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LYPD1
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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:30.0 nTPM
HPA:30.0 nTPM
GTEx:54.2 nTPM
FANTOM5:10.3 Scaled Tags Per Million
Pig:7.8 nTPM
Mouse:59.7 nTPM
Allen mouse:4.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 30.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 22.7
2586 Male, age 75, left hemisphere 28.9
2219 Male, age 76, both hemispheres 27.9
1827 Male, age 72, unknown 26.6
1833 Male, age 53, unknown 23.2
2828 Female, age 72, unknown 22.5
1870 Female, age 42, unknown 22.0
2411 Female, age 72, unknown 21.7
1830 Male, age 51, unknown 20.6
2666 Male, age 74, left hemisphere 17.4
2019 Male, age 18, unknown 16.1
Dorsal raphe nucleus
nTPM: 28.1
2298 Female, age 72, unknown 32.2
2047 Male, age 72, unknown 29.7
2016 Female, age 72, unknown 29.4
1828 Male, age 53, unknown 27.2
2750 Male, age 76, both hemispheres 22.0
Inferior colliculus
nTPM: 23.5
2849 Male, age 72, unknown 25.3
1890 Male, age 53, unknown 24.7
2097 Female, age 72, unknown 23.8
1848 Female, age 42, unknown 20.2
Median raphe nucleus
nTPM: 21.1
2220 Male, age 76, midline 21.1
Pedunculopontine tegmental nucleus
nTPM: 23.5
2334 Male, age 80, both hemispheres 25.2
1921 Female, age 85, both hemispheres 23.6
2338 Male, age 61, both hemispheres 21.7
Periaquaductal grey, anterior
nTPM: 25.8
1795 Male, age 51, unknown 29.4
1947 Male, age 18, unknown 24.9
2502 Female, age 75, unknown 23.0
Periaquaductal grey, dorsal
nTPM: 29.4
2850 Male, age 76, both hemispheres 36.1
1840 Male, age 53, unknown 29.6
1831 Male, age 72, unknown 27.4
2464 Female, age 72, unknown 24.6
Periaquaductal grey, lateral
nTPM: 29.0
2272 Male, age 74, both hemispheres 33.6
2140 Male, age 76, both hemispheres 29.5
2053 Male, age 18, unknown 23.9
Pretectal area
nTPM: 21.8
2224 Female, age 72, unknown 34.0
2825 Male, age 18, unknown 29.0
2007 Male, age 72, unknown 23.9
2273 Male, age 74, both hemispheres 23.9
1816 Male, age 51, unknown 19.8
1815 Male, age 53, unknown 19.2
1944 Female, age 72, unknown 18.7
2316 Male, age 76, right hemisphere 18.5
2667 Female, age 75, unknown 18.4
2407 Male, age 75, both hemispheres 18.2
1817 Female, age 42, unknown 16.3
Red nucleus
nTPM: 18.6
2725 Female, age 75, unknown 23.1
2584 Male, age 75, left hemisphere 23.0
2588 Male, age 74, left hemisphere 20.5
2503 Female, age 72, unknown 18.7
2227 Male, age 72, unknown 18.2
2769 Male, age 72, unknown 18.2
1821 Female, age 72, unknown 18.1
2823 Male, age 76, right hemisphere 17.4
1954 Female, age 42, unknown 17.1
1865 Male, age 51, unknown 16.8
1904 Male, age 53, unknown 16.3
2785 Male, age 18, unknown 16.1
Substantia nigra
nTPM: 26.1
2699 Male, age 18, unknown 32.3
2590 Female, age 75, unknown 31.8
2583 Male, age 75, right hemisphere 29.8
2665 Male, age 74, both hemispheres 28.9
2241 Male, age 72, unknown 24.4
1916 Female, age 42, unknown 24.1
1889 Female, age 72, unknown 23.8
1851 Male, age 51, unknown 23.5
2409 Female, age 72, unknown 23.3
1941 Male, age 53, unknown 19.0
Superior colliculus
nTPM: 19.8
2261 Male, age 18, unknown 24.4
1796 Male, age 53, unknown 23.4
2664 Male, age 75, both hemispheres 23.4
1895 Male, age 76, right hemisphere 22.2
1839 Male, age 51, unknown 21.2
2587 Male, age 74, left hemisphere 18.4
2087 Female, age 72, unknown 17.5
2668 Female, age 75, unknown 16.6
1913 Female, age 42, unknown 15.9
1995 Male, age 72, unknown 15.2
Ventral tegmental area
nTPM: 30.0
2021 Male, age 53, unknown 39.7
1942 Male, age 51, unknown 31.9
1915 Female, age 42, unknown 31.4
2218 Male, age 76, both hemispheres 31.4
2410 Female, age 72, unknown 25.2
2223 Female, age 72, unknown 20.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 54.2
Samples: 139

Max nTPM: 194.0
Min nTPM: 5.7
Std nTPM: 31.9
Median nTPM: 49.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 194.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 183.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 144.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 142.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 124.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 120.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 118.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 115.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 100.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 98.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 94.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 93.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 91.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 90.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 87.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 85.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 84.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 84.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 83.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 81.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 81.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 81.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 81.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 80.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 80.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 77.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 77.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 75.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 74.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 73.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 73.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 72.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 71.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 71.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 69.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 67.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 66.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 66.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 64.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 63.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 62.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 61.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 61.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 60.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 60.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 60.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 60.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 60.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 59.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 59.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 58.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 58.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 58.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 57.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 55.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 54.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 54.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 54.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 52.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 52.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 52.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 52.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 52.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 51.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 50.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 50.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 49.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 49.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 48.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 48.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 48.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 48.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 48.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 47.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 47.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 46.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 45.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 44.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 44.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 44.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 43.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 43.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 42.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 42.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 39.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 39.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 39.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 39.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 39.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 39.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 39.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 39.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 38.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 38.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 35.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 34.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 34.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 34.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 34.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 32.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 31.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 31.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 31.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 31.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 31.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 30.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 30.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 30.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 29.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 28.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 27.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 27.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 27.3
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 27.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 25.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 25.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 24.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 24.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 24.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 23.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 23.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 21.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 20.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 19.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 17.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 17.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 17.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 17.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 16.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 10.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 10.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 9.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 9.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 8.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 7.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 7.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 5.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 10.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 10.3
FF:10158-103A5 76 years, female 10.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 7.8
Pig sample Sample description nTPM
Midbrain
nTPM: 7.2
Samples: 4

Max nTPM: 16.5
Min nTPM: 0.9
Sample A Female 0.9
Sample B Female 5.1
Sample C Male 16.5
Sample D Male 6.1
Periaqueductal gray
nTPM: 5.6
Samples: 3

Max nTPM: 8.5
Min nTPM: 4.0
Sample B Female 4.0
Sample C Male 8.5
Sample D Male 4.3
Substantia nigra
nTPM: 3.4
Samples: 4

Max nTPM: 5.1
Min nTPM: 0.9
Sample A Female 5.1
Sample B Female 4.6
Sample C Male 3.1
Sample D Male 0.9
Superior colliculi
nTPM: 7.8
Samples: 4

Max nTPM: 12.6
Min nTPM: 1.8
Sample A Female 5.7
Sample B Female 1.8
Sample C Male 11.0
Sample D Male 12.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 59.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 59.7
Samples: 4

Max nTPM: 65.3
Min nTPM: 53.2
Sample A Male 56.9
Sample B Male 53.2
Sample C Female 63.4
Sample D Female 65.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.0
70430708 Antisense, RP_050614_01_H06, Mouse strain C57BL/6J (56 days, male) 4.0
72008305 Antisense, RP_050614_01_H06, Mouse strain C57BL/6J (56 days, male) 1.7

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