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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:75.8 nTPM
HPA:75.8 nTPM
GTEx:68.2 nTPM
FANTOM5:16.9 Scaled Tags Per Million
Pig:75.4 nTPM
Mouse:54.9 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 75.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 56.9
1827 Male, age 72, unknown 59.1
2019 Male, age 18, unknown 59.0
2411 Female, age 72, unknown 57.1
1870 Female, age 42, unknown 57.0
2828 Female, age 72, unknown 57.0
1833 Male, age 53, unknown 56.7
1830 Male, age 51, unknown 56.0
2586 Male, age 75, left hemisphere 55.7
2666 Male, age 74, left hemisphere 55.5
2219 Male, age 76, both hemispheres 55.4
Dorsal raphe nucleus
nTPM: 65.9
2298 Female, age 72, unknown 78.0
2016 Female, age 72, unknown 71.0
1828 Male, age 53, unknown 62.9
2047 Male, age 72, unknown 60.7
2750 Male, age 76, both hemispheres 57.0
Inferior colliculus
nTPM: 58.4
2097 Female, age 72, unknown 60.3
2849 Male, age 72, unknown 58.6
1890 Male, age 53, unknown 57.6
1848 Female, age 42, unknown 57.2
Median raphe nucleus
nTPM: 61.3
2220 Male, age 76, midline 61.3
Pedunculopontine tegmental nucleus
nTPM: 58.4
2338 Male, age 61, both hemispheres 59.3
2334 Male, age 80, both hemispheres 58.5
1921 Female, age 85, both hemispheres 57.5
Periaquaductal grey, anterior
nTPM: 62.5
1795 Male, age 51, unknown 65.4
1947 Male, age 18, unknown 61.8
2502 Female, age 75, unknown 60.3
Periaquaductal grey, dorsal
nTPM: 67.8
2850 Male, age 76, both hemispheres 80.2
1840 Male, age 53, unknown 67.3
1831 Male, age 72, unknown 62.5
2464 Female, age 72, unknown 61.2
Periaquaductal grey, lateral
nTPM: 75.8
2272 Male, age 74, both hemispheres 94.2
2140 Male, age 76, both hemispheres 72.7
2053 Male, age 18, unknown 60.6
Pretectal area
nTPM: 63.6
2273 Male, age 74, both hemispheres 88.5
2224 Female, age 72, unknown 68.7
2667 Female, age 75, unknown 61.9
1816 Male, age 51, unknown 61.8
1817 Female, age 42, unknown 61.6
1815 Male, age 53, unknown 61.5
2825 Male, age 18, unknown 61.2
1944 Female, age 72, unknown 60.7
2007 Male, age 72, unknown 59.6
2407 Male, age 75, both hemispheres 57.5
2316 Male, age 76, right hemisphere 56.5
Red nucleus
nTPM: 56.6
2725 Female, age 75, unknown 59.8
2785 Male, age 18, unknown 59.5
2769 Male, age 72, unknown 57.2
2227 Male, age 72, unknown 57.0
2503 Female, age 72, unknown 56.8
1954 Female, age 42, unknown 56.7
1821 Female, age 72, unknown 56.5
1865 Male, age 51, unknown 56.5
1904 Male, age 53, unknown 55.9
2823 Male, age 76, right hemisphere 54.8
2588 Male, age 74, left hemisphere 54.5
2584 Male, age 75, left hemisphere 54.4
Substantia nigra
nTPM: 58.7
1941 Male, age 53, unknown 60.4
2699 Male, age 18, unknown 60.1
2590 Female, age 75, unknown 60.0
1916 Female, age 42, unknown 59.8
1889 Female, age 72, unknown 59.7
1851 Male, age 51, unknown 59.1
2241 Male, age 72, unknown 58.5
2409 Female, age 72, unknown 57.4
2665 Male, age 74, both hemispheres 56.2
2583 Male, age 75, right hemisphere 55.9
Superior colliculus
nTPM: 59.9
2587 Male, age 74, left hemisphere 65.4
1995 Male, age 72, unknown 64.5
2261 Male, age 18, unknown 61.6
2087 Female, age 72, unknown 59.8
2664 Male, age 75, both hemispheres 59.1
1796 Male, age 53, unknown 59.0
1839 Male, age 51, unknown 58.2
1913 Female, age 42, unknown 58.2
2668 Female, age 75, unknown 56.9
1895 Male, age 76, right hemisphere 56.0
Ventral tegmental area
nTPM: 59.2
2021 Male, age 53, unknown 61.3
1915 Female, age 42, unknown 60.2
1942 Male, age 51, unknown 59.3
2218 Male, age 76, both hemispheres 58.6
2223 Female, age 72, unknown 58.2
2410 Female, age 72, unknown 57.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 68.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 68.2
Samples: 139

Max nTPM: 188.7
Min nTPM: 18.8
Std nTPM: 22.1
Median nTPM: 63.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 188.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 134.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 130.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 123.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 122.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 111.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 107.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 106.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 99.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 96.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 94.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 93.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 93.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 92.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 92.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 91.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 91.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 91.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 89.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 89.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 88.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 88.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 88.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 87.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 87.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 86.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 85.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 84.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 83.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 83.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 82.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 81.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 81.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 80.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 79.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 78.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 78.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 77.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 76.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 76.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 75.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 75.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 74.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 73.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 73.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 73.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 72.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 72.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 71.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 71.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 70.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 70.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 68.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 68.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 68.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 68.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 67.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 66.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 65.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 65.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 65.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 65.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 64.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 63.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 63.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 63.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 63.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 63.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 63.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 63.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 62.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 62.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 62.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 61.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 61.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 61.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 61.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 61.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 60.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 60.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 59.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 59.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 59.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 59.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 59.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 59.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 59.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 59.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 58.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 58.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 58.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 58.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 58.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 57.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 57.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 57.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 57.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 56.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 56.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 56.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 55.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 55.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 55.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 55.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 54.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 53.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 52.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 51.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 51.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 51.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 51.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 50.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 50.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 50.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 49.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 49.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 49.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 48.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 48.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 47.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 47.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 46.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 46.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 45.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 43.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 43.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 43.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 43.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 42.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 40.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 39.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 39.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 38.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 37.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 34.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 31.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 16.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 16.9
FF:10158-103A5 76 years, female 16.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 75.4
Pig sample Sample description nTPM
Midbrain
nTPM: 49.4
Samples: 4

Max nTPM: 69.4
Min nTPM: 37.3
Sample A Female 69.4
Sample B Female 50.5
Sample C Male 37.3
Sample D Male 40.3
Periaqueductal gray
nTPM: 75.4
Samples: 3

Max nTPM: 87.7
Min nTPM: 60.7
Sample B Female 60.7
Sample C Male 77.7
Sample D Male 87.7
Substantia nigra
nTPM: 40.1
Samples: 4

Max nTPM: 50.3
Min nTPM: 35.1
Sample A Female 50.3
Sample B Female 36.4
Sample C Male 38.5
Sample D Male 35.1
Superior colliculi
nTPM: 48.1
Samples: 4

Max nTPM: 54.3
Min nTPM: 43.3
Sample A Female 54.3
Sample B Female 51.0
Sample C Male 43.3
Sample D Male 43.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 54.9
Samples: 4

Max nTPM: 56.5
Min nTPM: 51.3
Sample A Male 55.6
Sample B Male 56.5
Sample C Female 51.3
Sample D Female 56.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
69838701 Antisense, RP_050317_04_F04, Mouse strain C57BL/6J (56 days, male) 0.8
77910681 Antisense, RP_070208_04_E11, Mouse strain C57BL/6J (56 days, male) 0.0

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