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GPM6A
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  • GPM6A
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:265.4 nTPM
HPA:265.4 nTPM
GTEx:147.4 nTPM
FANTOM5:172.8 Scaled Tags Per Million
Pig:264.5 nTPM
Mouse:522.0 nTPM
Allen mouse:16.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 265.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 219.6
1827 Male, age 72, unknown 258.1
2219 Male, age 76, both hemispheres 253.2
2828 Female, age 72, unknown 251.7
1870 Female, age 42, unknown 220.9
2586 Male, age 75, left hemisphere 220.3
1833 Male, age 53, unknown 211.6
2411 Female, age 72, unknown 203.4
1830 Male, age 51, unknown 202.4
2666 Male, age 74, left hemisphere 189.5
2019 Male, age 18, unknown 185.3
Dorsal raphe nucleus
nTPM: 232.0
2298 Female, age 72, unknown 267.3
2047 Male, age 72, unknown 231.4
2016 Female, age 72, unknown 230.3
1828 Male, age 53, unknown 224.2
2750 Male, age 76, both hemispheres 206.7
Inferior colliculus
nTPM: 259.9
2097 Female, age 72, unknown 282.6
1848 Female, age 42, unknown 274.7
1890 Male, age 53, unknown 242.4
2849 Male, age 72, unknown 239.8
Median raphe nucleus
nTPM: 204.1
2220 Male, age 76, midline 204.1
Pedunculopontine tegmental nucleus
nTPM: 213.2
1921 Female, age 85, both hemispheres 260.8
2334 Male, age 80, both hemispheres 203.2
2338 Male, age 61, both hemispheres 175.4
Periaquaductal grey, anterior
nTPM: 265.4
1947 Male, age 18, unknown 292.0
1795 Male, age 51, unknown 255.9
2502 Female, age 75, unknown 248.2
Periaquaductal grey, dorsal
nTPM: 253.7
1840 Male, age 53, unknown 303.7
2464 Female, age 72, unknown 248.7
2850 Male, age 76, both hemispheres 242.5
1831 Male, age 72, unknown 220.0
Periaquaductal grey, lateral
nTPM: 242.9
2053 Male, age 18, unknown 273.6
2140 Male, age 76, both hemispheres 247.5
2272 Male, age 74, both hemispheres 207.7
Pretectal area
nTPM: 259.5
2273 Male, age 74, both hemispheres 300.6
2667 Female, age 75, unknown 284.7
1816 Male, age 51, unknown 281.4
2224 Female, age 72, unknown 275.0
2825 Male, age 18, unknown 264.2
1944 Female, age 72, unknown 258.7
1817 Female, age 42, unknown 247.5
2316 Male, age 76, right hemisphere 244.9
1815 Male, age 53, unknown 238.5
2407 Male, age 75, both hemispheres 235.7
2007 Male, age 72, unknown 223.6
Red nucleus
nTPM: 210.6
2503 Female, age 72, unknown 229.4
2725 Female, age 75, unknown 229.1
1821 Female, age 72, unknown 228.3
1954 Female, age 42, unknown 221.6
2769 Male, age 72, unknown 218.3
2227 Male, age 72, unknown 217.5
1904 Male, age 53, unknown 214.6
2823 Male, age 76, right hemisphere 213.3
1865 Male, age 51, unknown 204.9
2588 Male, age 74, left hemisphere 196.8
2785 Male, age 18, unknown 178.1
2584 Male, age 75, left hemisphere 175.5
Substantia nigra
nTPM: 222.6
2241 Male, age 72, unknown 243.0
1916 Female, age 42, unknown 242.0
1889 Female, age 72, unknown 241.4
2699 Male, age 18, unknown 233.9
1851 Male, age 51, unknown 229.1
2409 Female, age 72, unknown 225.4
2590 Female, age 75, unknown 209.6
2583 Male, age 75, right hemisphere 205.5
2665 Male, age 74, both hemispheres 204.0
1941 Male, age 53, unknown 192.6
Superior colliculus
nTPM: 244.7
1796 Male, age 53, unknown 279.2
2261 Male, age 18, unknown 270.5
2087 Female, age 72, unknown 264.0
2664 Male, age 75, both hemispheres 250.4
1839 Male, age 51, unknown 245.8
1895 Male, age 76, right hemisphere 241.8
1995 Male, age 72, unknown 236.4
2668 Female, age 75, unknown 226.2
2587 Male, age 74, left hemisphere 217.3
1913 Female, age 42, unknown 215.5
Ventral tegmental area
nTPM: 229.3
2223 Female, age 72, unknown 235.8
2021 Male, age 53, unknown 234.3
1915 Female, age 42, unknown 230.7
1942 Male, age 51, unknown 229.5
2410 Female, age 72, unknown 227.8
2218 Male, age 76, both hemispheres 217.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 147.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 147.4
Samples: 139

Max nTPM: 377.1
Min nTPM: 22.5
Std nTPM: 58.1
Median nTPM: 145.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 377.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 299.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 291.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 288.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 286.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 274.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 252.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 244.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 235.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 233.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 230.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 224.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 224.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 221.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 215.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 212.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 211.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 211.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 210.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 207.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 205.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 203.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 197.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 196.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 193.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 186.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 185.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 185.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 185.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 184.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 183.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 182.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 180.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 179.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 179.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 177.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 176.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 174.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 172.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 171.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 171.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 170.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 169.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 168.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 167.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 167.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 166.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 166.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 165.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 165.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 165.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 160.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 159.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 158.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 158.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 157.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 156.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 156.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 155.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 155.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 153.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 151.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 150.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 149.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 149.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 147.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 146.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 145.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 145.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 145.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 143.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 143.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 142.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 141.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 140.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 139.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 139.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 138.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 138.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 137.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 134.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 130.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 128.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 127.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 126.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 126.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 123.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 122.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 122.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 122.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 122.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 122.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 121.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 121.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 121.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 120.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 120.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 119.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 118.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 117.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 114.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 112.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 111.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 109.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 108.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 106.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 106.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 103.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 103.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 103.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 99.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 97.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 96.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 94.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 93.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 93.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 92.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 85.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 85.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 84.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 84.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 82.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 82.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 81.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 80.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 77.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 77.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 77.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 76.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 69.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 62.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 60.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 57.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 51.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 49.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 46.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 31.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 22.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 172.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 172.8
FF:10158-103A5 76 years, female 172.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 264.5
Pig sample Sample description nTPM
Midbrain
nTPM: 264.6
Samples: 4

Max nTPM: 342.1
Min nTPM: 220.4
Sample A Female 342.1
Sample B Female 233.2
Sample C Male 262.5
Sample D Male 220.4
Periaqueductal gray
nTPM: 236.1
Samples: 3

Max nTPM: 243.4
Min nTPM: 221.8
Sample B Female 243.4
Sample C Male 243.2
Sample D Male 221.8
Substantia nigra
nTPM: 197.4
Samples: 4

Max nTPM: 253.9
Min nTPM: 160.9
Sample A Female 253.9
Sample B Female 175.3
Sample C Male 199.3
Sample D Male 160.9
Superior colliculi
nTPM: 186.0
Samples: 4

Max nTPM: 211.4
Min nTPM: 125.1
Sample A Female 211.4
Sample B Female 125.1
Sample C Male 196.8
Sample D Male 210.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 522.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 522.0
Samples: 4

Max nTPM: 545.4
Min nTPM: 500.6
Sample A Male 500.6
Sample B Male 526.1
Sample C Female 545.4
Sample D Female 516.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 16.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.5
68080704 Antisense, RP_040929_01_G03, Mouse strain C57BL/6J (56 days, male) 16.5

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