTPM: 33.9
Sample A Female 43.3
Sample B Female 45.4
Sample C Male 33.9
Sample D Male 34.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 86.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 86.3
Samples: 4

Max nTPM: 96.9
Min nTPM: 77.2
Sample A Male 77.2
Sample B Male 79.6
Sample C Female 91.4
Sample D Female 96.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.0
69079989 Antisense, RP_050324_01_B04, Mouse strain C57BL/6J (56 days, male) 10.0

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