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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:203.9 nTPM
HPA:203.9 nTPM
GTEx:190.1 nTPM
FANTOM5:77.4 Scaled Tags Per Million
Pig:93.7 nTPM
Mouse:129.1 nTPM
Allen mouse:6.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 203.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 196.7
2411 Female, age 72, unknown 207.2
2019 Male, age 18, unknown 202.7
1827 Male, age 72, unknown 199.9
1870 Female, age 42, unknown 199.3
1833 Male, age 53, unknown 195.5
2828 Female, age 72, unknown 194.6
2219 Male, age 76, both hemispheres 193.9
1830 Male, age 51, unknown 193.8
2666 Male, age 74, left hemisphere 190.9
2586 Male, age 75, left hemisphere 189.0
Dorsal raphe nucleus
nTPM: 203.9
2298 Female, age 72, unknown 221.8
2047 Male, age 72, unknown 204.5
2750 Male, age 76, both hemispheres 202.5
1828 Male, age 53, unknown 198.1
2016 Female, age 72, unknown 192.9
Inferior colliculus
nTPM: 195.8
2097 Female, age 72, unknown 204.3
1890 Male, age 53, unknown 195.7
1848 Female, age 42, unknown 193.1
2849 Male, age 72, unknown 189.9
Median raphe nucleus
nTPM: 200.2
2220 Male, age 76, midline 200.2
Pedunculopontine tegmental nucleus
nTPM: 202.2
2334 Male, age 80, both hemispheres 205.4
1921 Female, age 85, both hemispheres 201.2
2338 Male, age 61, both hemispheres 200.0
Periaquaductal grey, anterior
nTPM: 201.5
2502 Female, age 75, unknown 202.5
1947 Male, age 18, unknown 202.3
1795 Male, age 51, unknown 199.6
Periaquaductal grey, dorsal
nTPM: 191.5
1840 Male, age 53, unknown 194.6
2464 Female, age 72, unknown 191.8
1831 Male, age 72, unknown 190.6
2850 Male, age 76, both hemispheres 189.0
Periaquaductal grey, lateral
nTPM: 195.0
2272 Male, age 74, both hemispheres 203.4
2053 Male, age 18, unknown 193.2
2140 Male, age 76, both hemispheres 188.3
Pretectal area
nTPM: 202.1
1944 Female, age 72, unknown 210.3
2007 Male, age 72, unknown 209.9
2273 Male, age 74, both hemispheres 209.2
1817 Female, age 42, unknown 208.8
1816 Male, age 51, unknown 207.9
2224 Female, age 72, unknown 204.2
1815 Male, age 53, unknown 200.7
2667 Female, age 75, unknown 200.3
2825 Male, age 18, unknown 191.9
2316 Male, age 76, right hemisphere 189.9
2407 Male, age 75, both hemispheres 189.8
Red nucleus
nTPM: 196.9
1821 Female, age 72, unknown 205.9
2503 Female, age 72, unknown 203.6
2785 Male, age 18, unknown 202.0
1954 Female, age 42, unknown 200.4
2725 Female, age 75, unknown 200.1
1865 Male, age 51, unknown 198.4
1904 Male, age 53, unknown 196.6
2227 Male, age 72, unknown 195.4
2769 Male, age 72, unknown 195.1
2823 Male, age 76, right hemisphere 190.7
2584 Male, age 75, left hemisphere 187.4
2588 Male, age 74, left hemisphere 186.8
Substantia nigra
nTPM: 203.6
1916 Female, age 42, unknown 214.9
1851 Male, age 51, unknown 210.9
1889 Female, age 72, unknown 209.8
1941 Male, age 53, unknown 206.6
2241 Male, age 72, unknown 204.3
2409 Female, age 72, unknown 202.2
2665 Male, age 74, both hemispheres 200.3
2699 Male, age 18, unknown 197.2
2590 Female, age 75, unknown 196.8
2583 Male, age 75, right hemisphere 193.2
Superior colliculus
nTPM: 196.4
2587 Male, age 74, left hemisphere 201.9
2087 Female, age 72, unknown 201.4
1796 Male, age 53, unknown 201.2
2261 Male, age 18, unknown 200.8
2668 Female, age 75, unknown 198.6
1895 Male, age 76, right hemisphere 195.6
1913 Female, age 42, unknown 194.6
1995 Male, age 72, unknown 193.2
1839 Male, age 51, unknown 190.8
2664 Male, age 75, both hemispheres 186.4
Ventral tegmental area
nTPM: 203.1
2410 Female, age 72, unknown 217.6
1915 Female, age 42, unknown 207.3
2218 Male, age 76, both hemispheres 202.9
1942 Male, age 51, unknown 198.8
2021 Male, age 53, unknown 196.6
2223 Female, age 72, unknown 195.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 190.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 190.1
Samples: 139

Max nTPM: 342.2
Min nTPM: 116.9
Std nTPM: 36.6
Median nTPM: 182.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 342.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 318.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 310.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 277.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 272.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 272.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 260.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 259.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 254.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 253.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 249.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 243.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 241.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 239.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 239.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 231.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 231.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 230.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 229.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 224.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 223.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 219.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 218.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 217.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 216.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 215.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 215.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 214.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 214.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 213.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 213.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 209.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 209.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 207.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 207.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 207.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 206.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 204.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 203.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 203.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 201.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 200.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 199.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 198.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 198.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 197.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 196.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 196.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 194.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 192.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 191.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 191.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 190.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 190.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 189.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 189.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 188.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 188.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 188.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 187.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 187.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 186.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 186.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 186.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 186.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 185.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 185.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 183.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 183.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 182.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 182.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 181.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 179.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 179.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 178.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 177.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 177.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 177.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 177.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 177.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 176.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 176.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 176.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 175.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 175.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 174.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 174.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 173.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 173.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 173.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 173.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 173.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 172.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 172.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 171.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 170.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 170.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 170.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 169.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 169.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 168.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 167.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 167.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 165.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 165.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 163.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 163.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 163.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 162.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 161.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 161.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 161.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 161.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 160.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 158.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 158.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 157.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 157.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 157.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 157.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 157.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 156.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 154.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 154.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 154.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 153.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 153.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 153.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 152.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 148.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 146.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 144.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 142.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 142.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 141.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 140.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 139.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 138.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 116.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 77.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 77.4
FF:10158-103A5 76 years, female 77.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 93.7
Pig sample Sample description nTPM
Midbrain
nTPM: 85.6
Samples: 4

Max nTPM: 114.1
Min nTPM: 68.9
Sample A Female 114.1
Sample B Female 78.7
Sample C Male 80.7
Sample D Male 68.9
Periaqueductal gray
nTPM: 64.1
Samples: 3

Max nTPM: 74.9
Min nTPM: 53.2
Sample B Female 64.2
Sample C Male 74.9
Sample D Male 53.2
Substantia nigra
nTPM: 80.2
Samples: 4

Max nTPM: 117.0
Min nTPM: 63.2
Sample A Female 117.0
Sample B Female 69.1
Sample C Male 71.6
Sample D Male 63.2
Superior colliculi
nTPM: 93.7
Samples: 4

Max nTPM: 115.3
Min nTPM: 78.2
Sample A Female 115.3
Sample B Female 91.3
Sample C Male 89.9
Sample D Male 78.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 129.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 129.2
Samples: 4

Max nTPM: 136.3
Min nTPM: 123.4
Sample A Male 131.5
Sample B Male 125.4
Sample C Female 123.4
Sample D Female 136.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.7
68196974 Antisense, RP_040928_01_A04, Mouse strain C57BL/6J (56 days, male) 6.7

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