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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:218.9 nTPM
HPA:218.9 nTPM
GTEx:116.8 nTPM
FANTOM5:380.6 Scaled Tags Per Million
Pig:234.3 nTPM
Mouse:212.7 nTPM
Allen mouse:10.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 218.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 134.3
2586 Male, age 75, left hemisphere 228.7
2828 Female, age 72, unknown 186.9
1827 Male, age 72, unknown 164.6
1870 Female, age 42, unknown 133.8
2666 Male, age 74, left hemisphere 122.9
2411 Female, age 72, unknown 120.3
1833 Male, age 53, unknown 118.1
2219 Male, age 76, both hemispheres 99.6
1830 Male, age 51, unknown 98.4
2019 Male, age 18, unknown 69.9
Dorsal raphe nucleus
nTPM: 178.5
2016 Female, age 72, unknown 208.1
2047 Male, age 72, unknown 198.5
2298 Female, age 72, unknown 196.2
1828 Male, age 53, unknown 178.2
2750 Male, age 76, both hemispheres 111.7
Inferior colliculus
nTPM: 188.6
1848 Female, age 42, unknown 220.5
2849 Male, age 72, unknown 200.8
2097 Female, age 72, unknown 172.7
1890 Male, age 53, unknown 160.6
Median raphe nucleus
nTPM: 131.9
2220 Male, age 76, midline 131.9
Pedunculopontine tegmental nucleus
nTPM: 117.2
2334 Male, age 80, both hemispheres 144.3
1921 Female, age 85, both hemispheres 136.3
2338 Male, age 61, both hemispheres 71.1
Periaquaductal grey, anterior
nTPM: 195.8
1795 Male, age 51, unknown 201.9
1947 Male, age 18, unknown 198.0
2502 Female, age 75, unknown 187.4
Periaquaductal grey, dorsal
nTPM: 218.9
1840 Male, age 53, unknown 284.8
2850 Male, age 76, both hemispheres 233.8
2464 Female, age 72, unknown 194.7
1831 Male, age 72, unknown 162.4
Periaquaductal grey, lateral
nTPM: 183.7
2053 Male, age 18, unknown 220.6
2140 Male, age 76, both hemispheres 207.8
2272 Male, age 74, both hemispheres 122.6
Pretectal area
nTPM: 170.7
2667 Female, age 75, unknown 211.8
1944 Female, age 72, unknown 193.0
1816 Male, age 51, unknown 189.5
2825 Male, age 18, unknown 187.4
2273 Male, age 74, both hemispheres 184.1
2224 Female, age 72, unknown 182.4
1817 Female, age 42, unknown 175.4
1815 Male, age 53, unknown 156.1
2407 Male, age 75, both hemispheres 151.3
2316 Male, age 76, right hemisphere 138.6
2007 Male, age 72, unknown 108.1
Red nucleus
nTPM: 117.5
1954 Female, age 42, unknown 148.3
2725 Female, age 75, unknown 140.8
2503 Female, age 72, unknown 136.0
1821 Female, age 72, unknown 131.9
2227 Male, age 72, unknown 126.9
2769 Male, age 72, unknown 125.8
2588 Male, age 74, left hemisphere 119.4
1904 Male, age 53, unknown 112.5
1865 Male, age 51, unknown 107.5
2823 Male, age 76, right hemisphere 96.5
2584 Male, age 75, left hemisphere 92.0
2785 Male, age 18, unknown 72.9
Substantia nigra
nTPM: 142.5
2699 Male, age 18, unknown 226.8
1916 Female, age 42, unknown 169.7
1889 Female, age 72, unknown 156.3
2241 Male, age 72, unknown 142.8
1851 Male, age 51, unknown 134.8
2665 Male, age 74, both hemispheres 132.3
2583 Male, age 75, right hemisphere 122.0
2409 Female, age 72, unknown 113.6
1941 Male, age 53, unknown 113.4
2590 Female, age 75, unknown 113.3
Superior colliculus
nTPM: 166.2
2664 Male, age 75, both hemispheres 229.2
2261 Male, age 18, unknown 190.0
2087 Female, age 72, unknown 184.6
1796 Male, age 53, unknown 181.9
1995 Male, age 72, unknown 177.1
1839 Male, age 51, unknown 171.4
2587 Male, age 74, left hemisphere 143.6
1913 Female, age 42, unknown 142.5
2668 Female, age 75, unknown 136.4
1895 Male, age 76, right hemisphere 104.9
Ventral tegmental area
nTPM: 136.5
1942 Male, age 51, unknown 159.0
2021 Male, age 53, unknown 152.9
2410 Female, age 72, unknown 135.3
1915 Female, age 42, unknown 130.4
2218 Male, age 76, both hemispheres 126.8
2223 Female, age 72, unknown 114.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 116.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 116.8
Samples: 139

Max nTPM: 417.8
Min nTPM: 19.7
Std nTPM: 66.5
Median nTPM: 103.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 417.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 354.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 300.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 292.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 274.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 268.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 237.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 232.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 229.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 228.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 221.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 217.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 205.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 200.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 200.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 198.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 194.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 193.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 190.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 189.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 189.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 177.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 175.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 171.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 169.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 169.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 167.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 166.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 164.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 160.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 158.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 158.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 157.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 150.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 149.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 142.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 139.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 138.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 138.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 133.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 132.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 131.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 130.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 128.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 127.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 123.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 122.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 120.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 117.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 117.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 116.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 116.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 115.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 114.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 113.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 112.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 111.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 111.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 110.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 110.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 110.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 108.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 106.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 106.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 106.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 106.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 105.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 105.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 105.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 103.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 101.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 99.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 99.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 97.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 97.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 96.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 96.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 94.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 94.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 93.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 91.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 88.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 87.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 87.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 87.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 86.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 86.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 85.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 85.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 85.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 84.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 83.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 83.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 82.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 80.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 78.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 78.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 77.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 77.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 76.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 76.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 73.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 73.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 72.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 71.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 71.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 71.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 70.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 69.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 68.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 67.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 67.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 66.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 65.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 65.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 64.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 61.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 61.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 60.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 52.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 51.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 51.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 49.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 48.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 48.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 47.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 47.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 45.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 44.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 44.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 41.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 38.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 37.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 37.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 35.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 27.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 23.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 23.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 19.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 380.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 380.6
FF:10158-103A5 76 years, female 380.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 234.3
Pig sample Sample description nTPM
Midbrain
nTPM: 234.3
Samples: 4

Max nTPM: 305.9
Min nTPM: 189.5
Sample A Female 305.9
Sample B Female 193.6
Sample C Male 248.1
Sample D Male 189.5
Periaqueductal gray
nTPM: 212.1
Samples: 3

Max nTPM: 235.1
Min nTPM: 181.5
Sample B Female 219.6
Sample C Male 235.1
Sample D Male 181.5
Substantia nigra
nTPM: 180.9
Samples: 4

Max nTPM: 200.8
Min nTPM: 160.9
Sample A Female 195.0
Sample B Female 166.9
Sample C Male 200.8
Sample D Male 160.9
Superior colliculi
nTPM: 154.6
Samples: 4

Max nTPM: 183.1
Min nTPM: 93.9
Sample A Female 158.8
Sample B Female 93.9
Sample C Male 183.1
Sample D Male 182.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 212.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 212.7
Samples: 4

Max nTPM: 223.4
Min nTPM: 203.7
Sample A Male 203.7
Sample B Male 208.6
Sample C Female 215.2
Sample D Female 223.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.9
79360318 Antisense, RP_071018_02_A09, Mouse strain C57BL/6J (56 days, male) 13.9
747 Antisense, RP_Baylor_253946, Mouse strain C57BL/6J (56 days, male) 7.9
746 Antisense, RP_Baylor_253946, Mouse strain C57BL/6J (56 days, male) 2.8

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