GENERAL INFORMATIONi
Gene namei SNCA
Synonyms NACP, PARK1, PARK4, PD1
Gene descriptioni Synuclein alpha
Protein classi Disease related genes
Human disease related genes
Plasma proteins
Potential drug targets
Transporters
Predicted locationi Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi
Chromosome 4
Cytoband q22.1
Chromosome location (bp) 89700345 - 89838315
Number of transcriptsi 16
Ensembl ENSG00000145335 (version 103.38)
Entrez gene 6622
HGNC HGNC:11138
UniProt P37840 (UniProt - Evidence at protein level)
neXtProt NX_P37840
Antibodypedia SNCA antibodies


PROTEIN STRUCTUREi

Predicted


Description: Structure prediction from Alphafold project. Structure version 2

# Chains: 1      # Clinical variants: 5      # Population variants: 70

Experimental

Description: Human micelle-bound alpha-synuclein (NMR)

# Chains: 1      # Clinical variants: 5      # Population variants: 70

Antigens:

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Variants:

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Clinical
Population

Color scheme:

Confidence
Residue index
Chain name

Autorotate:

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PROTEIN BROWSERi
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SNCA-201
SNCA-202
SNCA-203
SNCA-204
SNCA-205
SNCA-206
SNCA-207
SNCA-208
SNCA-209
SNCA-210
SNCA-211
SNCA-212
SNCA-213
SNCA-214
SNCA-216
SNCA-217
»


PROTEIN INFORMATIONi
Splice variant UniProt Protein class Gene ontology Length & mass Signal peptide
(predicted)		 Transmembrane regions
(predicted)
SNCA-201
ENSP00000338345
ENST00000336904
P37840 [Direct mapping]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 140 aa
14.5 kDa 		No 0
SNCA-202
ENSP00000343683
ENST00000345009
P37840 [Direct mapping]
Alpha-synuclein
H6UYS5 [Target identity:100%; Query identity:100%]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 112 aa
11.4 kDa 		No 0
SNCA-203
ENSP00000378437
ENST00000394986
P37840 [Direct mapping]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 140 aa
14.5 kDa 		No 0
SNCA-204
ENSP00000378440
ENST00000394989
P37840 [Direct mapping]
Alpha-synuclein
H6UYS0 [Target identity:100%; Query identity:100%]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 126 aa
13.1 kDa 		No 0
SNCA-205
ENSP00000378442
ENST00000394991
P37840 [Direct mapping]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 140 aa
14.5 kDa 		No 0
SNCA-206
ENSP00000396241
ENST00000420646
P37840 [Direct mapping]
Alpha-synuclein
H6UYS5 [Target identity:100%; Query identity:100%]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 112 aa
11.4 kDa 		No 0
SNCA-207
ENSP00000426034
ENST00000502987
E7EPV7 [Direct mapping]
Alpha-synuclein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0014059 [regulation of dopamine secretion]
GO:0016020 [membrane]
GO:0045202 [synapse]
Show all
 115 aa
11.8 kDa 		No 0
SNCA-208
ENSP00000421485
ENST00000505199
P37840 [Direct mapping]
Alpha-synuclein
H6UYS0 [Target identity:100%; Query identity:100%]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 126 aa
13.1 kDa 		No 0
SNCA-209
ENSP00000422238
ENST00000506244
P37840 [Direct mapping]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 140 aa
14.5 kDa 		No 0
SNCA-210
ENSP00000423445
ENST00000506691
D6RA31 [Direct mapping]
Alpha-synuclein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0014059 [regulation of dopamine secretion]
GO:0016020 [membrane]
GO:0045202 [synapse]
Show all
 66 aa
6.8 kDa 		No 0
SNCA-211
ENSP00000426955
ENST00000508895
P37840 [Direct mapping]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 140 aa
14.5 kDa 		No 0
SNCA-212
ENSP00000479604
ENST00000611107
H6UYS7 [Direct mapping]
Alpha-synuclein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0014059 [regulation of dopamine secretion]
GO:0016020 [membrane]
GO:0045202 [synapse]
Show all
 98 aa
10 kDa 		No 0
SNCA-213
ENSP00000484044
ENST00000618500
P37840 [Direct mapping]
Alpha-synuclein
H6UYS0 [Target identity:100%; Query identity:100%]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 126 aa
13.1 kDa 		No 0
SNCA-214
ENSP00000500990
ENST00000673718
P37840 [Direct mapping]
Alpha-synuclein
Show all
Transporters
   Transporter channels and pores
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Disease related genes
Potential drug targets
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000149 [SNARE binding]
GO:0000287 [magnesium ion binding]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0001774 [microglial cell activation]
GO:0001921 [positive regulation of receptor recycling]
GO:0003779 [actin binding]
GO:0004860 [protein kinase inhibitor activity]
GO:0005507 [copper ion binding]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005938 [cell cortex]
GO:0006469 [negative regulation of protein kinase activity]
GO:0006915 [apoptotic process]
GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0007268 [chemical synaptic transmission]
GO:0008198 [ferrous iron binding]
GO:0008270 [zinc ion binding]
GO:0010040 [response to iron(II) ion]
GO:0010517 [regulation of phospholipase activity]
GO:0010642 [negative regulation of platelet-derived growth factor receptor signaling pathway]
GO:0014059 [regulation of dopamine secretion]
GO:0015629 [actin cytoskeleton]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0016082 [synaptic vesicle priming]
GO:0016234 [inclusion body]
GO:0016491 [oxidoreductase activity]
GO:0019894 [kinesin binding]
GO:0022898 [regulation of transmembrane transporter activity]
GO:0030054 [cell junction]
GO:0030424 [axon]
GO:0030426 [growth cone]
GO:0030544 [Hsp70 protein binding]
GO:0031092 [platelet alpha granule membrane]
GO:0031115 [negative regulation of microtubule polymerization]
GO:0031623 [receptor internalization]
GO:0031648 [protein destabilization]
GO:0032026 [response to magnesium ion]
GO:0032410 [negative regulation of transporter activity]
GO:0032496 [response to lipopolysaccharide]
GO:0032769 [negative regulation of monooxygenase activity]
GO:0032991 [protein-containing complex]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034341 [response to interferon-gamma]
GO:0034599 [cellular response to oxidative stress]
GO:0035067 [negative regulation of histone acetylation]
GO:0035493 [SNARE complex assembly]
GO:0035543 [positive regulation of SNARE complex assembly]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042802 [identical protein binding]
GO:0043014 [alpha-tubulin binding]
GO:0043025 [neuronal cell body]
GO:0043027 [cysteine-type endopeptidase inhibitor activity involved in apoptotic process]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process]
GO:0043679 [axon terminus]
GO:0044267 [cellular protein metabolic process]
GO:0045202 [synapse]
GO:0045807 [positive regulation of endocytosis]
GO:0045920 [negative regulation of exocytosis]
GO:0045921 [positive regulation of exocytosis]
GO:0046872 [metal ion binding]
GO:0048156 [tau protein binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050729 [positive regulation of inflammatory response]
GO:0050808 [synapse organization]
GO:0051219 [phosphoprotein binding]
GO:0051262 [protein tetramerization]
GO:0051281 [positive regulation of release of sequestered calcium ion into cytosol]
GO:0051583 [dopamine uptake involved in synaptic transmission]
GO:0051585 [negative regulation of dopamine uptake involved in synaptic transmission]
GO:0051612 [negative regulation of serotonin uptake]
GO:0051621 [regulation of norepinephrine uptake]
GO:0051622 [negative regulation of norepinephrine uptake]
GO:0055114 [oxidation-reduction process]
GO:0060732 [positive regulation of inositol phosphate biosynthetic process]
GO:0070495 [negative regulation of thrombin-activated receptor signaling pathway]
GO:0070555 [response to interleukin-1]
GO:0070840 [dynein complex binding]
GO:0071280 [cellular response to copper ion]
GO:0071872 [cellular response to epinephrine stimulus]
GO:0071902 [positive regulation of protein serine/threonine kinase activity]
GO:0097435 [supramolecular fiber organization]
GO:0099512 [supramolecular fiber]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1901216 [positive regulation of neuron death]
GO:1902957 [negative regulation of mitochondrial electron transport, NADH to ubiquinone]
GO:1903136 [cuprous ion binding]
GO:1903284 [positive regulation of glutathione peroxidase activity]
GO:1903285 [positive regulation of hydrogen peroxide catabolic process]
GO:1903421 [regulation of synaptic vesicle recycling]
GO:1903426 [regulation of reactive oxygen species biosynthetic process]
GO:1904715 [negative regulation of chaperone-mediated autophagy]
GO:1905606 [regulation of presynapse assembly]
Show all
 140 aa
14.5 kDa 		No 0
SNCA-216
ENSP00000501102
ENST00000673902
A0A669KB41 [Direct mapping]
Alpha-synuclein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0014059 [regulation of dopamine secretion]
GO:0016020 [membrane]
GO:0045202 [synapse]
Show all
 151 aa
15.5 kDa 		No 0
SNCA-217
ENSP00000501269
ENST00000674129
A0A669KBH5 [Direct mapping]
Alpha-synuclein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Nervous system diseases
   Neurodegenerative diseases
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001774 [microglial cell activation]
GO:0001933 [negative regulation of protein phosphorylation]
GO:0001956 [positive regulation of neurotransmitter secretion]
GO:0001963 [synaptic transmission, dopaminergic]
GO:0005543 [phospholipid binding]
GO:0005576 [extracellular region]
GO:0005634 [nucleus]
GO:0005640 [nuclear outer membrane]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005743 [mitochondrial inner membrane]
GO:0005758 [mitochondrial intermembrane space]
GO:0005759 [mitochondrial matrix]
GO:0005791 [rough endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0006631 [fatty acid metabolic process]
GO:0006638 [neutral lipid metabolic process]
GO:0006644 [phospholipid metabolic process]
GO:0007006 [mitochondrial membrane organization]
GO:0007268 [chemical synaptic transmission]
GO:0007568 [aging]
GO:0008017 [microtubule binding]
GO:0008021 [synaptic vesicle]
GO:0008344 [adult locomotory behavior]
GO:0014048 [regulation of glutamate secretion]
GO:0014059 [regulation of dopamine secretion]
GO:0016020 [membrane]
GO:0016234 [inclusion body]
GO:0019899 [enzyme binding]
GO:0019904 [protein domain specific binding]
GO:0030426 [growth cone]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0030672 [synaptic vesicle membrane]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0034599 [cellular response to oxidative stress]
GO:0035493 [SNARE complex assembly]
GO:0040012 [regulation of locomotion]
GO:0042220 [response to cocaine]
GO:0042393 [histone binding]
GO:0042416 [dopamine biosynthetic process]
GO:0042417 [dopamine metabolic process]
GO:0042493 [response to drug]
GO:0042775 [mitochondrial ATP synthesis coupled electron transport]
GO:0042802 [identical protein binding]
GO:0043025 [neuronal cell body]
GO:0043030 [regulation of macrophage activation]
GO:0043195 [terminal bouton]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0043274 [phospholipase binding]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0043679 [axon terminus]
GO:0044344 [cellular response to fibroblast growth factor stimulus]
GO:0045202 [synapse]
GO:0045963 [negative regulation of dopamine metabolic process]
GO:0046928 [regulation of neurotransmitter secretion]
GO:0047485 [protein N-terminus binding]
GO:0048148 [behavioral response to cocaine]
GO:0048168 [regulation of neuronal synaptic plasticity]
GO:0048169 [regulation of long-term neuronal synaptic plasticity]
GO:0048487 [beta-tubulin binding]
GO:0048488 [synaptic vesicle endocytosis]
GO:0048489 [synaptic vesicle transport]
GO:0050544 [arachidonic acid binding]
GO:0050806 [positive regulation of synaptic transmission]
GO:0050808 [synapse organization]
GO:0050812 [regulation of acyl-CoA biosynthetic process]
GO:0051259 [protein complex oligomerization]
GO:0060079 [excitatory postsynaptic potential]
GO:0060291 [long-term synaptic potentiation]
GO:0061024 [membrane organization]
GO:0098793 [presynapse]
GO:1901214 [regulation of neuron death]
GO:1901215 [negative regulation of neuron death]
GO:1904307 [response to desipramine]
GO:2000377 [regulation of reactive oxygen species metabolic process]
Show all
 159 aa
16.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.