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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:127.1 nTPM
HPA:127.1 nTPM
GTEx:107.3 nTPM
FANTOM5:51.0 Scaled Tags Per Million
Pig:19.6 nTPM
Mouse:37.4 nTPM
Allen mouse:0.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 127.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 116.7
2411 Female, age 72, unknown 127.2
1827 Male, age 72, unknown 122.8
1870 Female, age 42, unknown 119.1
2019 Male, age 18, unknown 116.4
1833 Male, age 53, unknown 115.1
1830 Male, age 51, unknown 114.6
2828 Female, age 72, unknown 114.6
2666 Male, age 74, left hemisphere 114.4
2219 Male, age 76, both hemispheres 111.9
2586 Male, age 75, left hemisphere 110.9
Dorsal raphe nucleus
nTPM: 118.6
2298 Female, age 72, unknown 124.7
2750 Male, age 76, both hemispheres 121.1
1828 Male, age 53, unknown 118.3
2047 Male, age 72, unknown 117.6
2016 Female, age 72, unknown 111.4
Inferior colliculus
nTPM: 116.3
2097 Female, age 72, unknown 121.6
1890 Male, age 53, unknown 117.8
1848 Female, age 42, unknown 115.2
2849 Male, age 72, unknown 110.8
Median raphe nucleus
nTPM: 118.3
2220 Male, age 76, midline 118.3
Pedunculopontine tegmental nucleus
nTPM: 118.5
2334 Male, age 80, both hemispheres 120.4
1921 Female, age 85, both hemispheres 118.8
2338 Male, age 61, both hemispheres 116.3
Periaquaductal grey, anterior
nTPM: 127.1
1947 Male, age 18, unknown 142.7
2502 Female, age 75, unknown 119.6
1795 Male, age 51, unknown 119.0
Periaquaductal grey, dorsal
nTPM: 111.5
2464 Female, age 72, unknown 113.1
1840 Male, age 53, unknown 112.4
2850 Male, age 76, both hemispheres 110.6
1831 Male, age 72, unknown 110.0
Periaquaductal grey, lateral
nTPM: 113.4
2272 Male, age 74, both hemispheres 117.2
2053 Male, age 18, unknown 111.9
2140 Male, age 76, both hemispheres 111.0
Pretectal area
nTPM: 117.6
1816 Male, age 51, unknown 122.9
1944 Female, age 72, unknown 120.0
2007 Male, age 72, unknown 119.3
1817 Female, age 42, unknown 119.0
2667 Female, age 75, unknown 118.8
1815 Male, age 53, unknown 118.4
2273 Male, age 74, both hemispheres 117.4
2224 Female, age 72, unknown 117.0
2316 Male, age 76, right hemisphere 115.8
2825 Male, age 18, unknown 114.8
2407 Male, age 75, both hemispheres 110.0
Red nucleus
nTPM: 117.5
1821 Female, age 72, unknown 125.2
1865 Male, age 51, unknown 119.7
1904 Male, age 53, unknown 119.3
2725 Female, age 75, unknown 119.1
2503 Female, age 72, unknown 118.7
1954 Female, age 42, unknown 118.5
2823 Male, age 76, right hemisphere 117.7
2227 Male, age 72, unknown 116.2
2588 Male, age 74, left hemisphere 115.1
2769 Male, age 72, unknown 114.8
2785 Male, age 18, unknown 113.1
2584 Male, age 75, left hemisphere 112.3
Substantia nigra
nTPM: 120.2
2241 Male, age 72, unknown 128.0
1916 Female, age 42, unknown 125.7
1851 Male, age 51, unknown 125.2
2590 Female, age 75, unknown 122.3
2409 Female, age 72, unknown 121.9
1889 Female, age 72, unknown 121.0
1941 Male, age 53, unknown 116.1
2583 Male, age 75, right hemisphere 114.8
2665 Male, age 74, both hemispheres 114.8
2699 Male, age 18, unknown 112.5
Superior colliculus
nTPM: 116.1
2261 Male, age 18, unknown 121.5
1796 Male, age 53, unknown 121.1
1895 Male, age 76, right hemisphere 118.8
2087 Female, age 72, unknown 118.6
1913 Female, age 42, unknown 116.9
2668 Female, age 75, unknown 115.6
2587 Male, age 74, left hemisphere 114.0
1995 Male, age 72, unknown 113.7
1839 Male, age 51, unknown 112.8
2664 Male, age 75, both hemispheres 107.7
Ventral tegmental area
nTPM: 118.5
2410 Female, age 72, unknown 124.8
1915 Female, age 42, unknown 123.6
1942 Male, age 51, unknown 117.2
2218 Male, age 76, both hemispheres 116.6
2223 Female, age 72, unknown 116.2
2021 Male, age 53, unknown 112.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 107.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 107.3
Samples: 139

Max nTPM: 221.8
Min nTPM: 61.1
Std nTPM: 25.8
Median nTPM: 102.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 221.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 198.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 191.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 187.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 174.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 154.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 153.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 151.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 149.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 144.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 143.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 142.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 138.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 136.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 136.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 136.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 136.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 134.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 133.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 132.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 129.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 129.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 128.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 128.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 127.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 126.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 126.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 124.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 124.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 123.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 122.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 122.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 120.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 120.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 120.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 120.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 117.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 116.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 116.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 115.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 115.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 114.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 114.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 113.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 113.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 113.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 112.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 111.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 111.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 110.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 110.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 109.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 109.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 108.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 107.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 107.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 107.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 105.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 104.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 104.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 104.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 104.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 104.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 104.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 103.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 102.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 102.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 102.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 102.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 102.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 100.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 100.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 99.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 99.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 99.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 99.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 98.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 97.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 97.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 97.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 96.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 96.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 95.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 95.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 95.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 94.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 94.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 94.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 94.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 94.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 94.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 93.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 93.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 93.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 93.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 92.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 92.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 92.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 92.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 92.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 92.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 91.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 91.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 90.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 89.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 89.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 89.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 89.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 88.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 87.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 87.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 87.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 87.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 86.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 86.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 85.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 85.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 82.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 82.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 82.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 82.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 81.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 81.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 81.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 80.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 80.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 79.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 79.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 79.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 77.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 76.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 76.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 76.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 74.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 72.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 71.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 67.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 51.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 51.0
FF:10158-103A5 76 years, female 51.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 19.6
Pig sample Sample description nTPM
Midbrain
nTPM: 0.6
Samples: 4

Max nTPM: 0.7
Min nTPM: 0.4
Sample A Female 0.7
Sample B Female 0.5
Sample C Male 0.4
Sample D Male 0.7
Periaqueductal gray
nTPM: 0.8
Samples: 3

Max nTPM: 1.0
Min nTPM: 0.3
Sample B Female 0.3
Sample C Male 1.0
Sample D Male 1.0
Substantia nigra
nTPM: 1.0
Samples: 4

Max nTPM: 1.3
Min nTPM: 0.6
Sample A Female 1.1
Sample B Female 1.0
Sample C Male 1.3
Sample D Male 0.6
Superior colliculi
nTPM: 0.4
Samples: 4

Max nTPM: 0.7
Min nTPM: 0.2
Sample A Female 0.3
Sample B Female 0.7
Sample C Male 0.3
Sample D Male 0.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 37.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 37.4
Samples: 4

Max nTPM: 42.6
Min nTPM: 34.5
Sample A Male 34.5
Sample B Male 36.2
Sample C Female 36.3
Sample D Female 42.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.6
74511807 Antisense, RP_060220_03_B04, Mouse strain C57BL/6J (56 days, male) 0.7
71232779 Antisense, RP_050503_01_C10, Mouse strain C57BL/6J (56 days, male) 0.4

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