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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:183.3 nTPM
HPA:183.3 nTPM
GTEx:172.1 nTPM
FANTOM5:294.5 Scaled Tags Per Million
Pig:166.9 nTPM
Mouse:321.8 nTPM
Allen mouse:25.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 183.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 164.2
2411 Female, age 72, unknown 183.4
1870 Female, age 42, unknown 178.2
2828 Female, age 72, unknown 171.0
1833 Male, age 53, unknown 165.0
2586 Male, age 75, left hemisphere 164.5
2019 Male, age 18, unknown 163.7
1830 Male, age 51, unknown 161.4
1827 Male, age 72, unknown 157.6
2666 Male, age 74, left hemisphere 149.5
2219 Male, age 76, both hemispheres 147.7
Dorsal raphe nucleus
nTPM: 172.0
2298 Female, age 72, unknown 184.6
2047 Male, age 72, unknown 178.5
2750 Male, age 76, both hemispheres 169.2
1828 Male, age 53, unknown 164.1
2016 Female, age 72, unknown 163.6
Inferior colliculus
nTPM: 164.3
2097 Female, age 72, unknown 181.1
1848 Female, age 42, unknown 165.0
1890 Male, age 53, unknown 163.9
2849 Male, age 72, unknown 147.0
Median raphe nucleus
nTPM: 166.4
2220 Male, age 76, midline 166.4
Pedunculopontine tegmental nucleus
nTPM: 169.5
2334 Male, age 80, both hemispheres 176.1
2338 Male, age 61, both hemispheres 167.7
1921 Female, age 85, both hemispheres 164.7
Periaquaductal grey, anterior
nTPM: 166.5
1795 Male, age 51, unknown 169.3
1947 Male, age 18, unknown 169.1
2502 Female, age 75, unknown 161.0
Periaquaductal grey, dorsal
nTPM: 154.3
2464 Female, age 72, unknown 158.5
1831 Male, age 72, unknown 153.8
1840 Male, age 53, unknown 153.7
2850 Male, age 76, both hemispheres 151.0
Periaquaductal grey, lateral
nTPM: 166.0
2140 Male, age 76, both hemispheres 171.2
2053 Male, age 18, unknown 166.4
2272 Male, age 74, both hemispheres 160.4
Pretectal area
nTPM: 165.0
2667 Female, age 75, unknown 194.3
2273 Male, age 74, both hemispheres 176.2
2224 Female, age 72, unknown 168.1
1817 Female, age 42, unknown 168.0
2007 Male, age 72, unknown 165.6
1815 Male, age 53, unknown 161.1
1944 Female, age 72, unknown 160.1
2825 Male, age 18, unknown 159.1
1816 Male, age 51, unknown 157.7
2316 Male, age 76, right hemisphere 154.8
2407 Male, age 75, both hemispheres 150.4
Red nucleus
nTPM: 181.3
1904 Male, age 53, unknown 202.7
1821 Female, age 72, unknown 200.8
1954 Female, age 42, unknown 198.2
2227 Male, age 72, unknown 196.6
2503 Female, age 72, unknown 194.8
2769 Male, age 72, unknown 187.0
1865 Male, age 51, unknown 177.9
2785 Male, age 18, unknown 173.8
2823 Male, age 76, right hemisphere 171.9
2725 Female, age 75, unknown 169.6
2588 Male, age 74, left hemisphere 155.4
2584 Male, age 75, left hemisphere 147.1
Substantia nigra
nTPM: 174.2
1916 Female, age 42, unknown 206.8
1851 Male, age 51, unknown 203.5
2699 Male, age 18, unknown 182.2
2583 Male, age 75, right hemisphere 177.8
1889 Female, age 72, unknown 175.8
2590 Female, age 75, unknown 162.1
2409 Female, age 72, unknown 161.9
2241 Male, age 72, unknown 160.2
1941 Male, age 53, unknown 156.9
2665 Male, age 74, both hemispheres 154.9
Superior colliculus
nTPM: 161.5
1913 Female, age 42, unknown 179.5
1796 Male, age 53, unknown 172.6
1995 Male, age 72, unknown 171.9
2587 Male, age 74, left hemisphere 163.5
2087 Female, age 72, unknown 162.1
2668 Female, age 75, unknown 159.9
2261 Male, age 18, unknown 159.8
2664 Male, age 75, both hemispheres 151.4
1839 Male, age 51, unknown 149.4
1895 Male, age 76, right hemisphere 145.2
Ventral tegmental area
nTPM: 183.3
1915 Female, age 42, unknown 207.5
2410 Female, age 72, unknown 189.0
1942 Male, age 51, unknown 178.3
2223 Female, age 72, unknown 178.1
2021 Male, age 53, unknown 177.5
2218 Male, age 76, both hemispheres 169.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 172.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 172.1
Samples: 139

Max nTPM: 490.3
Min nTPM: 92.5
Std nTPM: 52.5
Median nTPM: 162.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 490.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 442.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 290.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 275.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 266.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 266.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 264.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 261.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 252.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 240.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 240.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 234.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 233.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 231.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 220.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 217.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 217.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 214.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 214.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 214.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 212.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 208.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 208.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 206.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 206.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 203.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 203.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 198.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 196.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 194.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 194.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 193.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 193.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 193.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 191.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 189.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 188.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 185.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 185.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 184.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 182.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 182.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 181.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 181.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 179.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 179.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 178.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 176.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 175.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 174.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 173.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 173.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 172.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 172.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 171.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 170.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 169.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 169.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 168.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 168.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 168.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 166.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 166.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 165.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 165.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 164.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 164.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 163.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 163.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 162.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 162.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 161.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 161.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 160.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 158.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 158.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 157.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 157.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 156.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 156.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 154.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 153.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 153.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 153.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 153.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 153.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 153.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 152.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 151.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 150.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 149.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 149.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 148.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 148.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 148.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 147.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 145.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 145.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 145.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 145.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 144.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 142.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 142.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 142.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 141.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 141.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 141.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 141.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 141.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 140.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 139.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 136.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 134.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 133.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 132.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 131.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 130.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 129.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 127.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 127.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 127.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 126.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 126.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 125.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 125.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 124.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 122.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 122.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 121.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 120.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 118.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 118.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 114.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 113.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 112.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 105.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 102.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 100.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 92.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 294.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 294.5
FF:10158-103A5 76 years, female 294.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 166.9
Pig sample Sample description nTPM
Midbrain
nTPM: 164.6
Samples: 4

Max nTPM: 273.5
Min nTPM: 118.4
Sample A Female 273.5
Sample B Female 143.2
Sample C Male 123.3
Sample D Male 118.4
Periaqueductal gray
nTPM: 126.9
Samples: 3

Max nTPM: 133.5
Min nTPM: 115.5
Sample B Female 131.6
Sample C Male 133.5
Sample D Male 115.5
Substantia nigra
nTPM: 166.9
Samples: 4

Max nTPM: 191.7
Min nTPM: 151.8
Sample A Female 191.7
Sample B Female 151.8
Sample C Male 157.6
Sample D Male 166.5
Superior colliculi
nTPM: 164.1
Samples: 4

Max nTPM: 189.6
Min nTPM: 144.0
Sample A Female 189.6
Sample B Female 175.5
Sample C Male 147.3
Sample D Male 144.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 321.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 321.8
Samples: 4

Max nTPM: 330.9
Min nTPM: 306.6
Sample A Male 330.7
Sample B Male 318.9
Sample C Female 306.6
Sample D Female 330.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 25.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 25.2
293263 Antisense, RP_040617_01_A10, Mouse strain C57BL/6J (56 days, male) 25.2

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