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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:284.6 nTPM
HPA:284.6 nTPM
GTEx:306.4 nTPM
FANTOM5:541.2 Scaled Tags Per Million
Pig:129.1 nTPM
Mouse:128.1 nTPM
Allen mouse:6.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 284.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 233.3
2019 Male, age 18, unknown 296.9
1870 Female, age 42, unknown 278.3
2411 Female, age 72, unknown 277.9
1830 Male, age 51, unknown 275.4
1833 Male, age 53, unknown 252.5
2828 Female, age 72, unknown 234.2
2586 Male, age 75, left hemisphere 210.1
1827 Male, age 72, unknown 178.1
2219 Male, age 76, both hemispheres 166.4
2666 Male, age 74, left hemisphere 163.1
Dorsal raphe nucleus
nTPM: 189.8
2750 Male, age 76, both hemispheres 268.7
2016 Female, age 72, unknown 194.3
1828 Male, age 53, unknown 187.8
2047 Male, age 72, unknown 150.9
2298 Female, age 72, unknown 147.4
Inferior colliculus
nTPM: 168.1
1890 Male, age 53, unknown 186.7
1848 Female, age 42, unknown 179.1
2097 Female, age 72, unknown 153.9
2849 Male, age 72, unknown 152.8
Median raphe nucleus
nTPM: 197.6
2220 Male, age 76, midline 197.6
Pedunculopontine tegmental nucleus
nTPM: 231.2
2338 Male, age 61, both hemispheres 295.1
2334 Male, age 80, both hemispheres 229.5
1921 Female, age 85, both hemispheres 169.0
Periaquaductal grey, anterior
nTPM: 167.3
2502 Female, age 75, unknown 183.4
1795 Male, age 51, unknown 162.0
1947 Male, age 18, unknown 156.4
Periaquaductal grey, dorsal
nTPM: 164.4
2850 Male, age 76, both hemispheres 197.9
2464 Female, age 72, unknown 179.4
1831 Male, age 72, unknown 162.9
1840 Male, age 53, unknown 117.2
Periaquaductal grey, lateral
nTPM: 201.0
2140 Male, age 76, both hemispheres 224.8
2272 Male, age 74, both hemispheres 197.2
2053 Male, age 18, unknown 180.9
Pretectal area
nTPM: 180.7
2316 Male, age 76, right hemisphere 230.0
2273 Male, age 74, both hemispheres 226.1
2667 Female, age 75, unknown 210.2
1815 Male, age 53, unknown 202.0
2407 Male, age 75, both hemispheres 191.6
1817 Female, age 42, unknown 182.1
2825 Male, age 18, unknown 173.1
2007 Male, age 72, unknown 169.0
2224 Female, age 72, unknown 158.3
1944 Female, age 72, unknown 130.5
1816 Male, age 51, unknown 115.4
Red nucleus
nTPM: 284.6
2769 Male, age 72, unknown 338.6
2227 Male, age 72, unknown 337.7
1904 Male, age 53, unknown 337.6
1865 Male, age 51, unknown 333.6
2785 Male, age 18, unknown 322.6
1954 Female, age 42, unknown 312.8
1821 Female, age 72, unknown 297.5
2503 Female, age 72, unknown 276.4
2823 Male, age 76, right hemisphere 264.8
2588 Male, age 74, left hemisphere 204.9
2584 Male, age 75, left hemisphere 199.1
2725 Female, age 75, unknown 190.0
Substantia nigra
nTPM: 196.7
1851 Male, age 51, unknown 237.3
2583 Male, age 75, right hemisphere 235.1
2590 Female, age 75, unknown 226.4
2409 Female, age 72, unknown 218.3
2699 Male, age 18, unknown 211.0
1889 Female, age 72, unknown 179.2
1916 Female, age 42, unknown 176.2
1941 Male, age 53, unknown 170.8
2241 Male, age 72, unknown 160.9
2665 Male, age 74, both hemispheres 152.0
Superior colliculus
nTPM: 192.3
1995 Male, age 72, unknown 281.4
1913 Female, age 42, unknown 260.1
2587 Male, age 74, left hemisphere 214.9
1839 Male, age 51, unknown 193.0
1796 Male, age 53, unknown 178.4
2668 Female, age 75, unknown 175.4
1895 Male, age 76, right hemisphere 163.5
2664 Male, age 75, both hemispheres 158.6
2087 Female, age 72, unknown 155.8
2261 Male, age 18, unknown 141.5
Ventral tegmental area
nTPM: 233.7
2223 Female, age 72, unknown 316.2
2410 Female, age 72, unknown 244.7
2021 Male, age 53, unknown 223.1
1942 Male, age 51, unknown 209.8
1915 Female, age 42, unknown 206.4
2218 Male, age 76, both hemispheres 201.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 306.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 306.4
Samples: 139

Max nTPM: 889.3
Min nTPM: 94.8
Std nTPM: 120.4
Median nTPM: 273.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 889.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 757.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 658.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 634.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 594.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 578.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 550.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 548.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 531.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 489.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 483.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 479.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 478.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 471.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 467.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 460.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 449.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 447.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 417.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 409.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 409.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 402.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 387.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 386.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 380.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 376.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 373.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 371.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 370.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 365.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 362.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 356.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 354.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 352.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 352.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 346.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 344.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 344.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 340.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 340.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 335.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 335.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 334.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 333.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 323.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 323.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 319.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 315.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 315.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 314.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 313.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 308.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 308.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 307.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 307.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 304.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 304.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 299.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 297.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 288.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 288.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 286.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 281.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 280.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 279.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 277.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 276.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 276.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 274.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 273.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 269.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 268.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 266.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 266.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 265.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 264.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 264.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 260.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 259.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 258.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 257.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 257.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 255.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 254.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 253.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 252.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 252.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 252.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 250.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 250.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 250.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 249.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 246.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 242.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 240.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 238.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 237.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 237.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 236.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 234.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 233.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 232.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 230.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 225.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 223.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 222.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 221.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 221.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 220.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 219.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 219.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 218.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 216.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 215.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 214.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 213.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 212.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 208.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 208.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 207.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 205.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 204.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 203.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 198.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 198.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 192.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 192.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 191.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 191.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 189.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 187.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 187.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 182.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 176.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 173.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 163.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 148.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 129.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 94.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 541.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 541.2
FF:10158-103A5 76 years, female 541.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 129.1
Pig sample Sample description nTPM
Midbrain
nTPM: 124.5
Samples: 4

Max nTPM: 319.9
Min nTPM: 42.5
Sample A Female 319.9
Sample B Female 71.8
Sample C Male 63.9
Sample D Male 42.5
Periaqueductal gray
nTPM: 79.7
Samples: 3

Max nTPM: 90.3
Min nTPM: 69.4
Sample B Female 69.4
Sample C Male 79.3
Sample D Male 90.3
Substantia nigra
nTPM: 122.1
Samples: 4

Max nTPM: 152.7
Min nTPM: 86.7
Sample A Female 102.8
Sample B Female 152.7
Sample C Male 86.7
Sample D Male 146.0
Superior colliculi
nTPM: 129.1
Samples: 4

Max nTPM: 218.9
Min nTPM: 87.9
Sample A Female 120.8
Sample B Female 218.9
Sample C Male 87.9
Sample D Male 88.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 128.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 128.1
Samples: 4

Max nTPM: 150.1
Min nTPM: 108.7
Sample A Male 118.2
Sample B Male 108.7
Sample C Female 135.4
Sample D Female 150.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.0
72081395 Antisense, RP_051017_01_C01, Mouse strain C57BL/6J (56 days, male) 9.8
68444642 Antisense, RP_050111_02_C03, Mouse strain C57BL/6J (56 days, male) 2.2

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