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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:277.8 nTPM
HPA:277.8 nTPM
GTEx:478.8 nTPM
FANTOM5:290.2 Scaled Tags Per Million
Pig:188.1 nTPM
Mouse:470.0 nTPM
Allen mouse:6.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 277.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 256.8
2019 Male, age 18, unknown 273.7
1870 Female, age 42, unknown 271.8
2219 Male, age 76, both hemispheres 259.9
2411 Female, age 72, unknown 256.7
1827 Male, age 72, unknown 256.4
2666 Male, age 74, left hemisphere 252.9
2828 Female, age 72, unknown 250.3
1833 Male, age 53, unknown 250.2
2586 Male, age 75, left hemisphere 249.4
1830 Male, age 51, unknown 246.5
Dorsal raphe nucleus
nTPM: 251.8
1828 Male, age 53, unknown 262.0
2750 Male, age 76, both hemispheres 257.6
2298 Female, age 72, unknown 249.5
2047 Male, age 72, unknown 246.4
2016 Female, age 72, unknown 243.4
Inferior colliculus
nTPM: 266.9
1890 Male, age 53, unknown 278.1
2097 Female, age 72, unknown 276.1
1848 Female, age 42, unknown 260.9
2849 Male, age 72, unknown 252.6
Median raphe nucleus
nTPM: 253.3
2220 Male, age 76, midline 253.3
Pedunculopontine tegmental nucleus
nTPM: 269.0
2338 Male, age 61, both hemispheres 273.0
2334 Male, age 80, both hemispheres 272.9
1921 Female, age 85, both hemispheres 261.2
Periaquaductal grey, anterior
nTPM: 250.7
2502 Female, age 75, unknown 253.4
1947 Male, age 18, unknown 249.4
1795 Male, age 51, unknown 249.1
Periaquaductal grey, dorsal
nTPM: 243.1
2850 Male, age 76, both hemispheres 248.4
1831 Male, age 72, unknown 243.3
1840 Male, age 53, unknown 241.9
2464 Female, age 72, unknown 239.0
Periaquaductal grey, lateral
nTPM: 239.5
2053 Male, age 18, unknown 243.7
2140 Male, age 76, both hemispheres 238.5
2272 Male, age 74, both hemispheres 236.2
Pretectal area
nTPM: 255.9
2007 Male, age 72, unknown 279.3
1817 Female, age 42, unknown 276.2
1944 Female, age 72, unknown 274.4
1816 Male, age 51, unknown 267.9
1815 Male, age 53, unknown 259.1
2667 Female, age 75, unknown 256.1
2224 Female, age 72, unknown 247.0
2316 Male, age 76, right hemisphere 246.6
2825 Male, age 18, unknown 245.9
2273 Male, age 74, both hemispheres 232.0
2407 Male, age 75, both hemispheres 230.4
Red nucleus
nTPM: 277.8
2503 Female, age 72, unknown 296.2
2725 Female, age 75, unknown 292.4
1821 Female, age 72, unknown 290.4
2588 Male, age 74, left hemisphere 290.1
1865 Male, age 51, unknown 280.1
2769 Male, age 72, unknown 277.5
1954 Female, age 42, unknown 274.4
2823 Male, age 76, right hemisphere 272.7
2227 Male, age 72, unknown 272.5
2785 Male, age 18, unknown 272.1
1904 Male, age 53, unknown 269.0
2584 Male, age 75, left hemisphere 245.7
Substantia nigra
nTPM: 267.7
1916 Female, age 42, unknown 290.8
1889 Female, age 72, unknown 284.2
1851 Male, age 51, unknown 274.2
2409 Female, age 72, unknown 274.0
2665 Male, age 74, both hemispheres 269.8
1941 Male, age 53, unknown 266.9
2241 Male, age 72, unknown 265.3
2699 Male, age 18, unknown 263.3
2583 Male, age 75, right hemisphere 246.2
2590 Female, age 75, unknown 242.4
Superior colliculus
nTPM: 251.0
1895 Male, age 76, right hemisphere 268.4
2668 Female, age 75, unknown 257.3
2087 Female, age 72, unknown 256.5
1796 Male, age 53, unknown 256.2
2587 Male, age 74, left hemisphere 255.7
1913 Female, age 42, unknown 253.9
1995 Male, age 72, unknown 248.2
1839 Male, age 51, unknown 246.7
2261 Male, age 18, unknown 244.8
2664 Male, age 75, both hemispheres 222.1
Ventral tegmental area
nTPM: 262.7
2223 Female, age 72, unknown 278.1
1915 Female, age 42, unknown 269.1
2218 Male, age 76, both hemispheres 268.4
2410 Female, age 72, unknown 263.4
1942 Male, age 51, unknown 254.0
2021 Male, age 53, unknown 243.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 478.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 478.8
Samples: 139

Max nTPM: 1367.1
Min nTPM: 227.9
Std nTPM: 161.2
Median nTPM: 450.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1367.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1035.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 908.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 874.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 858.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 807.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 785.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 747.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 714.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 695.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 674.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 664.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 660.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 657.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 644.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 639.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 623.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 617.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 612.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 611.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 610.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 603.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 600.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 596.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 588.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 585.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 585.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 583.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 582.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 582.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 579.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 574.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 571.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 562.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 559.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 556.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 556.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 550.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 545.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 542.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 539.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 536.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 534.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 532.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 529.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 527.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 523.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 520.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 515.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 506.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 505.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 501.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 494.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 490.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 489.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 486.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 484.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 483.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 482.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 481.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 471.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 468.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 465.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 460.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 457.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 456.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 452.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 452.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 451.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 450.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 449.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 448.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 446.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 444.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 442.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 439.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 435.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 434.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 430.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 425.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 425.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 424.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 423.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 421.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 421.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 420.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 419.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 418.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 416.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 413.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 411.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 407.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 406.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 405.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 405.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 405.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 394.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 392.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 388.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 387.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 375.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 373.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 373.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 369.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 366.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 364.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 362.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 360.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 359.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 356.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 355.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 354.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 351.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 346.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 342.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 337.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 336.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 334.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 332.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 325.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 324.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 324.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 318.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 314.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 314.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 310.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 309.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 302.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 297.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 280.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 271.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 268.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 266.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 265.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 261.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 254.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 250.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 249.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 227.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 290.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 290.2
FF:10158-103A5 76 years, female 290.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 188.1
Pig sample Sample description nTPM
Midbrain
nTPM: 167.2
Samples: 4

Max nTPM: 212.2
Min nTPM: 141.1
Sample A Female 164.7
Sample B Female 141.1
Sample C Male 212.2
Sample D Male 150.9
Periaqueductal gray
nTPM: 112.9
Samples: 3

Max nTPM: 128.7
Min nTPM: 99.1
Sample B Female 110.9
Sample C Male 128.7
Sample D Male 99.1
Substantia nigra
nTPM: 137.6
Samples: 4

Max nTPM: 188.8
Min nTPM: 106.8
Sample A Female 188.8
Sample B Female 106.9
Sample C Male 147.7
Sample D Male 106.8
Superior colliculi
nTPM: 188.2
Samples: 4

Max nTPM: 238.1
Min nTPM: 144.9
Sample A Female 209.2
Sample B Female 144.9
Sample C Male 238.1
Sample D Male 160.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 470.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 470.0
Samples: 4

Max nTPM: 517.4
Min nTPM: 439.0
Sample A Male 517.4
Sample B Male 441.9
Sample C Female 439.0
Sample D Female 481.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.1
68631911 Antisense, RP_050125_01_C12, Mouse strain C57BL/6J (56 days, male) 6.1

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