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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:175.1 nTPM
HPA:175.1 nTPM
GTEx:189.0 nTPM
FANTOM5:582.5 Scaled Tags Per Million
Pig:1.1 nTPM
Mouse:0.0 nTPM
Allen mouse:2.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 175.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 153.0
1870 Female, age 42, unknown 174.2
2411 Female, age 72, unknown 170.0
1833 Male, age 53, unknown 168.2
1830 Male, age 51, unknown 163.3
2019 Male, age 18, unknown 161.2
2828 Female, age 72, unknown 156.5
1827 Male, age 72, unknown 141.7
2219 Male, age 76, both hemispheres 141.5
2666 Male, age 74, left hemisphere 128.5
2586 Male, age 75, left hemisphere 125.2
Dorsal raphe nucleus
nTPM: 147.3
2750 Male, age 76, both hemispheres 171.5
2016 Female, age 72, unknown 150.3
2298 Female, age 72, unknown 143.2
1828 Male, age 53, unknown 140.6
2047 Male, age 72, unknown 131.1
Inferior colliculus
nTPM: 140.8
1848 Female, age 42, unknown 144.7
2097 Female, age 72, unknown 141.1
2849 Male, age 72, unknown 140.0
1890 Male, age 53, unknown 137.3
Median raphe nucleus
nTPM: 132.5
2220 Male, age 76, midline 132.5
Pedunculopontine tegmental nucleus
nTPM: 154.5
2334 Male, age 80, both hemispheres 157.5
2338 Male, age 61, both hemispheres 157.4
1921 Female, age 85, both hemispheres 148.6
Periaquaductal grey, anterior
nTPM: 132.3
1947 Male, age 18, unknown 135.6
2502 Female, age 75, unknown 131.8
1795 Male, age 51, unknown 129.7
Periaquaductal grey, dorsal
nTPM: 131.8
2464 Female, age 72, unknown 144.5
1831 Male, age 72, unknown 130.4
2850 Male, age 76, both hemispheres 127.4
1840 Male, age 53, unknown 125.1
Periaquaductal grey, lateral
nTPM: 137.3
2272 Male, age 74, both hemispheres 150.4
2053 Male, age 18, unknown 135.8
2140 Male, age 76, both hemispheres 125.6
Pretectal area
nTPM: 144.1
2667 Female, age 75, unknown 166.4
2273 Male, age 74, both hemispheres 154.9
2316 Male, age 76, right hemisphere 151.4
1815 Male, age 53, unknown 150.9
1817 Female, age 42, unknown 145.9
2407 Male, age 75, both hemispheres 143.3
2224 Female, age 72, unknown 143.2
2825 Male, age 18, unknown 139.4
2007 Male, age 72, unknown 136.5
1944 Female, age 72, unknown 129.6
1816 Male, age 51, unknown 123.7
Red nucleus
nTPM: 175.1
1904 Male, age 53, unknown 196.6
2823 Male, age 76, right hemisphere 195.0
1865 Male, age 51, unknown 186.1
1954 Female, age 42, unknown 185.9
2227 Male, age 72, unknown 184.9
2769 Male, age 72, unknown 184.8
1821 Female, age 72, unknown 184.4
2503 Female, age 72, unknown 181.2
2785 Male, age 18, unknown 175.9
2725 Female, age 75, unknown 152.9
2588 Male, age 74, left hemisphere 142.8
2584 Male, age 75, left hemisphere 130.7
Substantia nigra
nTPM: 143.0
1851 Male, age 51, unknown 156.4
2699 Male, age 18, unknown 152.2
2409 Female, age 72, unknown 150.5
1889 Female, age 72, unknown 149.2
2583 Male, age 75, right hemisphere 145.9
2590 Female, age 75, unknown 143.5
1916 Female, age 42, unknown 140.3
2241 Male, age 72, unknown 136.6
1941 Male, age 53, unknown 135.4
2665 Male, age 74, both hemispheres 119.7
Superior colliculus
nTPM: 148.3
1995 Male, age 72, unknown 176.0
1913 Female, age 42, unknown 175.5
1895 Male, age 76, right hemisphere 167.3
2587 Male, age 74, left hemisphere 153.3
1839 Male, age 51, unknown 145.5
1796 Male, age 53, unknown 142.3
2668 Female, age 75, unknown 139.1
2087 Female, age 72, unknown 135.6
2261 Male, age 18, unknown 127.5
2664 Male, age 75, both hemispheres 120.9
Ventral tegmental area
nTPM: 148.6
2410 Female, age 72, unknown 161.2
2223 Female, age 72, unknown 156.8
1915 Female, age 42, unknown 148.8
1942 Male, age 51, unknown 143.3
2218 Male, age 76, both hemispheres 141.2
2021 Male, age 53, unknown 140.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 189.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 189.0
Samples: 139

Max nTPM: 509.7
Min nTPM: 63.5
Std nTPM: 76.8
Median nTPM: 166.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 509.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 458.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 443.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 391.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 370.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 367.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 356.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 353.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 339.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 329.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 317.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 309.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 308.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 307.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 303.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 296.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 294.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 274.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 273.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 267.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 260.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 256.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 256.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 249.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 235.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 235.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 232.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 227.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 224.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 220.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 219.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 217.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 214.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 214.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 213.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 213.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 212.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 210.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 209.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 203.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 201.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 201.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 196.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 195.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 194.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 192.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 192.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 190.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 190.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 188.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 188.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 188.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 186.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 186.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 184.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 184.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 184.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 182.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 181.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 178.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 178.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 178.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 177.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 175.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 172.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 170.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 170.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 168.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 167.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 166.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 165.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 163.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 163.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 162.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 161.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 161.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 159.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 158.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 158.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 156.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 156.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 155.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 155.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 155.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 154.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 153.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 153.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 152.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 151.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 150.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 149.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 148.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 147.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 147.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 147.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 145.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 145.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 143.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 143.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 142.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 141.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 141.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 140.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 140.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 139.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 138.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 138.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 137.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 136.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 135.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 134.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 134.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 134.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 133.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 131.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 130.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 125.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 125.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 125.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 124.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 121.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 120.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 120.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 119.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 116.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 116.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 115.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 114.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 114.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 113.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 112.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 108.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 105.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 105.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 103.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 102.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 94.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 91.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 63.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 582.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 582.5
FF:10158-103A5 76 years, female 582.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1.1
Pig sample Sample description nTPM
Midbrain
nTPM: 36.3
Samples: 4

Max nTPM: 72.3
Min nTPM: 21.8
Sample A Female 72.3
Sample B Female 27.1
Sample C Male 21.8
Sample D Male 24.1
Periaqueductal gray
nTPM: 23.9
Samples: 3

Max nTPM: 25.3
Min nTPM: 21.4
Sample B Female 25.3
Sample C Male 21.4
Sample D Male 25.0
Substantia nigra
nTPM: 30.0
Samples: 4

Max nTPM: 39.5
Min nTPM: 19.4
Sample A Female 37.3
Sample B Female 19.4
Sample C Male 23.7
Sample D Male 39.5
Superior colliculi
nTPM: 33.9
Samples: 4

Max nTPM: 41.8
Min nTPM: 30.2
Sample A Female 41.8
Sample B Female 30.2
Sample C Male 33.0
Sample D Male 30.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 0.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 71.4
Samples: 4

Max nTPM: 78.3
Min nTPM: 62.9
Sample A Male 78.3
Sample B Male 71.0
Sample C Female 62.9
Sample D Female 73.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.9
68301431 Antisense, RP_041130_01_C04, Mouse strain C57BL/6J (56 days, male) 2.9
Midbrain
Expression energy: 2.9
68301431 Antisense, RP_041130_01_C04, Mouse strain C57BL/6J (56 days, male) 2.9

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