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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Cancer-related genes Disease related genes Human disease related genes Plasma proteins
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
9
Cytoband
p21.3
Chromosome location (bp)
21967752 - 21995301
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
The Structure section provides predicted structures from the Alphafold protein structure database and available experimental structures from Protein Data Bank (PDB).
In the Structure drop-down menu all experimental structures from PDB are available for selection and display. The structures are displayed using the NGL Viewer and can be zoomed-in and rotated either manually or by checking the Autorotate box. The Color scheme can be selected to show the residue index, chain name or confidence score (as B-factors and pLDDT score for experimental and predicted structures, respectively). The positions for available antigen sequences in the structure are shown if Antigens is turned to ON, and the Variants slider can be used to show the positions of clinical and population variants.https://github.com/nglviewer/ngl
The protein browser displays the antigen location on the target protein(s) and the features of the target protein. The tabs at the top of the protein view section can be used to switch between the different splice variants to which an antigen has been mapped.
At the top of the view, the position of the antigen (identified by the corresponding HPA identifier) is shown as a green bar. A yellow triangle on the bar indicates a <100% sequence identity to the protein target.
Below the antigens, the maximum percent sequence identity of the protein to all other proteins from other human genes is displayed, using a sliding window of 10 aa residues (HsID 10) or 50 aa residues (HsID 50). The region with the lowest possible identity is always selected for antigen design, with a maximum identity of 60% allowed for designing a single-target antigen (read more).
The curve in blue displays the predicted antigenicity i.e. the tendency for different regions of the protein to generate an immune response, with peak regions being predicted to be more antigenic.The curve shows average values based on a sliding window approach using an in-house propensity scale. (read more).
If a signal peptide is predicted by a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius (turquoise) and/or transmembrane regions (orange) are predicted by MDM, these are displayed.
Low complexity regions are shown in yellow and InterPro regions in green. Common (purple) and unique (grey) regions between different splice variants of the gene are also displayed (read more), and at the bottom of the protein view is the protein scale.
CDKN2A-201
CDKN2A-205
CDKN2A-206
CDKN2A-207
CDKN2A-208
CDKN2A-209
CDKN2A-210
CDKN2A-212
CDKN2A-213
CDKN2A-214
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Candidate cancer biomarkers Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Disease related genes Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000082 [G1/S transition of mitotic cell cycle] GO:0001953 [negative regulation of cell-matrix adhesion] GO:0003723 [RNA binding] GO:0004861 [cyclin-dependent protein serine/threonine kinase inhibitor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0007265 [Ras protein signal transduction] GO:0008285 [negative regulation of cell population proliferation] GO:0016301 [kinase activity] GO:0016310 [phosphorylation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0032088 [negative regulation of NF-kappaB transcription factor activity] GO:0034393 [positive regulation of smooth muscle cell apoptotic process] GO:0035985 [senescence-associated heterochromatin focus] GO:0035986 [senescence-associated heterochromatin focus assembly] GO:0042326 [negative regulation of phosphorylation] GO:0045736 [negative regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0051059 [NF-kappaB binding] GO:0090398 [cellular senescence] GO:0090399 [replicative senescence] GO:2000111 [positive regulation of macrophage apoptotic process] GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle] GO:2000774 [positive regulation of cellular senescence]
Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Disease related genes Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000082 [G1/S transition of mitotic cell cycle] GO:0001953 [negative regulation of cell-matrix adhesion] GO:0003723 [RNA binding] GO:0004861 [cyclin-dependent protein serine/threonine kinase inhibitor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0007265 [Ras protein signal transduction] GO:0008285 [negative regulation of cell population proliferation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0032088 [negative regulation of NF-kappaB transcription factor activity] GO:0034393 [positive regulation of smooth muscle cell apoptotic process] GO:0035985 [senescence-associated heterochromatin focus] GO:0035986 [senescence-associated heterochromatin focus assembly] GO:0042326 [negative regulation of phosphorylation] GO:0045736 [negative regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0051059 [NF-kappaB binding] GO:0090398 [cellular senescence] GO:0090399 [replicative senescence] GO:2000111 [positive regulation of macrophage apoptotic process] GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle] GO:2000774 [positive regulation of cellular senescence]
Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Candidate cancer biomarkers Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Disease related genes Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000082 [G1/S transition of mitotic cell cycle] GO:0001953 [negative regulation of cell-matrix adhesion] GO:0003723 [RNA binding] GO:0004861 [cyclin-dependent protein serine/threonine kinase inhibitor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0007265 [Ras protein signal transduction] GO:0008285 [negative regulation of cell population proliferation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0032088 [negative regulation of NF-kappaB transcription factor activity] GO:0034393 [positive regulation of smooth muscle cell apoptotic process] GO:0035985 [senescence-associated heterochromatin focus] GO:0035986 [senescence-associated heterochromatin focus assembly] GO:0042326 [negative regulation of phosphorylation] GO:0045736 [negative regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0051059 [NF-kappaB binding] GO:0090398 [cellular senescence] GO:0090399 [replicative senescence] GO:2000111 [positive regulation of macrophage apoptotic process] GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle] GO:2000774 [positive regulation of cellular senescence]
Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Disease related genes Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle] GO:0001953 [negative regulation of cell-matrix adhesion] GO:0003723 [RNA binding] GO:0004861 [cyclin-dependent protein serine/threonine kinase inhibitor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0007265 [Ras protein signal transduction] GO:0008285 [negative regulation of cell population proliferation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0032088 [negative regulation of NF-kappaB transcription factor activity] GO:0034393 [positive regulation of smooth muscle cell apoptotic process] GO:0035985 [senescence-associated heterochromatin focus] GO:0035986 [senescence-associated heterochromatin focus assembly] GO:0042326 [negative regulation of phosphorylation] GO:0045736 [negative regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0051059 [NF-kappaB binding] GO:0090398 [cellular senescence] GO:0090399 [replicative senescence] GO:2000111 [positive regulation of macrophage apoptotic process] GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle] GO:2000774 [positive regulation of cellular senescence]
Phobius predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000209 [protein polyubiquitination] GO:0002039 [p53 binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005739 [mitochondrion] GO:0006364 [rRNA processing] GO:0006469 [negative regulation of protein kinase activity] GO:0006915 [apoptotic process] GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0008134 [transcription factor binding] GO:0008285 [negative regulation of cell population proliferation] GO:0008637 [apoptotic mitochondrial changes] GO:0010389 [regulation of G2/M transition of mitotic cell cycle] GO:0010628 [positive regulation of gene expression] GO:0016604 [nuclear body] GO:0016925 [protein sumoylation] GO:0019789 [SUMO transferase activity] GO:0030889 [negative regulation of B cell proliferation] GO:0031647 [regulation of protein stability] GO:0031648 [protein destabilization] GO:0032991 [protein-containing complex] GO:0033088 [negative regulation of immature T cell proliferation in thymus] GO:0033235 [positive regulation of protein sumoylation] GO:0043065 [positive regulation of apoptotic process] GO:0043517 [positive regulation of DNA damage response, signal transduction by p53 class mediator] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription by RNA polymerase II] GO:0046825 [regulation of protein export from nucleus] GO:0048103 [somatic stem cell division] GO:0050821 [protein stabilization] GO:0051444 [negative regulation of ubiquitin-protein transferase activity] GO:0055105 [ubiquitin-protein transferase inhibitor activity] GO:0070534 [protein K63-linked ubiquitination] GO:0071158 [positive regulation of cell cycle arrest] GO:0090398 [cellular senescence] GO:0097371 [MDM2/MDM4 family protein binding] GO:0097718 [disordered domain specific binding] GO:1900182 [positive regulation of protein localization to nucleus] GO:1901798 [positive regulation of signal transduction by p53 class mediator] GO:1902510 [regulation of apoptotic DNA fragmentation] GO:1904667 [negative regulation of ubiquitin protein ligase activity] GO:1990000 [amyloid fibril formation] GO:1990948 [ubiquitin ligase inhibitor activity] GO:2000059 [negative regulation of ubiquitin-dependent protein catabolic process] GO:2000435 [negative regulation of protein neddylation]
Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Disease related genes Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000082 [G1/S transition of mitotic cell cycle] GO:0001953 [negative regulation of cell-matrix adhesion] GO:0003723 [RNA binding] GO:0004861 [cyclin-dependent protein serine/threonine kinase inhibitor activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0007265 [Ras protein signal transduction] GO:0008285 [negative regulation of cell population proliferation] GO:0019901 [protein kinase binding] GO:0030308 [negative regulation of cell growth] GO:0032088 [negative regulation of NF-kappaB transcription factor activity] GO:0034393 [positive regulation of smooth muscle cell apoptotic process] GO:0035985 [senescence-associated heterochromatin focus] GO:0035986 [senescence-associated heterochromatin focus assembly] GO:0042326 [negative regulation of phosphorylation] GO:0045736 [negative regulation of cyclin-dependent protein serine/threonine kinase activity] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0051059 [NF-kappaB binding] GO:0090398 [cellular senescence] GO:0090399 [replicative senescence] GO:2000111 [positive regulation of macrophage apoptotic process] GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle] GO:2000774 [positive regulation of cellular senescence]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Protein evidence (Ezkurdia et al 2014)
Phobius predicted membrane proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Splicing Mutations COSMIC Somatic Mutations COSMIC Nonsense Mutations COSMIC Missense Mutations COSMIC Large Deletions COSMIC Germline Mutations COSMIC Frameshift Mutations Human disease related genes Cancers Head and neck cancers Cancers of the digestive system Cancers of the lung and pleura Skin cancers Cancers of soft tissues and bone Cancers of male genital organs Cancers of the urinary system Cancers of eye, brain, and central nervous system Cancers of haematopoietic and lymphoid tissues Endocrine and metabolic diseases Diabetes Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination] GO:0002039 [p53 binding] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005739 [mitochondrion] GO:0006364 [rRNA processing] GO:0006469 [negative regulation of protein kinase activity] GO:0006915 [apoptotic process] GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0007049 [cell cycle] GO:0007050 [cell cycle arrest] GO:0008134 [transcription factor binding] GO:0008285 [negative regulation of cell population proliferation] GO:0008637 [apoptotic mitochondrial changes] GO:0010389 [regulation of G2/M transition of mitotic cell cycle] GO:0010628 [positive regulation of gene expression] GO:0016604 [nuclear body] GO:0016925 [protein sumoylation] GO:0019789 [SUMO transferase activity] GO:0030889 [negative regulation of B cell proliferation] GO:0031647 [regulation of protein stability] GO:0031648 [protein destabilization] GO:0032991 [protein-containing complex] GO:0033088 [negative regulation of immature T cell proliferation in thymus] GO:0033235 [positive regulation of protein sumoylation] GO:0043065 [positive regulation of apoptotic process] GO:0043517 [positive regulation of DNA damage response, signal transduction by p53 class mediator] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0045944 [positive regulation of transcription by RNA polymerase II] GO:0046825 [regulation of protein export from nucleus] GO:0048103 [somatic stem cell division] GO:0050821 [protein stabilization] GO:0051444 [negative regulation of ubiquitin-protein transferase activity] GO:0055105 [ubiquitin-protein transferase inhibitor activity] GO:0070534 [protein K63-linked ubiquitination] GO:0071158 [positive regulation of cell cycle arrest] GO:0090398 [cellular senescence] GO:0097371 [MDM2/MDM4 family protein binding] GO:0097718 [disordered domain specific binding] GO:1900182 [positive regulation of protein localization to nucleus] GO:1901798 [positive regulation of signal transduction by p53 class mediator] GO:1902510 [regulation of apoptotic DNA fragmentation] GO:1904667 [negative regulation of ubiquitin protein ligase activity] GO:1990000 [amyloid fibril formation] GO:1990948 [ubiquitin ligase inhibitor activity] GO:2000059 [negative regulation of ubiquitin-dependent protein catabolic process] GO:2000435 [negative regulation of protein neddylation]
The Human Protein Atlas project is funded
