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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:94.8 nTPM
HPA:94.8 nTPM
GTEx:72.6 nTPM
FANTOM5:275.4 Scaled Tags Per Million
Pig:112.6 nTPM
Mouse:57.4 nTPM
Allen mouse:1.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 94.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 83.3
2828 Female, age 72, unknown 93.9
1870 Female, age 42, unknown 88.9
1827 Male, age 72, unknown 85.8
2586 Male, age 75, left hemisphere 84.6
1833 Male, age 53, unknown 82.8
1830 Male, age 51, unknown 82.4
2019 Male, age 18, unknown 81.3
2411 Female, age 72, unknown 79.4
2666 Male, age 74, left hemisphere 77.2
2219 Male, age 76, both hemispheres 77.1
Dorsal raphe nucleus
nTPM: 89.4
2016 Female, age 72, unknown 107.2
2298 Female, age 72, unknown 89.9
1828 Male, age 53, unknown 88.9
2047 Male, age 72, unknown 81.1
2750 Male, age 76, both hemispheres 79.7
Inferior colliculus
nTPM: 88.2
2097 Female, age 72, unknown 91.4
1848 Female, age 42, unknown 89.9
2849 Male, age 72, unknown 87.3
1890 Male, age 53, unknown 84.2
Median raphe nucleus
nTPM: 74.4
2220 Male, age 76, midline 74.4
Pedunculopontine tegmental nucleus
nTPM: 80.7
2334 Male, age 80, both hemispheres 81.7
1921 Female, age 85, both hemispheres 81.4
2338 Male, age 61, both hemispheres 79.0
Periaquaductal grey, anterior
nTPM: 86.1
1795 Male, age 51, unknown 87.4
1947 Male, age 18, unknown 86.2
2502 Female, age 75, unknown 84.7
Periaquaductal grey, dorsal
nTPM: 94.8
2850 Male, age 76, both hemispheres 99.8
1840 Male, age 53, unknown 96.8
1831 Male, age 72, unknown 93.9
2464 Female, age 72, unknown 88.7
Periaquaductal grey, lateral
nTPM: 89.7
2053 Male, age 18, unknown 94.9
2140 Male, age 76, both hemispheres 93.0
2272 Male, age 74, both hemispheres 81.2
Pretectal area
nTPM: 88.9
2273 Male, age 74, both hemispheres 101.6
1815 Male, age 53, unknown 92.7
2407 Male, age 75, both hemispheres 92.0
2224 Female, age 72, unknown 90.3
2316 Male, age 76, right hemisphere 90.2
1944 Female, age 72, unknown 89.7
2825 Male, age 18, unknown 86.1
1816 Male, age 51, unknown 85.8
2667 Female, age 75, unknown 85.8
1817 Female, age 42, unknown 85.6
2007 Male, age 72, unknown 78.3
Red nucleus
nTPM: 83.4
2503 Female, age 72, unknown 91.3
1904 Male, age 53, unknown 89.8
1954 Female, age 42, unknown 88.2
1821 Female, age 72, unknown 87.3
1865 Male, age 51, unknown 85.3
2769 Male, age 72, unknown 85.0
2227 Male, age 72, unknown 84.4
2823 Male, age 76, right hemisphere 83.9
2785 Male, age 18, unknown 81.5
2725 Female, age 75, unknown 80.1
2588 Male, age 74, left hemisphere 74.3
2584 Male, age 75, left hemisphere 69.4
Substantia nigra
nTPM: 85.1
2699 Male, age 18, unknown 96.1
2409 Female, age 72, unknown 92.0
2590 Female, age 75, unknown 90.6
1889 Female, age 72, unknown 88.0
2583 Male, age 75, right hemisphere 86.3
1851 Male, age 51, unknown 84.5
2241 Male, age 72, unknown 81.7
2665 Male, age 74, both hemispheres 81.1
1941 Male, age 53, unknown 77.6
1916 Female, age 42, unknown 73.5
Superior colliculus
nTPM: 93.8
1995 Male, age 72, unknown 115.7
1913 Female, age 42, unknown 103.5
2664 Male, age 75, both hemispheres 96.9
2668 Female, age 75, unknown 94.9
2587 Male, age 74, left hemisphere 94.5
2087 Female, age 72, unknown 90.6
1839 Male, age 51, unknown 89.6
1796 Male, age 53, unknown 85.8
1895 Male, age 76, right hemisphere 83.6
2261 Male, age 18, unknown 83.0
Ventral tegmental area
nTPM: 84.5
2021 Male, age 53, unknown 90.7
1942 Male, age 51, unknown 87.2
1915 Female, age 42, unknown 85.3
2223 Female, age 72, unknown 84.7
2410 Female, age 72, unknown 83.0
2218 Male, age 76, both hemispheres 76.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 72.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.6
Samples: 139

Max nTPM: 154.3
Min nTPM: 26.8
Std nTPM: 26.6
Median nTPM: 69.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 154.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 144.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 143.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 129.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 129.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 126.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 125.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 124.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 118.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 116.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 116.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 112.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 112.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 109.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 108.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 106.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 105.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 100.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 98.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 98.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 97.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 97.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 96.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 96.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 95.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 95.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 95.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 95.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 94.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 93.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 92.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 91.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 91.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 91.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 90.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 89.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 89.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 89.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 89.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 87.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 86.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 86.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 85.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 85.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 84.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 83.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 81.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 80.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 80.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 80.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 79.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 79.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 79.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 78.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 78.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 77.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 77.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 77.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 75.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 75.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 73.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 73.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 73.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 72.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 71.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 71.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 71.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 69.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 69.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 69.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 66.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 66.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 66.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 65.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 65.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 64.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 63.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 63.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 63.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 63.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 63.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 63.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 62.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 62.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 61.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 61.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 61.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 60.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 60.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 59.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 59.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 56.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 56.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 56.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 56.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 54.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 54.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 54.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 52.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 52.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 51.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 50.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 49.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 49.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 49.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 49.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 48.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 47.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 47.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 47.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 47.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 46.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 45.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 45.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 45.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 43.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 43.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 43.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 42.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 40.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 40.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 37.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 37.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 37.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 37.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 35.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 35.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 35.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 34.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 33.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 33.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 33.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 30.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 29.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 26.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 275.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 275.4
FF:10158-103A5 76 years, female 275.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 112.6
Pig sample Sample description nTPM
Midbrain
nTPM: 112.6
Samples: 4

Max nTPM: 159.4
Min nTPM: 79.5
Sample A Female 159.4
Sample B Female 101.9
Sample C Male 109.5
Sample D Male 79.5
Periaqueductal gray
nTPM: 89.8
Samples: 3

Max nTPM: 97.9
Min nTPM: 78.5
Sample B Female 93.1
Sample C Male 78.5
Sample D Male 97.9
Substantia nigra
nTPM: 96.0
Samples: 4

Max nTPM: 107.9
Min nTPM: 84.7
Sample A Female 102.6
Sample B Female 84.7
Sample C Male 88.9
Sample D Male 107.9
Superior colliculi
nTPM: 107.8
Samples: 4

Max nTPM: 121.5
Min nTPM: 99.1
Sample A Female 99.1
Sample B Female 121.5
Sample C Male 106.8
Sample D Male 103.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 57.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 57.4
Samples: 4

Max nTPM: 60.7
Min nTPM: 53.4
Sample A Male 60.7
Sample B Male 58.1
Sample C Female 57.2
Sample D Female 53.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.6
68795422 Antisense, RP_041122_02_E04, Mouse strain C57BL/6J (56 days, male) 1.6

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