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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:71.1 nTPM
HPA:71.1 nTPM
GTEx:78.2 nTPM
FANTOM5:72.8 Scaled Tags Per Million
Pig:50.6 nTPM
Mouse:89.9 nTPM
Allen mouse:4.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 71.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 71.1
2586 Male, age 75, left hemisphere 78.2
2411 Female, age 72, unknown 74.0
2666 Male, age 74, left hemisphere 72.6
1827 Male, age 72, unknown 71.6
2019 Male, age 18, unknown 70.6
2828 Female, age 72, unknown 70.5
2219 Male, age 76, both hemispheres 70.2
1870 Female, age 42, unknown 69.3
1833 Male, age 53, unknown 67.5
1830 Male, age 51, unknown 66.5
Dorsal raphe nucleus
nTPM: 64.2
2750 Male, age 76, both hemispheres 71.4
1828 Male, age 53, unknown 63.8
2047 Male, age 72, unknown 63.2
2298 Female, age 72, unknown 62.8
2016 Female, age 72, unknown 60.0
Inferior colliculus
nTPM: 61.6
2849 Male, age 72, unknown 64.1
1848 Female, age 42, unknown 62.6
1890 Male, age 53, unknown 60.1
2097 Female, age 72, unknown 59.6
Median raphe nucleus
nTPM: 66.7
2220 Male, age 76, midline 66.7
Pedunculopontine tegmental nucleus
nTPM: 69.2
2334 Male, age 80, both hemispheres 71.9
1921 Female, age 85, both hemispheres 68.6
2338 Male, age 61, both hemispheres 67.2
Periaquaductal grey, anterior
nTPM: 68.1
1795 Male, age 51, unknown 72.4
1947 Male, age 18, unknown 68.3
2502 Female, age 75, unknown 63.4
Periaquaductal grey, dorsal
nTPM: 61.3
2464 Female, age 72, unknown 63.0
1831 Male, age 72, unknown 62.4
1840 Male, age 53, unknown 61.8
2850 Male, age 76, both hemispheres 58.1
Periaquaductal grey, lateral
nTPM: 60.3
2053 Male, age 18, unknown 63.1
2272 Male, age 74, both hemispheres 60.7
2140 Male, age 76, both hemispheres 57.3
Pretectal area
nTPM: 70.8
2007 Male, age 72, unknown 81.6
1816 Male, age 51, unknown 79.1
1817 Female, age 42, unknown 78.6
1944 Female, age 72, unknown 77.8
1815 Male, age 53, unknown 73.6
2407 Male, age 75, both hemispheres 70.5
2667 Female, age 75, unknown 69.4
2825 Male, age 18, unknown 64.5
2224 Female, age 72, unknown 63.5
2316 Male, age 76, right hemisphere 61.8
2273 Male, age 74, both hemispheres 58.4
Red nucleus
nTPM: 67.4
2584 Male, age 75, left hemisphere 77.5
2785 Male, age 18, unknown 76.4
2588 Male, age 74, left hemisphere 74.5
2503 Female, age 72, unknown 68.2
2769 Male, age 72, unknown 66.9
2823 Male, age 76, right hemisphere 66.4
2227 Male, age 72, unknown 65.5
1865 Male, age 51, unknown 64.4
1821 Female, age 72, unknown 63.7
1904 Male, age 53, unknown 63.7
1954 Female, age 42, unknown 63.1
2725 Female, age 75, unknown 58.4
Substantia nigra
nTPM: 64.8
2583 Male, age 75, right hemisphere 76.0
1889 Female, age 72, unknown 71.8
2665 Male, age 74, both hemispheres 69.5
1941 Male, age 53, unknown 68.8
1851 Male, age 51, unknown 64.9
1916 Female, age 42, unknown 62.4
2590 Female, age 75, unknown 60.6
2699 Male, age 18, unknown 59.4
2409 Female, age 72, unknown 58.3
2241 Male, age 72, unknown 55.8
Superior colliculus
nTPM: 70.3
2668 Female, age 75, unknown 97.5
1796 Male, age 53, unknown 72.0
1913 Female, age 42, unknown 71.7
2087 Female, age 72, unknown 70.9
2261 Male, age 18, unknown 68.4
1995 Male, age 72, unknown 68.3
1839 Male, age 51, unknown 65.6
2664 Male, age 75, both hemispheres 63.2
2587 Male, age 74, left hemisphere 63.1
1895 Male, age 76, right hemisphere 62.0
Ventral tegmental area
nTPM: 65.6
2223 Female, age 72, unknown 73.4
2410 Female, age 72, unknown 65.9
2218 Male, age 76, both hemispheres 63.9
1915 Female, age 42, unknown 63.7
1942 Male, age 51, unknown 63.5
2021 Male, age 53, unknown 63.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 78.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 78.2
Samples: 139

Max nTPM: 199.8
Min nTPM: 28.2
Std nTPM: 25.1
Median nTPM: 75.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 199.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 173.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 143.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 141.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 137.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 131.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 124.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 121.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 116.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 113.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 111.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 104.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 103.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 101.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 100.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 100.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 99.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 98.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 98.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 97.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 97.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 96.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 96.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 96.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 95.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 95.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 94.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 93.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 93.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 92.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 92.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 92.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 91.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 91.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 90.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 90.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 90.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 89.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 89.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 88.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 88.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 87.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 87.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 86.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 85.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 85.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 84.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 84.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 84.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 83.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 83.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 83.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 82.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 82.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 82.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 82.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 82.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 80.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 80.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 79.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 79.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 79.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 78.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 77.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 76.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 76.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 76.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 75.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 75.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 74.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 73.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 73.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 73.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 73.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 73.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 72.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 72.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 72.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 72.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 71.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 71.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 71.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 71.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 71.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 70.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 69.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 69.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 69.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 69.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 68.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 67.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 67.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 66.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 66.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 66.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 66.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 66.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 64.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 63.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 63.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 62.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 61.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 61.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 60.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 59.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 58.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 58.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 58.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 57.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 57.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 57.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 56.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 55.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 55.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 54.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 53.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 52.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 51.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 50.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 50.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 50.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 50.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 50.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 50.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 50.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 45.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 44.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 42.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 42.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 41.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 39.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 39.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 37.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 36.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 28.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 72.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 72.8
FF:10158-103A5 76 years, female 72.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 50.6
Pig sample Sample description nTPM
Midbrain
nTPM: 50.6
Samples: 4

Max nTPM: 83.4
Min nTPM: 36.2
Sample A Female 83.4
Sample B Female 45.5
Sample C Male 36.2
Sample D Male 37.2
Periaqueductal gray
nTPM: 36.7
Samples: 3

Max nTPM: 41.1
Min nTPM: 32.8
Sample B Female 36.2
Sample C Male 41.1
Sample D Male 32.8
Substantia nigra
nTPM: 46.5
Samples: 4

Max nTPM: 55.2
Min nTPM: 34.5
Sample A Female 55.2
Sample B Female 34.5
Sample C Male 46.3
Sample D Male 49.9
Superior colliculi
nTPM: 39.9
Samples: 4

Max nTPM: 45.7
Min nTPM: 30.1
Sample A Female 45.7
Sample B Female 30.1
Sample C Male 40.5
Sample D Male 43.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 89.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 89.9
Samples: 4

Max nTPM: 95.5
Min nTPM: 84.3
Sample A Male 95.5
Sample B Male 86.0
Sample C Female 84.3
Sample D Female 93.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.3
69549263 Antisense, RP_050126_01_E06, Mouse strain C57BL/6J (56 days, male) 4.3

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