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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:135.9 nTPM
HPA:135.9 nTPM
GTEx:136.7 nTPM
FANTOM5:84.6 Scaled Tags Per Million
Pig:142.9 nTPM
Mouse:53.1 nTPM
Allen mouse:3.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 135.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 110.0
2586 Male, age 75, left hemisphere 155.9
1827 Male, age 72, unknown 128.1
2828 Female, age 72, unknown 126.5
1870 Female, age 42, unknown 113.0
2411 Female, age 72, unknown 102.8
2666 Male, age 74, left hemisphere 101.9
2219 Male, age 76, both hemispheres 99.4
1833 Male, age 53, unknown 98.2
2019 Male, age 18, unknown 89.7
1830 Male, age 51, unknown 84.4
Dorsal raphe nucleus
nTPM: 124.2
1828 Male, age 53, unknown 147.7
2016 Female, age 72, unknown 142.6
2298 Female, age 72, unknown 124.2
2047 Male, age 72, unknown 121.8
2750 Male, age 76, both hemispheres 84.7
Inferior colliculus
nTPM: 135.9
1848 Female, age 42, unknown 140.6
2849 Male, age 72, unknown 138.2
2097 Female, age 72, unknown 137.6
1890 Male, age 53, unknown 127.3
Median raphe nucleus
nTPM: 83.7
2220 Male, age 76, midline 83.7
Pedunculopontine tegmental nucleus
nTPM: 89.6
1921 Female, age 85, both hemispheres 101.4
2334 Male, age 80, both hemispheres 89.8
2338 Male, age 61, both hemispheres 77.6
Periaquaductal grey, anterior
nTPM: 121.2
1795 Male, age 51, unknown 133.0
2502 Female, age 75, unknown 128.1
1947 Male, age 18, unknown 102.5
Periaquaductal grey, dorsal
nTPM: 121.1
1840 Male, age 53, unknown 157.3
2464 Female, age 72, unknown 128.9
1831 Male, age 72, unknown 105.7
2850 Male, age 76, both hemispheres 92.6
Periaquaductal grey, lateral
nTPM: 112.1
2053 Male, age 18, unknown 140.2
2140 Male, age 76, both hemispheres 103.8
2272 Male, age 74, both hemispheres 92.4
Pretectal area
nTPM: 127.4
1944 Female, age 72, unknown 174.3
1816 Male, age 51, unknown 168.5
2667 Female, age 75, unknown 165.3
2224 Female, age 72, unknown 133.2
1817 Female, age 42, unknown 123.1
2007 Male, age 72, unknown 114.3
2825 Male, age 18, unknown 111.0
2316 Male, age 76, right hemisphere 109.9
2273 Male, age 74, both hemispheres 107.7
1815 Male, age 53, unknown 105.7
2407 Male, age 75, both hemispheres 88.7
Red nucleus
nTPM: 102.0
2503 Female, age 72, unknown 122.7
2227 Male, age 72, unknown 115.0
2769 Male, age 72, unknown 112.4
1954 Female, age 42, unknown 108.1
2725 Female, age 75, unknown 106.4
1821 Female, age 72, unknown 106.1
2588 Male, age 74, left hemisphere 104.2
2584 Male, age 75, left hemisphere 94.5
1904 Male, age 53, unknown 93.0
2785 Male, age 18, unknown 91.0
2823 Male, age 76, right hemisphere 88.2
1865 Male, age 51, unknown 82.8
Substantia nigra
nTPM: 133.9
1916 Female, age 42, unknown 155.3
2699 Male, age 18, unknown 152.8
2665 Male, age 74, both hemispheres 147.2
1851 Male, age 51, unknown 136.8
2241 Male, age 72, unknown 134.5
1889 Female, age 72, unknown 132.3
2583 Male, age 75, right hemisphere 128.9
2409 Female, age 72, unknown 128.5
1941 Male, age 53, unknown 111.4
2590 Female, age 75, unknown 111.2
Superior colliculus
nTPM: 118.8
2087 Female, age 72, unknown 145.7
2261 Male, age 18, unknown 143.9
1796 Male, age 53, unknown 142.4
2664 Male, age 75, both hemispheres 134.1
1839 Male, age 51, unknown 124.9
2587 Male, age 74, left hemisphere 114.3
1895 Male, age 76, right hemisphere 104.8
2668 Female, age 75, unknown 94.6
1913 Female, age 42, unknown 92.6
1995 Male, age 72, unknown 90.9
Ventral tegmental area
nTPM: 117.0
2410 Female, age 72, unknown 138.0
1915 Female, age 42, unknown 134.8
1942 Male, age 51, unknown 115.1
2021 Male, age 53, unknown 106.9
2218 Male, age 76, both hemispheres 103.8
2223 Female, age 72, unknown 103.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 136.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 136.7
Samples: 139

Max nTPM: 389.3
Min nTPM: 43.4
Std nTPM: 64.9
Median nTPM: 123.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 389.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 361.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 283.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 282.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 281.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 277.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 277.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 269.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 247.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 245.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 240.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 237.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 236.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 231.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 227.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 218.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 217.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 209.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 204.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 202.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 202.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 201.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 197.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 192.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 191.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 189.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 187.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 187.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 186.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 185.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 183.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 183.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 181.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 181.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 180.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 176.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 170.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 165.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 164.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 162.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 156.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 154.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 153.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 153.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 153.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 151.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 150.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 150.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 150.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 149.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 147.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 143.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 143.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 138.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 135.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 135.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 135.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 134.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 133.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 131.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 130.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 129.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 125.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 125.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 125.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 124.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 124.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 123.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 123.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 123.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 122.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 122.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 121.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 119.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 117.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 115.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 115.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 115.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 115.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 114.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 114.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 113.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 112.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 107.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 107.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 104.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 104.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 103.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 103.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 103.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 102.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 102.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 101.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 101.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 100.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 100.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 99.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 98.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 97.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 96.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 95.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 93.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 93.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 92.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 92.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 90.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 89.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 87.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 87.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 87.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 86.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 83.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 81.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 81.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 79.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 76.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 75.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 75.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 74.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 71.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 70.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 68.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 64.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 63.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 62.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 61.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 61.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 61.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 59.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 57.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 57.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 55.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 54.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 53.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 52.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 49.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 45.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 43.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 43.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 84.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 84.6
FF:10158-103A5 76 years, female 84.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 142.9
Pig sample Sample description nTPM
Midbrain
nTPM: 142.9
Samples: 4

Max nTPM: 199.7
Min nTPM: 117.4
Sample A Female 199.7
Sample B Female 125.1
Sample C Male 129.4
Sample D Male 117.4
Periaqueductal gray
nTPM: 108.0
Samples: 3

Max nTPM: 115.3
Min nTPM: 99.5
Sample B Female 115.3
Sample C Male 109.3
Sample D Male 99.5
Substantia nigra
nTPM: 130.8
Samples: 4

Max nTPM: 153.3
Min nTPM: 90.4
Sample A Female 153.3
Sample B Female 90.4
Sample C Male 129.4
Sample D Male 150.1
Superior colliculi
nTPM: 125.2
Samples: 4

Max nTPM: 154.6
Min nTPM: 77.5
Sample A Female 154.6
Sample B Female 77.5
Sample C Male 125.3
Sample D Male 143.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 53.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 53.1
Samples: 4

Max nTPM: 54.6
Min nTPM: 52.1
Sample A Male 54.6
Sample B Male 53.3
Sample C Female 52.4
Sample D Female 52.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.2
69201588 Antisense, RP_050317_03_B12, Mouse strain C57BL/6J (56 days, male) 5.0
72119592 Antisense, RP_051017_04_A07, Mouse strain C57BL/6J (56 days, male) 2.5
71764156 Antisense, RP_050921_03_C11, Mouse strain C57BL/6J (56 days, male) 2.0

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